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In the current study, our purpose is to evaluate the feasibility of applying deep learning (DL) enabled algorithms to quantify bilateral knee biomarkers in healthy controls scanned at 0.55T and compared with 3.0T. The current study assesses…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Rupsa Bhattacharjee , Zehra Akkaya , Johanna Luitjens , Pan Su , Yang Yang , Valentina Pedoia , Sharmila Majumdar

Purpose. To present SPINEPS, an open-source deep learning approach for semantic and instance segmentation of 14 spinal structures (ten vertebra substructures, intervertebral discs, spinal cord, spinal canal, and sacrum) in whole body T2w…

Imaging features of knee articular cartilage have been shown to be potential imaging biomarkers for knee osteoarthritis. Despite recent methodological advancements in image analysis techniques like image segmentation, registration, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Yongcheng Yao , Weitian Chen

Analyzing knee cartilage thickness and strain under load can help to further the understanding of the effects of diseases like Osteoarthritis. A precise segmentation of the cartilage is a necessary prerequisite for this analysis. This…

Intelligent medical image segmentation methods are rapidly evolving and being increasingly applied, yet they face the challenge of domain transfer, where algorithm performance degrades due to different data distributions between source and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Andrew Seohwan Yu , Mohsen Hariri , Xuecen Zhang , Mingrui Yang , Vipin Chaudhary , Xiaojuan Li

Background and Objective: Radiomics of knee MRI requires robust, anatomically meaningful regions of interest (ROIs) that jointly capture cartilage and subchondral bone. Most existing work relies on manual ROIs and rarely reports quality…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Tongxu Zhang , Zongpan Li , Aaron Kam Lun Leung , Siu Ngor Fu

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies

The 3D morphology and quantitative assessment of knee articular cartilages (i.e., femoral, tibial, and patellar cartilage) in magnetic resonance (MR) imaging is of great importance for knee radiographic osteoarthritis (OA) diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Chaowei Tan , Zhennan Yan , Shaoting Zhang , Kang Li , Dimitris N. Metaxas

Precision medicine in musculoskeletal imaging requires scalable measurement infrastructure. We developed a modular system that converts routine MRI into standardized quantitative biomarkers suitable for clinical decision support. Promptable…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Gabrielle Hoyer , Michelle W Tong , Rupsa Bhattacharjee , Valentina Pedoia , Sharmila Majumdar

A model-based reconstruction technique for accelerated T2 mapping with improved accuracy is proposed using undersampled Cartesian spin-echo MRI data. The technique employs an advanced signal model for T2 relaxation that accounts for…

Medical Physics · Physics 2015-03-03 Tilman J. Sumpf , Andreas Petrovic , Martin Uecker , Florian Knoll , Jens Frahm

Automatic CT segmentation of proximal femur is crucial for the diagnosis and risk stratification of orthopedic diseases; however, current methods for the femur CT segmentation mainly rely on manual interactive segmentation, which is…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Yu Deng , Ling Wang , Chen Zhao , Shaojie Tang , Xiaoguang Cheng , Hong-Wen Deng , Weihua Zhou

The high prevalence of spinal stenosis results in a large volume of MRI imaging, yet interpretation can be time-consuming with high inter-reader variability even among the most specialized radiologists. In this paper, we develop an…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Jen-Tang Lu , Stefano Pedemonte , Bernardo Bizzo , Sean Doyle , Katherine P. Andriole , Mark H. Michalski , R. Gilberto Gonzalez , Stuart R. Pomerantz

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

Medical Physics · Physics 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

Introduction: Quantitative MRI techniques such as T2 and T1\r{ho} mapping are beneficial in evaluating knee joint pathologies; however, long acquisition times limit their clinical adoption. MIXTURE (Multi-Interleaved X-prepared Turbo-Spin…

Convolutional neural networks like U-Net excel in medical image segmentation, while attention mechanisms and KAN enhance feature extraction. Meta's SAM 2 uses Vision Transformers for prompt-based segmentation without fine-tuning. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Mengyuan Liu , Yixiao Chen , Anning Tian , Xinmeng Wu , Mozhi Shen , Tianchou Gong , Jeongkyu Lee

We introduce CartiMorph, a framework for automated knee articular cartilage morphometrics. It takes an image as input and generates quantitative metrics for cartilage subregions, including the percentage of full-thickness cartilage loss…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Yongcheng Yao , Junru Zhong , Liping Zhang , Sheheryar Khan , Weitian Chen

Automatic segmentation of shoulder muscle MRI is challenging due to the high variation in muscle size, shape, texture, and spatial position of tears. Manual segmentation of tear and muscle portion is hard, time-consuming, and subjective to…

Image and Video Processing · Electrical Eng. & Systems 2021-08-27 Saddam Hussain Khan , Asifullah Khan , Yeon Soo Lee , Mehdi Hassan , Woong Kyo jeong

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Background: Accurate spinal structure measurement is crucial for assessing spine health and diagnosing conditions like spondylosis, disc herniation, and stenosis. Manual methods for measuring intervertebral disc height and spinal canal…