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We present a novel approach to represent ecological systems using reaction networks, and show how a particular framework called Chemical Organization Theory (COT) sheds new light on the longstanding complexity-stability debate. Namely, COT…

Populations and Evolution · Quantitative Biology 2019-11-20 Tomas Veloz

Non-classical negations may fail to be contradictory-forming operators in more than one way, and they often fail also to respect fundamental meta-logical properties such as the replacement property. Such drawbacks are witnessed by intricate…

Logic in Computer Science · Computer Science 2017-07-26 Ori Lahav , João Marcos , Yoni Zohar

The possible distinction between inanimate and living matter has been of interest to humanity since thousands of years. Clearly, such a rich question can not be answered in a single manner, and a plethora of approaches naturally do exist.…

Statistical Mechanics · Physics 2014-03-24 Constantino Tsallis

Life is commonly described as a self-organized, far-from-equilibrium process that maintains internal order by consuming free energy and exporting entropy. This thermodynamic view underlies diverse theoretical frameworks -- from autopoiesis…

Biological Physics · Physics 2025-12-23 Didier Sornette , Virgile Troude

In their recent comment, Cockell et al. argue that the habitability of an environment is fundamentally a binary property; that is to say, an environment can either support the metabolic processes of a given organism or not. The habitability…

Popular Physics · Physics 2020-04-15 René Heller

Empirical evidence suggesting that living systems might operate in the vicinity of critical points, at the borderline between order and disorder, has proliferated in recent years, with examples ranging from spontaneous brain activity to…

Statistical Mechanics · Physics 2014-07-25 Jorge Hidalgo , Jacopo Grilli , Samir Suweis , Miguel A. Munoz , Jayanth R. Banavar , Amos Maritan

Synthetic Biology is an interdisciplinary field that utilizes well-established engineering principles, ranging from electrical, control and computer systems, for analyzing the biological systems, such as biological circuits, enzymes,…

Logic in Computer Science · Computer Science 2019-12-25 Sa'ed Abed , Adnan Rashid , Osman Hasan

Biological evolution is a complex blend of ever changing structural stability, variability and emergence of new phenotypes, niches, ecosystems. We wish to argue that the evolution of life marks the end of a physics world view of law…

Other Quantitative Biology · Quantitative Biology 2012-01-11 Giuseppe Longo , Maël Montévil , Stuart Kauffman

Interactions with large language models have led to the suggestion that these models may soon be conscious. From the perspective of neuroscience, this position is difficult to defend. For one, the inputs to large language models lack the…

Neurons and Cognition · Quantitative Biology 2023-08-29 Jaan Aru , Matthew Larkum , James M. Shine

Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and…

General Physics · Physics 2008-05-30 Vasily Ogryzko

Living systems are typically characterized by irreversible processes. A condition equivalent to the reversibility is the detailed balance, whose absence is an obstacle for analytically solving ecological models. We revisit a promising model…

Statistical Mechanics · Physics 2012-11-20 Jacopo Grilli , Sandro Azaele , Jayanth R. Banavar , Amos Maritan

Notwithstanding its long history and compelling motivation, research seeking to explicate the emergence life (EoL) has throughout been a cacophony of unresolved speculation and dispute; absent still any clear convergence or other inarguable…

Populations and Evolution · Quantitative Biology 2023-12-05 Elbert Branscomb

Quantum mechanics provides a statistical description about nature, and thus would be incomplete if its statistical predictions could not be accounted for by some realistic models with hidden variables. There are, however, two powerful…

Quantum Physics · Physics 2012-10-04 Xi Kong , Mingjun Shi , Fazhan Shi , Pengfei Wang , Pu Huang , Qi Zhang , Chenyong Ju , Changkui Duan , Sixia Yu , Jiangfeng Du

In 1972, P.W.Anderson suggested that `More is Different', meaning that complex physical systems may exhibit behavior that cannot be understood only in terms of the laws governing their microscopic constituents. We strengthen this claim by…

Other Condensed Matter · Physics 2015-05-13 Mile Gu , Christian Weedbrook , Alvaro Perales , Michael A. Nielsen

Species coexistence is one of the central themes in modern ecology. Coexistence is a prerequisite of biological diversity. However, the question arises how biodiversity can be reconciled with the statement of competition theory, which…

Populations and Evolution · Quantitative Biology 2007-08-17 Dalius Balciunas

Unlike computation or the numerical analysis of differential equations, simulation does not have a well established conceptual and mathematical foundation. Simulation is an arguable unique union of modeling and computation. However,…

adap-org · Physics 2008-02-03 Steen Rasmussen , Christopher Barrett

The organism is a fundamental concept in biology. However there is no universally accepted, formal, and yet broadly applicable definition of what an organism is. Here we introduce a candidate definition. We adopt the view that the…

Other Quantitative Biology · Quantitative Biology 2016-12-02 Eric Libby , Joshua Grochow , Simon DeDeo , David Wolpert

There has been a long-standing and at times fractious debate whether complex and large systems can be stable. In ecology, the so-called `diversity-stability debate' arose because mathematical analyses of ecosystem stability were either…

Dynamical Systems · Mathematics 2015-09-02 Paul Kirk , Delphine M. Y. Rolando , Adam L. MacLean , Michael P. H. Stumpf

Mixed microbial communities, usually composed of various bacterial and fungal species, are fundamental in a plethora of environments, from soil to human gut and skin. Their evolution is a paradigmatic example of intertwined dynamics, where…

Populations and Evolution · Quantitative Biology 2022-07-01 Andrea Roli , Stuart A. Kauffman

This text introduces the twin deadlocks of strong artificial life. Conceptualization of life is a deadlock both because of the existence of a continuum between the inert and the living, and because we only know one instance of life.…

Artificial Intelligence · Computer Science 2007-05-23 J. -Ph Rennard