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We consider the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-metapopulation model (including SIS, SIR, SEIR,. . .), when the loss function is given by the effective reproduction number Re, which is defined…

Optimization and Control · Mathematics 2021-10-26 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Most researches on adaptive networks mainly concentrate on the properties of steady state, but neglect transient dynamics. In this study, we pay attention to the emergence of community structures in transient process and the effects of…

Physics and Society · Physics 2015-06-05 Hui Yang , Ming Tang , Hai-Feng Zhang

We study global dynamics of an SIR model with vaccination, where we assume that individuals respond differently to dynamics of the epidemic. Their heterogeneous response is modeled by the Preisach hysteresis operator. We present a condition…

Dynamical Systems · Mathematics 2020-07-10 Jana Kopfová , Petra Nábělková , D. Rachinskii , S. Rouf

We revisit here a landmark five parameter SIR-type model of [DvdD93, Sec. 4], which is maybe the simplest example where a complete picture of all cases, including non-trivial bistability behavior, may be obtained using simple tools. We also…

Populations and Evolution · Quantitative Biology 2022-01-11 Florin Avram , Rim Adenane , Gianluca Bianchin , Andrei Halanay

When effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, home quarantine and far-reaching shutdown of public life are the only available strategies to prevent the spread…

Populations and Evolution · Quantitative Biology 2020-08-19 Markus Kantner , Thomas Koprucki

Whenever countries are threatened by a pandemic, as is the case with the COVID-19 virus, governments should take the right actions to safeguard public health as well as to mitigate the negative effects on the economy. In this regard, there…

Machine Learning · Computer Science 2020-05-18 Luis Miralles-Pechuán , Fernando Jiménez , Hiram Ponce , Lourdes Martínez-Villaseñor

In this study, we present an epidemic-controlled SIRD model with two types of control strategies: mask wear and screening. The aim of this study is to minimize the number of deceased keeping a minimal cost of mask advertising and screening.…

Populations and Evolution · Quantitative Biology 2021-09-06 Amira Bouhali , Walid Ben Aribi , Slimane Ben Miled , Amira Kebir

The Covid-19 outbreak of 2020 has required many governments to develop and adopt mathematical-statistical models of the pandemic for policy and planning purposes. To this end, this work provides a tutorial on building a compartmental model…

Applications · Statistics 2023-09-13 Elizabeth B Amona , Ryad A Ghanam , Edward L Boone , Indranil Sahoo , Laith J Abu-Raddad

We present a class of SEIR Markov chain models for infectious diseases observed over discrete time in a random human population living in a closed environment. The population changes over time through random births, deaths, and transitions…

Populations and Evolution · Quantitative Biology 2019-07-30 Divine Wanduku , Chinmoy Rahul

In this article, we introduce an infinite-dimensional deterministic SIS model which takes into account the heterogeneity of the infections and the social network among a large population. We study the long-time behavior of the dynamic. We…

Dynamical Systems · Mathematics 2020-06-16 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

An epidemic Susceptible-Vaccinated-Infected-Removed-Susceptible (SVIRS) model is presented on a weighted-undirected network with graph Laplacian diffusion. Disease-free equilibrium always exists while the existence and uniqueness of endemic…

Numerical Analysis · Mathematics 2025-03-25 Madhab Barman , Nachiketa Mishra

We study a susceptible-vaccinated--infected--recovered (SVIR) epidemic-spreading model with diversity of infection rate of the individuals. By means of analytical arguments as well as extensive computer simulations, we demonstrate that the…

Physics and Society · Physics 2013-12-05 Chao-Ran Cai , Zhi-Xi wu , Jian-Yue Guan

We analyze equilibrium behavior and optimal policy within a Susceptible-Infected-Recovered epidemic model augmented with potentially undiagnosed agents who infer their health status and a social planner with imperfect enforcement of social…

Theoretical Economics · Economics 2022-11-01 Thomas Phelan , Alexis Akira Toda

The Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model is one of the standard models of disease spreading. Here we analyse an extended SEIR model that accounts for asymptomatic carriers, believed to play an important role…

Populations and Evolution · Quantitative Biology 2021-01-26 Arghya Das , Abhishek Dhar , Srashti Goyal , Anupam Kundu , Saurav Pandey

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Probability · Mathematics 2021-02-26 Emanuel Javier Ferreyra , Matthieu Jonckheere , Juan Pablo Pinasco

Without vaccines and treatments, societies must rely on non-pharmaceutical intervention strategies to control the spread of emerging diseases such as COVID-19. Though complete lockdown is epidemiologically effective, because it eliminates…

Populations and Evolution · Quantitative Biology 2021-01-08 Jason Hindes , Simone Bianco , Ira B. Schwartz

In this paper we consider epidemic models of directly transmissible SIR (susceptible $\to$ infective $\to$ recovered) and SEIR (with an additional latent class) infections in fully-susceptible populations with a social structure, consisting…

Populations and Evolution · Quantitative Biology 2015-12-11 Frank Ball , Lorenzo Pellis , Pieter Trapman

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

Populations and Evolution · Quantitative Biology 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü

A pulse vaccination SIR model with periodic infection rate $\beta (t)$ have been proposed and studied. The basic reproductive number $R_0$ is defined. The dynamical behaviors of the model are analyzed with the help of persistence,…

Chaotic Dynamics · Physics 2009-05-29 Zhen Jin , Mainul Haque , Quanxing Liu

We investigate an infection-age structured competitive epidemiological model involving multiple strains. While classical results establish competitive exclusion when a unique maximal basic reproduction number exists, we provide here a…

Analysis of PDEs · Mathematics 2026-04-01 Simon Girel , Quentin Richard