Network-Driven Global Stability Analysis: SVIRS Epidemic Model

An epidemic Susceptible-Vaccinated-Infected-Removed-Susceptible (SVIRS) model is presented on a weighted-undirected network with graph Laplacian diffusion. Disease-free equilibrium always exists while the existence and uniqueness of endemic equilibrium have been shown. When the basic reproduction number is below unity, the disease-free equilibrium is asymptotically globally stable. The endemic equilibrium is asymptotically globally stable if the basic reproduction number is above unity. Numerical analysis is illustrated with a road graph of the state of Minnesota. The effect of all important model parameters has been discussed.