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Deep neural networks (DNNs) are widely studied in various applications. A DNN consists of layers of neurons that compute affine combinations, apply nonlinear operations, and produce corresponding activations. The rectified linear unit…

Machine Learning · Computer Science 2024-02-13 Navid Aftabi , Nima Moradi , Fatemeh Mahroo

We present a technique for neural network verification using mixed-integer programming (MIP) formulations. We derive a \emph{strong formulation} for each neuron in a network using piecewise linear activation functions. Additionally, as in…

Machine Learning · Computer Science 2022-11-29 Tu Anh-Nguyen , Joey Huchette

In fields such as autonomous and safety-critical systems, online optimization plays a crucial role in control and decision-making processes, often requiring the integration of continuous and discrete variables. These tasks are frequently…

Optimization and Control · Mathematics 2025-03-17 Marco Zamponi , Emilio Incerto , Daniele Masti , Mirco Tribastone

Mixed-integer linear programs (MILPs) are extensively used to model practical problems such as planning and scheduling. A prominent method for solving MILPs is large neighborhood search (LNS), which iteratively seeks improved solutions…

Optimization and Control · Mathematics 2024-12-12 Wenbo Liu , Akang Wang , Wenguo Yang , Qingjiang Shi

Sequential quadratic programming and sequential convex programming efficiently solve nonlinear programs (NLPs) by linearizing inner nonlinearities while preserving the outer convex structure. This paper introduces a sequential mixed-integer…

Optimization and Control · Mathematics 2026-03-27 Andrea Ghezzi , Wim Van Roy , Sebastian Sager , Moritz Diehl

Mixed-Integer Linear Programming (MILP) is a powerful framework used to address a wide range of NP-hard combinatorial optimization problems, often solved by Branch and Bound (B&B). A key factor influencing the performance of B&B solvers is…

Machine Learning · Computer Science 2025-10-23 Paul Strang , Zacharie Alès , Côme Bissuel , Olivier Juan , Safia Kedad-Sidhoum , Emmanuel Rachelson

This paper introduces scalable, sampling-based algorithms that optimize trained neural networks with ReLU activations. We first propose an iterative algorithm that takes advantage of the piecewise linear structure of ReLU neural networks…

Optimization and Control · Mathematics 2022-06-07 Georgia Perakis , Asterios Tsiourvas

Integer programming (IP) is a general optimization framework widely applicable to a variety of unstructured and structured problems arising in, e.g., scheduling, production planning, and graph optimization. As IP models many provably hard…

Machine Learning · Computer Science 2020-07-22 Yunhao Tang , Shipra Agrawal , Yuri Faenza

Mixed-integer programming (MIP) is a well-established framework for computer-aided molecular design (CAMD). By precisely encoding the molecular space and score functions, e.g., a graph neural network, the molecular design problem is…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Shiqiang Zhang , Christian W. Feldmann , Frederik Sandfort , Miriam Mathea , Juan S. Campos , Ruth Misener

Cutting planes and branching are two of the most important algorithms for solving mixed-integer linear programs. For both algorithms, disjunctions play an important role, being used both as branching candidates and as the foundation for…

Optimization and Control · Mathematics 2023-07-10 Mark Turner , Timo Berthold , Mathieu Besançon , Thorsten Koch

Mixed integer nonlinear programs (MINLPs) are arguably among the hardest optimization problems, with a wide range of applications. MINLP solvers that are based on linear relaxations and spatial branching work similar as mixed integer…

Optimization and Control · Mathematics 2019-02-08 Jakob Witzig , Timo Berthold , Stefan Heinz

Cutting planes (cuts) are crucial for solving Mixed Integer Linear Programming (MILP) problems. Advanced MILP solvers typically rely on manually designed heuristic algorithms for cut selection, which require much expert experience and…

Optimization and Control · Mathematics 2024-12-11 Xuefeng Zhang , Liangyu Chen , Zhengfeng Yang , Zhenbing Zeng

This paper considers how to fuse Machine Learning (ML) and optimization to solve large-scale Supply Chain Planning (SCP) optimization problems. These problems can be formulated as MIP models which feature both integer (non-binary) and…

Machine Learning · Computer Science 2025-04-11 Vahid Eghbal Akhlaghi , Reza Zandehshahvar , Pascal Van Hentenryck

Probing is an important presolving technique in mixed-integer programming solvers. It selects binary variables, tentatively fixes them to 0 and 1, and performs propagation to deduce additional variable fixings, bound tightenings,…

Optimization and Control · Mathematics 2026-01-05 Jacob von Holly-Ponientzietz , Alexander Hoen , Mark Turner , Ambros Gleixner

The current cut selection algorithm used in mixed-integer programming solvers has remained largely unchanged since its creation. In this paper, we propose a set of new cut scoring measures, cut filtering techniques, and stopping criteria,…

Optimization and Control · Mathematics 2023-07-18 Mark Turner , Timo Berthold , Mathieu Besançon

We present a batched first-order method for solving multiple linear programs in parallel on GPUs. Our approach extends the primal-dual hybrid gradient algorithm to efficiently solve batches of related linear programming problems that arise…

Optimization and Control · Mathematics 2026-01-30 Nicolas Blin , Stefano Gualandi , Christopher Maes , Andrea Lodi , Bartolomeo Stellato

We consider {\em Mixed Linear Regression (MLR)}, where training data have been generated from a mixture of distinct linear models (or clusters) and we seek to identify the corresponding coefficient vectors. We introduce a {\em Mixed Integer…

Machine Learning · Statistics 2019-09-10 Taiyao Wang , Ioannis Ch. Paschalidis

Determining what to eat to satisfy nutritional requirements is one of the oldest optimization problems in operations research, yet existing formulations have two persistent limitations: continuous variables produce impractical fractional…

Artificial Intelligence · Computer Science 2026-05-15 Francisco Aguilera Moreno

Covering problems are well-studied in the domain of Operations Research, and, more specifically, in Location Science. When the location space is a network, the most frequent assumption is to consider the candidate facility locations, the…

Optimization and Control · Mathematics 2023-01-18 Mercedes Pelegrín , Liding Xu

Mixed-Integer Linear Programs (MIPs) are powerful and flexible tools for modeling a wide range of real-world combinatorial optimization problems. Predict-and-Search methods operate by using a predictive model to estimate promising variable…

Artificial Intelligence · Computer Science 2026-04-21 Junyang Cai , El Mehdi Er Raqabi , Pascal Van Hentenryck , Bistra Dilkina
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