Related papers: Actinium-225 Production with an Electron Accelerat…
Targeted Alpha Therapy potentially offers a more specific action in killing tumor cells and less damage to neighbouring normal cells compared to $\beta$-emitters. $^{225}$Ac along with three other $\alpha$-emitting daughter nuclei…
Cross sections for the formation of 225,227-Ac, 223,225-Ra, and 227-Th via the proton bombardment of natural thorium targets were measured at a nominal proton energy of 800 MeV. No earlier experimental cross section data for the production…
We recommended a new method from different perspective for the production of Ac-227, Ra-228, Th-228 and U-232 radioisotopes which have an important potential for use in radioisotope power systems (instead of Pu-238) and nuclear batteries,…
Targeted alpha-particle therapy (TAT) employs alpha-emitting radionuclides conjugated to tumor-targeting molecules to deliver localized radiation to cancer cells, showing great promise in treating metastatic cancers. Among these…
The production of 225Ac using either a proton or electron accelerator requires a target of 226Ra. Radium metal is difficult to work with and so a radium salt, such as radium carbonate, is preferred as a target material. Normally available…
Cross sections for 223,225Ra, 225Ac and 227Th production by the proton bombardment of natural thorium targets were measured at proton energies below 200 MeV. Our measurements are in good agreement with previously published data and offer a…
Targeted alpha-particle therapy (TAT) has great promise as a cancer treatment. Arguably the most promising TAT radionuclide that has been proposed is $^{225}$Ac. The development of $^{225}$Ac-based radiopharmaceuticals has been hampered due…
Tritium is a well-known byproduct of particle accelerator operations. To keep levels of tritium below regulatory limits, tritium production is actively monitored and managed at Fermilab. We plan to study tritium production in the targets,…
The experimental cross sections of Pa-230 formation in the reaction 232Th(p,3n)230Pa for the protons energy range of 140-35 MeV are determined and compared with literature data. The yield of U-230 and impurities of U-232 and U-233 depending…
Diffusing alpha-emitters Radiation Therapy (Alpha DaRT) enables the use of alpha particles for the treatment of solid tumors. It employs interstitial sources carrying a few uCi of Ra-224, designed to release its short-lived progeny, which…
In order to fulfil the recent thrust of Astatine radionuclides in the field of nuclear medicine various production routes have been explored in the present work. The possible production routes of $^{209-211}$At comprise both light and heavy…
225Ac is a valuable medical radionuclide for targeted alpha therapy, but 227Ac is an undesirable byproduct of an accelerator-based synthesis method under investigation. Sufficient detector sensitivity is critical for quantifying the trace…
Short lived $^{212,213,214}$Ra isotopes have been produced at the TRI$\mu$P facility in inverse kinematics via the fusion-evaporation reaction $^{206}$Pb+$^{12}$C at 8 MeV/u. Isotopes are separated from other reaction products online using…
We study the production of radioisotopes for nuclear medicine in (gamma,gamma') photoexcitation reactions or (gamma,xn + yp) photonuclear reactions for the examples of ^195mPt, ^117mSn and ^44Ti with high flux [(10^13 - 10^15) gamma/s],…
The 75-keV injector and 6.7-MeV RFQ that comprise the first portion of the cw, 100-mA proton linac for the accelerator production of tritium (APT) project have been built and operated. The LEDA RFQ has been extensively tested for pulsed and…
The energy spectrum of alpha particles from the nuclear reaction p + $^{11}$B $\rightarrow 3\alpha$ was studied using the beam of the injector of the proton synchrotron of the Prometheus proton therapy complex. The reaction products (alpha…
Targeted Radionuclide Therapy (TRT) is a well-established technique for cancer treatment. In this approach, radionuclides are bound to specific drugs that selectively transport them to the tumor site. Within the ISOLPHARM project, a…
Four different techniques were applied for the production of $^{233}$U alpha recoil ion sources, providing $^{229}$Th ions. They were compared with respect to a minimum energy spread of the $^{229}$Th recoil ions, using the emitted alpha…
Fast neutron beams are of relevance for many scientific and industrial applications. This paper explores fast neutron production using a TANDEM accelerator at the Legnaro National Laboratories, via an energetic ion beam (90 MeV $^{14}N$)…
BACKGROUND: 155Tb represents a potentially useful radionuclide for diagnostic medical applications, but its production remains a challenging problem. A recent experimental campaign, conducted with low-energy proton beams impinging on a…