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With the advancement of powerful image processing and machine learning techniques, CAD has become ever more prevalent in all fields of medicine including ophthalmology. Since optic disc is the most important part of retinal fundus image for…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Muhammad Naseer Bajwa , Muhammad Imran Malik , Shoaib Ahmed Siddiqui , Andreas Dengel , Faisal Shafait , Wolfgang Neumeier , Sheraz Ahmed

This study introduces the Hybrid Multi-modal VGG (HM-VGG) model, a cutting-edge deep learning approach for the early diagnosis of glaucoma. The HM-VGG model utilizes an attention mechanism to process Visual Field (VF) data, enabling the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Junliang Du , Yiru Cang , Tong Zhou , Jiacheng Hu , Weijie He

Glioma is a common malignant brain tumor with distinct survival among patients. The isocitrate dehydrogenase (IDH) gene mutation provides critical diagnostic and prognostic value for glioma. It is of crucial significance to non-invasively…

Image and Video Processing · Electrical Eng. & Systems 2021-09-13 Yiran Wei , Yonghao Li , Xi Chen , Carola-Bibiane Schönlieb , Chao Li , Stephen J. Price

Optical Coherence Tomography (OCT) is a vital imaging modality for diagnosing and monitoring retinal diseases. However, OCT images are inherently degraded by speckle noise, which obscures fine details and hinders accurate interpretation.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Botond Fazekas , Thomas Pinetz , Guilherme Aresta , Taha Emre , Hrvoje Bogunovic

Accurate diagnosis of glaucoma is challenging, as early-stage changes are subtle and often lack clear structural or appearance cues. Most existing approaches rely on a single modality, such as fundus or optical coherence tomography (OCT),…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhiwei Wang , Yuxing Li , Meilu Zhu , Defeng He , Edmund Y. Lam

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Jiaxuan Li , Peiyao Jin , Jianfeng Zhu , Haidong Zou , Xun Xu , Min Tang , Minwen Zhou , Yu Gan , Jiangnan He , Yuye Ling , Yikai Su

Glaucoma is the second leading cause of blindness all over the world, with approximately 60 million cases reported worldwide in 2010. If undiagnosed in time, glaucoma causes irreversible damage to the optic nerve leading to blindness. The…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Artem Sevastopolsky

Retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) are promising tools for the (early) diagnosis of Alzheimer's disease (AD). These non-invasive imaging techniques are cost-effective and more…

Image and Video Processing · Electrical Eng. & Systems 2022-09-09 Yasemin Turkan , F. Boray Tek

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

To establish the tissue regions necessary to accurately represent the mechanics of the optic nerve head (ONH), imaging data of the ONH from 2 healthy subjects were used to create in vivo subject-specific eye mechanical models considering…

Medical Physics · Physics 2025-05-01 Soumaya Ouhsousou , Lucy Q. Shen , Chhavi Saini , Amin Pourasghar , Mengyu Wang , John C. Brigham

The Convolutional Neural Network (CNN) has shown impressive performance in image classification because of its strong learning capabilities. However, it demands a substantial and balanced dataset for effective training. Otherwise, networks…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Arun Kunwar , Dibakar Raj Pant , Jukka Heikkonen , Rajeev Kanth

Optical Coherence Tomography (OCT) is an imaging modality that has been widely adopted for visualizing corneal, retinal and limbal tissue structure with micron resolution. It can be used to diagnose pathological conditions of the eye, and…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jiahong Ouyang , Tejas Sudharshan Mathai , Kira Lathrop , John Galeotti

Purpose: To remove retinal shadows from optical coherence tomography (OCT) images of the optic nerve head(ONH). Methods:2328 OCT images acquired through the center of the ONH using a Spectralis OCT machine for both eyes of 13 subjects were…

Goal: In this work, we develop a robust, extensible tool to automatically and accurately count retinal ganglion cell axons in images of optic nerve tissue from various animal models of glaucoma. Methods: The U-Net convolutional neural…

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Samuel T. M. Ball

Glaucoma is an irreversible ocular disease and is the second leading cause of visual disability worldwide. Slow vision loss and the asymptomatic nature of the disease make its diagnosis challenging. Early detection is crucial for preventing…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Gyanendar Manohar , Ruairi O'Reilly

Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a…

In this paper, we have proposed a new glaucoma classification approach that employs a wavelet neural network (WNN) on optimally enhanced retinal images features. To avoid tedious and error prone manual analysis of retinal images by…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 N. Krishna Santosh , Soubhagya Sankar Barpanda
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