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Purpose: To organize a knee MRI segmentation challenge for characterizing the semantic and clinical efficacy of automatic segmentation methods relevant for monitoring osteoarthritis progression. Methods: A dataset partition consisting of 3D…

The purpose of this work is to develop a deep learning-based method for knee menisci segmentation in 3D ultrashort echo time (UTE) cones magnetic resonance (MR) imaging, and to automatically determine MR relaxation times, namely the T1,…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Michal Byra , Mei Wu , Xiaodong Zhang , Hyungseok Jang , Ya-Jun Ma , Eric Y Chang , Sameer Shah , Jiang Du

Knee Osteoarthritis (KOA) is the third most prevalent Musculoskeletal Disorder (MSD) after neck and back pain. To monitor such a severe MSD, a segmentation map of the femur, tibia and tibiofemoral cartilage is usually accessed using the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Akshay Daydar , Alik Pramanick , Arijit Sur , Subramani Kanagaraj

Knee osteoarthritis is a degenerative joint disease that induces chronic pain and disability. Bone morphological analysis is a promising tool to understand the mechanical aspect of this disorder. This study proposes a 2D bone morphological…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai

Objective: To establish an automated pipeline for post-processing of quantitative spin-lattice relaxation time constant in the rotating frame ($T_{1\rho}$) imaging of knee articular cartilage. Design: The proposed post-processing pipeline…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Junru Zhong , Yongcheng Yao , Fan Xiao , Tim-Yun Michael Ong , Ki-Wai Kevin Ho , Siyue Li , Chaoxing Huang , Queenie Chan , James F. Griffith , Weitian Chen

Purpose: To develop and evaluate cross-sequence transfer learning for automatic femoral cartilage segmentation, testing bidirectional transfer between dual-echo steady-state (DESS) and sagittal proton density-weighted 3D fast spin-echo…

Purpose: To propose and evaluate an accelerated $T_{1\rho}$ quantification method that combines $T_{1\rho}$-weighted fast spin echo (FSE) images and proton density (PD)-weighted anatomical FSE images, leveraging deep learning models for…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Junru Zhong , Chaoxing Huang , Ziqiang Yu , Fan Xiao , Siyue Li , Tim-Yun Michael Ong , Ki-Wai Kevin Ho , Queenie Chan , James F. Griffith , Weitian Chen

Purpose: To develop a deep learning method for the automatic segmentation of spinal nerve rootlets on various MRI scans. Material and Methods: This retrospective study included MRI scans from two open-access and one private dataset,…

Tissues and Organs · Quantitative Biology 2026-05-19 Katerina Krejci , Jiri Chmelik , Sandrine Bedard , Falk Eippert , Ulrike Horn , Virginie Callot , Julien Cohen-Adad , Jan Valosek

A fully automated knee MRI segmentation method to study osteoarthritis (OA) was developed using a novel hierarchical set of random forests (RF) classifiers to learn the appearance of cartilage regions and their boundaries. A neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Honghai Zhang , Karan Rao , Milan Sonka

Accurate morphometric assessment of cartilage-such as thickness/volume-via MRI is essential for monitoring knee osteoarthritis. Segmenting cartilage remains challenging and dependent on extensive expert-annotated datasets, which are heavily…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Danielle L. Ferreira , Bruno A. A. Nunes , Xuzhe Zhang , Laura Carretero Gomez , Maggie Fung , Ravi Soni

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

The automatic segmentation of human knee cartilage from 3D MR images is a useful yet challenging task due to the thin sheet structure of the cartilage with diffuse boundaries and inhomogeneous intensities. In this paper, we present an…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Quan Wang , Dijia Wu , Le Lu , Meizhu Liu , Kim L. Boyer , Shaohua Kevin Zhou

OBJECTIVES: Quantitative MRI techniques such as T2 and T1$\rho$ mapping are beneficial in evaluating cartilage and meniscus. We aimed to evaluate the MIXTURE (Multi-Interleaved X-prepared Turbo-Spin Echo with IntUitive RElaxometry)…

Precise identification of spinal nerve rootlets is relevant to delineate spinal levels for the study of functional activity in the spinal cord. The goal of this study was to develop an automatic method for the semantic segmentation of…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Jan Valosek , Theo Mathieu , Raphaelle Schlienger , Olivia S. Kowalczyk , Julien Cohen-Adad

Background: MRI is the modality of choice for cartilage imaging; however, its diagnostic performance is variable and significantly lower than the gold standard diagnostic knee arthroscopy. In recent years, deep learning has been used to…

Computer Vision and Pattern Recognition · Computer Science 2021-06-24 Gergo Merkely , Alireza Borjali , Molly Zgoda , Evan M. Farina , Simon Gortz , Orhun Muratoglu , Christian Lattermann , Kartik M. Varadarajan

Simulation studies like finite element (FE) modeling provide insight into knee joint mechanics without patient experimentation. Generic FE models represent biomechanical behavior of the tissue by overlooking variations in geometry, loading,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Reza Kakavand , Mehrdad Palizi , Peyman Tahghighi , Reza Ahmadi , Neha Gianchandani , Samer Adeeb , Roberto Souza , W. Brent Edwards , Amin Komeili

We present a fully automated learning-based approach for segmenting knee cartilage in the presence of osteoarthritis (OA). The algorithm employs a hierarchical set of two random forest classifiers. The first is a neighborhood approximation…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Ipek Oguz , Honghai Zhang , Milan Sonka

Quantifying muscle tissue properties is crucial for understanding pathophysiological changes occurring in skeletal muscle (SM). In particular, T2 relaxation and diffusion MRI (dMRI) are promising techniques. However, typical methods measure…

The aim of this study was to investigate the influence of MRI and patient data on the prediction of knee osteoarthritis (OA) incidence using different deep learning architectures. Knee OA incidence within 24 months was predicted using the…

Medical Physics · Physics 2022-09-05 Anastasis Alexopoulos , Jukka Hirvasniemi , Nazli Tümer

Simulation studies, such as finite element (FE) modeling, offer insights into knee joint biomechanics, which may not be achieved through experimental methods without direct involvement of patients. While generic FE models have been used to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Reza Kakavand , Peyman Tahghighi , Reza Ahmadi , W. Brent Edwards , Amin Komeili
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