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Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

Computer Vision and Pattern Recognition · Computer Science 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

Optical Coherence Tomography allows ophthalmologist to obtain cross-section imaging of eye retina. Assisted with digital image analysis methods, effective disease detection could be performed. Various methods exist to extract feature from…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Kuntoro Adi Nugroho

Optical coherence tomography (OCT) scanning is useful in detecting various retinal diseases. However, there are not enough ophthalmologists who can diagnose retinal OCT images in much of the world. To provide OCT screening inexpensively and…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Ayaka Suzuki , Yoshiro Suzuki

Purpose: To assess whether a generative adversarial network (GAN) could synthesize realistic optical coherence tomography (OCT) images that satisfactorily serve as the educational images for retinal specialists and the training datasets for…

Medical Physics · Physics 2020-06-02 Ce Zheng , Xiaolin Xie , Kang Zhou , Bang Chen , Jili Chen , Haiyun Ye , Wen Li , Tong Qiao , Shenghua Gao , Jianlong Yang , Jiang Liu

Purpose: This study explores the feasibility of using generative machine learning (ML) to translate Optical Coherence Tomography (OCT) images into Optical Coherence Tomography Angiography (OCTA) images, potentially bypassing the need for…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Rashadul Hasan Badhon , Atalie Carina Thompson , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam

Oral Cavity Squamous Cell Carcinoma (OCSCC) is the most common type of head and neck cancer. Due to the subtle nature of its early stages, deep and hidden areas of development, and slow growth, OCSCC often goes undetected, leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Vishal Manikanden , Aniketh Bandlamudi , Daniel Haehn

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

Quantitative Methods · Quantitative Biology 2021-12-16 David Le , Minhaj Alam , Cham Yao , Jennifer I. Lim , R. V. P. Chan , Devrim Toslak , Xincheng Yao

Optic nerve head (ONH) detection has been a crucial area of study in ophthalmology for years. However, the significant discrepancy between fundus image datasets, each generated using a single type of fundus camera, poses challenges to the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Jiayi Wang , Yi-An Mao , Xiaoyu Ma , Sicen Guo , Yuting Shao , Xiao Lv , Wenting Han , Mark Christopher , Linda M. Zangwill , Yanlong Bi , Rui Fan

Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Sharif Amit Kamran , Sourajit Saha , Ali Shihab Sabbir , Alireza Tavakkoli

Automated optic disc (OD) and optic cup (OC) segmentation in fundus images is relevant to efficiently measure the vertical cup-to-disc ratio (vCDR), a biomarker commonly used in ophthalmology to determine the degree of glaucomatous optic…

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed

Multimodal information is frequently available in medical tasks. By combining information from multiple sources, clinicians are able to make more accurate judgments. In recent years, multiple imaging techniques have been used in clinical…

Glaucoma is a leading cause of irreversible blindness, but early detection can significantly improve treatment outcomes. Traditional diagnostic methods are often invasive and require specialized equipment. In this work, we present a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Rishiraj Paul Chowdhury , Nirmit Shekar Karkera

Optical coherence tomography (OCT), a commonly used retinal imaging modality, plays a central role in retinal disease diagnosis by providing high-resolution visualization of retinal layers. While deep learning (DL) has achieved expert-level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tienyu Chang , Tianhao Li , Ruogu Fang , Jiang Bian , Yu Huang

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-11-03 Aized Amin Soofi , Fazal-e-Amin

Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Shuo Chen , Da Ma , Sieun Lee , Timothy T. L. Yu , Gavin Xu , Donghuan Lu , Karteek Popuri , Myeong Jin Ju , Marinko V. Sarunic , Mirza Faisal Beg

Optical coherence tomography (OCT) is a popular modality in ophthalmology and is also used intravascularly. Our interest in this work is OCT in the context of airway abnormalities in infants and children where the high resolution of OCT and…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Yining Jiao , Amy Oldenburg , Yinghan Xu , Srikamal Soundararajan , Carlton Zdanski , Julia Kimbell , Marc Niethammer

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina
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