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In this study, a density-on-density regression model is introduced, where the association between densities is elucidated via a warping function. The proposed model has the advantage of a being straightforward demonstration of how one…

Methodology · Statistics 2023-07-10 Yi Zhao , Abhirup Datta , Bohao Tang , Vadim Zipunnikov , Brian S. Caffo

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

For the nonparametric regression models with covariates contaminated with normal measurement errors, this paper proposes an extrapolation algorithm to estimate the nonparametric regression functions. By applying the conditional expectation…

Methodology · Statistics 2021-07-28 Weixing Song , Kanwal Ayub , Jianhong Shi

Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Huy-Dung Nguyen , Michaël Clément , Vincent Planche , Boris Mansencal , Pierrick Coupé

Convolutional neural networks have shown impressive abilities in many applications, especially those related to the classification tasks. However, for the regression problem, the abilities of convolutional structures have not been fully…

Machine Learning · Computer Science 2023-01-23 Zhiying Fang , Guang Cheng

Deep neural networks are powerful tools to model observations over time with non-linear patterns. Despite the widespread use of neural networks in such settings, most theoretical developments of deep neural networks are under the assumption…

Machine Learning · Statistics 2022-10-24 Mingliang Ma , Abolfazl Safikhani

Nonlinear function estimation is core to modern machine learning applications. In this paper, to perform nonlinear function estimation, we reduce a nonlinear inverse problem to a linear one using a polynomial kernel expansion. These kernels…

Information Theory · Computer Science 2019-10-02 Hangjin Liu , You , Zhou , Ahmad Beirami , Dror Baron

Deep learning, a cutting-edge machine learning approach, outperforms traditional machine learning in identifying intricate structures in complex high-dimensional data, particularly in the domain of healthcare. This study focuses on…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Nida Nasir , Muneeb Ahmed , Neda Afreen , Mustafa Sameer

In this paper, we establish minimax optimal rates of convergence for prediction in a semi-functional linear model that consists of a functional component and a less smooth nonparametric component. Our results reveal that the smoother…

Statistics Theory · Mathematics 2021-11-01 Keli Guo , Jun Fan , Lixing Zhu

Functional data such as curves and surfaces have become more and more common with modern technological advancements. The use of functional predictors remains challenging due to its inherent infinite-dimensionality. The common practice is to…

Statistics Theory · Mathematics 2023-01-31 Dengdeng Yu , Matthew Pietrosanu , Ivan Mizera , Bei Jiang , Linglong Kong , Wei Tu

We present a new active learning algorithm based on nonparametric estimators of the regression function. Our investigation provides probabilistic bounds for the rates of convergence of the generalization error achievable by proposed method…

Statistics Theory · Mathematics 2011-11-03 Stanislav Minsker

In functional data analysis (FDA), covariance function is fundamental not only as a critical quantity for understanding elementary aspects of functional data but also as an indispensable ingredient for many advanced FDA methods. This paper…

Methodology · Statistics 2017-01-24 Raymond K. W. Wong , Xiaoke Zhang

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Quantitative Methods · Quantitative Biology 2020-10-07 Sema Candemir , Xuan V. Nguyen , Luciano M. Prevedello , Matthew T. Bigelow , Richard D. White , Barbaros S. Erdal

Ensemble learning use multiple algorithms to obtain better predictive performance than any single one of its constituent algorithms could. With growing popularity of deep learning, researchers have started to ensemble them for various…

Machine Learning · Computer Science 2019-05-31 Ning An , Huitong Ding , Jiaoyun Yang , Rhoda Au , Ting Fang Alvin Ang

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Yihao Lin , Ximeng Li , Yan Zhang , Jinshan Tang

Measuring transient functional connectivity is an important challenge in Electroencephalogram (EEG) research. Here, the rich potential for insightful, discriminative information of brain activity offered by high temporal resolution is…

Neurons and Cognition · Quantitative Biology 2025-02-11 Om Roy , Yashar Moshfeghi , Agustin Ibanez , Francisco Lopera , Mario A Parra , Keith M Smith

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

Machine Learning · Computer Science 2021-01-13 Alexander Lavin
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