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Radical ontic structural realism (ROSR) asserts an ontological commitment to 'free-standing' physical structures understood solely in terms of fundamental relations, without any recourse to relata which stand in these relations. Bain (2011)…

History and Philosophy of Physics · Physics 2017-05-23 Vincent Lam , Christian Wuthrich

We extend the concept that life is an informational phenomenon, at every level of organisation, from molecules to the global ecological system. According to this thesis: (a) living is information processing, in which memory is maintained by…

Information Theory · Computer Science 2014-02-17 Keith D. Farnsworth , John Nelson , Carlos Gershenson

Many of life's most fascinating phenomena emerge from interactions among many elements--many amino acids determine the structure of a single protein, many genes determine the fate of a cell, many neurons are involved in shaping our thoughts…

Quantitative Methods · Quantitative Biology 2011-11-28 Thierry Mora , William Bialek

The two-dimensional cell-sorting problem is found to be mathematically equivalent to the one-dimensional random walk problem with pair creations and annihilations, i.e. the adhesion probabilities in the cell-sorting model relate…

Cell Behavior · Quantitative Biology 2011-07-01 Kazuhiko Minami

Individual choices often depend on the order in which the decisions are made. In this paper, we expose a general theory of measurable systems (an example of which is an individual's preferences) allowing for incompatible (non-commuting)…

Physics and Society · Physics 2007-06-20 V. I. Danilov , A. Lambert-Mogiliansky

The evolution of complexity has been a central theme for Biology [2] and Artificial Life research [1]. It is generally agreed that complexity has increased in our universe, giving way to life, multi-cellularity, societies, and systems of…

Populations and Evolution · Quantitative Biology 2011-09-06 Carlos Gershenson , Tom Lenaerts

This essay aims to propose construction theory, a new domain of theoretical research on machine construction, and use it to shed light on a fundamental relationship between living and computational systems. Specifically, we argue that…

Adaptation and Self-Organizing Systems · Physics 2009-09-29 Hiroki Sayama

The multifarious internal workings of organisms are difficult to reconcile with a single feature defining a state of being alive. Indeed, definitions of life rely on emergent properties (growth, capacity to evolve, agency) only symptomatic…

Other Quantitative Biology · Quantitative Biology 2023-08-16 Simon Pierce

Recent computational experiments have demonstrated the spontaneous emergence of self-replicating programs across universal automata, artificial chemistries, and self-modifying code systems. Remarkably, these results arise without explicit…

Logic in Computer Science · Computer Science 2026-01-27 Aritra Sarkar

Criticality has been proposed as a mechanism for the emergence of complexity, life, and computation, as it exhibits a balance between robustness and adaptability. In classic models of complex systems where structure and dynamics are…

Statistical Mechanics · Physics 2026-02-04 Fernanda Sánchez-Puig , Octavio Zapata , Omar K. Pineda , Gerardo Iñiguez , Carlos Gershenson

Abstracting an effective theory from a complicated process is central to the study of complexity. Even when the underlying mechanisms are understood, or at least measurable, the presence of dissipation and irreversibility in biological,…

Quantitative Methods · Quantitative Biology 2012-02-21 Simon DeDeo

The possibility of a fundamental consistency between the basic quantum principles and reduction (so-called wave function reduction) is reexamined. The mathematical description of an organized macroscopic device is constructed explicitly as…

Quantum Physics · Physics 2010-02-15 Roland Omnes

Quantum mechanics marks a radical departure from the classical understanding of Nature, fostering an inherent randomness which forbids a deterministic description; yet the most fundamental departure arises from something different. As shown…

Assembly Theory (AT) was developed to help distinguish living from non-living systems. The theory is simple as it posits that the amount of selection or Assembly is a function of the number of complex objects where their complexity can be…

Other Quantitative Biology · Quantitative Biology 2024-06-12 Sara I. Walker , Cole Mathis , Stuart Marshall , Leroy Cronin

Living systems are thermodynamically open but closed in their organization. In other words, even though their material components turn over constantly, a material-independent property persists, which we call organization. Moreover,…

Quantitative Methods · Quantitative Biology 2025-03-07 Pedro Márquez-Zacarías , Andrés Ortiz-Muñoz , Emma P. Bingham

Ashby's law of requisite variety states that a controller must have at least as much variety (complexity) as the controlled. Maturana and Varela proposed autopoiesis (self-production) to define living systems. Living systems also require to…

Adaptation and Self-Organizing Systems · Physics 2016-04-01 Carlos Gershenson

A notion of biologic system or just a system implies a functional wholeness of comprising system components. Positive and negative feedback are the examples of how the idea to unite anatomical elements in the whole functional structure was…

Other Quantitative Biology · Quantitative Biology 2014-06-03 Garri Davydyan

The problem of "what is 'system'?" is in the very foundations of modern quantum mechanics. Here, we point out the interest in this topic in the information-theoretic context. E.g., we point out the possibility to manipulate a pair of…

Quantum Physics · Physics 2012-02-21 M. Dugic , J. Jeknic-Dugic

Building on the Pusey-Barrett-Rudolph theorem, we derive a no-go theorem for a vast class of deterministic hidden-variables theories, including those consistent on their targeted domain. The strength of this result throws doubt on seemingly…

Quantum Physics · Physics 2014-02-25 Maximilian Schlosshauer , Arthur Fine

It is high time to openly and without finalism define the dangerous but needed term 'purposeful information', whose quantity is an Eigen information value. Using the term 'biological information' in its stead forces one into an…

Adaptation and Self-Organizing Systems · Physics 2011-12-01 Andrzej Gecow