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We study the dynamics of a SIR epidemic model with nonlinear incidence rate, vertical transmission vaccination for the newborns and the capacity of treatment, that takes into account the limitedness of the medical resources and the…

Dynamical Systems · Mathematics 2015-01-27 Erika Rivero-Esquivel , Eric Ávila-Vales , Gerardo E. García-Almeida

This paper studies algorithmic strategies to effectively reduce the number of infections in susceptible-infected-recovered (SIR) epidemic models. We consider a Markov chain SIR model and its two instantiations in the deterministic SIR…

Optimization and Control · Mathematics 2020-11-24 Yuhao Yi , Liren Shan , Philip E. Paré , Karl H. Johansson

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…

Populations and Evolution · Quantitative Biology 2022-03-18 Qi Luo , Ryan Weightman , Sean T. McQuade , Mateo Diaz , Emmanuel Trélat , William Barbour , Dan Work , Samitha Samaranayake , Benedetto Piccoli

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Optimization and Control · Mathematics 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

Based on the classical SIR model, we derive a simple modification for the dynamics of epidemics with a known incubation period of infection. The model is described by a system of integro-differential equations. Parameters of our model…

Populations and Evolution · Quantitative Biology 2021-09-01 David B. Saakian

The Susceptible-Exposed-Infectious-Recovered (SEIR) model is applied in several countries to ascertain the spread of the coronavirus disease 2019 (COVID-19). We consider discrete-time SEIR epidemic model in a closed system which does not…

Dynamical Systems · Mathematics 2021-05-04 U. A. Rozikov , S. K. Shoyimardonov

We consider a vaccination game that results with the introduction of premature and possibly scarce vaccines introduced in a desperate bid to combat the otherwise ravaging deadly pandemic. The response of unsure agents amid many…

Dynamical Systems · Mathematics 2021-09-14 Vartika Singh , Khushboo Agarwal , Shubham , Veeraruna Kavitha

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

In this paper we consider the stability of a class of deterministic and stochastic SEIRS epidemic models with delay. Indeed, we assume that the transmission rate could be stochastic and the presence of a latency period of $r$ consecutive…

Probability · Mathematics 2017-02-22 Xavier Bardina , Marco Ferrante , Carles Rovira

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

In this paper, we construct a model to describe the transmission of HIV in a homogeneous host population. By considering the specific mechanism of HIV, we derive a model structured in three successive stages: (i) primary infection, (ii)…

Analysis of PDEs · Mathematics 2019-11-18 Mboya Ba , Ramsès Djidjou-Demasse , Mountaga Lam , Jean-Jules Tewa

India is one of the worst affected countries by the Covid-19 pandemic at present. We studied publicly available data of the Covid-19 patients in India and analyzed possible impacts of quarantine and social distancing within the stochastic…

Populations and Evolution · Quantitative Biology 2020-06-12 Athokpam Langlen Chanu , R. K. Brojen Singh

We consider an age-structured epidemic model with two basic public health interventions: (i) identifying and isolating symptomatic cases, and (ii) tracing and quarantine of the contacts of identified infectives. The dynamics of the infected…

Populations and Evolution · Quantitative Biology 2014-03-13 Xi Huo

Vaccination has played an important role in preventing the spread of infectious diseases. However, the limited availability of vaccines and personnel at the roll-out of a new vaccine and the costs of vaccination campaigns often limit how…

Physics and Society · Physics 2026-01-27 Rowan Hoogervorst , Evelien van der Hurk , David Pisinger

In this paper, we investigate two major immunization strategies, random immunization and targeted immunization, of the susceptible-infected (SI) Model on the Barab\'{a}si-Albert (BA) networks. For the heterogenous structure, the random…

Biological Physics · Physics 2011-11-09 Wen-Jie Bai , Tao Zhou , Bing-Hong Wang

This paper is concerned with the spatio-temporal dynamics of an age-structured reaction-diffusion system of KPP-epidemic type (SIS), subject to Neumann boundary conditions and incorporating $L^1$ blow-up type death rate. We first establish…

Analysis of PDEs · Mathematics 2025-07-15 Cong-Bang Trang , Hoang-Hung Vo

This study focuses on investigating the manner in which a prompt quarantine measure suppresses epidemics in networks. A simple and ideal quarantine measure is considered in which an individual is detected with a probability immediately…

Physics and Society · Physics 2017-08-16 Takehisa Hasegawa , Koji Nemoto

We analyze a periodically-forced dynamical system inspired by the SIR model with impulsive vaccination. We fully characterize its dynamics according to the proportion $p$ of vaccinated individuals and the time $T$ between doses. If the…

Dynamical Systems · Mathematics 2024-08-02 João P. S. Maurício de Carvalho , Alexandre A. Rodrigues

The infection dynamics of a population under stationary isolation conditions is modeled. It is underlined that the stationary character of the isolation measures can be expected to imply that an effective SIR model with constant parameters…

Populations and Evolution · Quantitative Biology 2021-10-19 Alejandro Cabo Montes de Oca , Nana Geraldine Cabo Bizet

Diagnostic testing followed by isolation of identified cases with subsequent tracing and quarantine of close contacts - often referred to as test-trace-isolate-and-quarantine (TTIQ) strategy - is one of the cornerstone measures of…

Populations and Evolution · Quantitative Biology 2024-03-14 Julian Heidecke , Jan Fuhrmann , Maria Vittoria Barbarossa