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The goal of nonparametric regression is to recover an underlying regression function from noisy observations, under the assumption that the regression function belongs to a pre-specified infinite dimensional function space. In the online…

Methodology · Statistics 2021-04-05 Tianyu Zhang , Noah Simon

A deep neural network for classification tasks is essentially consist of two components: feature extractors and function approximators. They usually work as an integrated whole, however, improvements on any components can promote the…

Machine Learning · Computer Science 2021-12-06 Chi-Chun Zhou , Hai-Long Tu , Yue-Jie Hou , Zhen Ling , Yi Liu , Jian Hua

Magnetic Resonance Imaging (MRI) provides detailed structural information, while functional MRI (fMRI) captures temporal brain activity. In this work, we present a multimodal deep learning framework that integrates MRI and fMRI for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Anima Kujur , Zahra Monfared

Functional Magnetic Resonance Imaging (fMRI) is commonly utilized to study human brain activity, including abnormal functional properties related to neurodegenerative diseases. This study aims to investigate the differences in the…

Neurons and Cognition · Quantitative Biology 2023-05-17 Yongcheng Yao

Alzheimer's disease is one of the most common types of neurodegenerative disease, characterized by the accumulation of amyloid-beta plaque and tau tangles. Recently, deep learning approaches have shown promise in Alzheimer's disease…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Gia Minh Hoang , Youngjoo Lee , Jae Gwan Kim

In the recent years there have been a number of studies that applied deep learning algorithms to neuroimaging data. Pipelines used in those studies mostly require multiple processing steps for feature extraction, although modern…

Computer Vision and Pattern Recognition · Computer Science 2017-01-25 Sergey Korolev , Amir Safiullin , Mikhail Belyaev , Yulia Dodonova

Deep neural networks (DNN) has received increasing attention in machine learning applications in the last several years. Recently, a non-asymptotic error bound has been developed to measure the performance of the fully connected DNN…

Machine Learning · Statistics 2024-05-15 Kejin Wu , Dimitris N. Politis

Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated…

Image and Video Processing · Electrical Eng. & Systems 2019-08-22 Taeho Jo , Kwangsik Nho , Andrew J. Saykin

Motivated by modeling and analysis of mass-spectrometry data, a semi- and nonparametric model is proposed that consists of a linear parametric component for individual location and scale and a nonparametric regression function for the…

Methodology · Statistics 2013-05-08 Weiping Ma , Yang Feng , Kani Chen , Zhiliang Ying

Dementia is a growing problem as our society ages, and detection methods are often invasive and expensive. Recent deep-learning techniques can offer a faster diagnosis and have shown promising results. However, they require large amounts of…

Computation and Language · Computer Science 2022-07-19 Anna Hlédiková , Dominika Woszczyk , Alican Akman , Soteris Demetriou , Björn Schuller

We study the semiparametric efficient estimation of a class of linear functionals in settings where a complete multivariate dataset is supplemented by additional datasets recording subsets of the variables of interest. These datasets are…

Statistics Theory · Mathematics 2025-06-19 Thomas B. Berrett

Being the most commonly known neurodegeneration, Alzheimer's Disease (AD) is annually diagnosed in millions of patients. The present medical scenario still finds the exact diagnosis and classification of AD through neuroimaging data as a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Pavan Kumar S , Aravintakshan S A

This work proposes a way to detect the wandering activity of Alzheimer's patients from path data collected from non-intrusive indoor sensors around the house. Due to the lack of adequate data, we've manually generated a dataset of 220 paths…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Rafael F. C. Oliveira , Fabio Barreto , Raphael Abreu

Functional depth is the functional data analysis technique that orders a functional data set. Unlike the case of data on the real line, defining this order is non-trivial, and particularly, with functional data, there are a number of…

Methodology · Statistics 2022-06-29 Alicia Nieto-Reyes , John A. D. Aston

This paper is motivated by the joint analysis of genetic, imaging, and clinical (GIC) data collected in the Alzheimer's Disease Neuroimaging Initiative (ADNI) study. We propose a regression framework based on partially functional linear…

Methodology · Statistics 2023-02-23 Ting Li , Yang Yu , J. S. Marron , Hongtu Zhu

We focus on semiparametric regression that has played a central role in statistics, and exploit the powerful learning ability of deep neural networks (DNNs) while enabling statistical inference on parameters of interest that offers…

Statistics Theory · Mathematics 2025-04-29 Shunxing Yan , Ziyuan Chen , Fang Yao

In the functional linear regression model, many methods have been proposed and studied to estimate the slope function while the functional predictor was observed in the entire domain. However, works on functional linear regression models…

Methodology · Statistics 2021-12-21 Yafei Wang , Tingyu Lai , Bei Jiang , Linglong Kong , Zhongzhan Zhang

We provide a theoretical foundation for non-parametric estimation of functions of random variables using kernel mean embeddings. We show that for any continuous function $f$, consistent estimators of the mean embedding of a random variable…

Machine Learning · Statistics 2018-06-04 Carl-Johann Simon-Gabriel , Adam Ścibior , Ilya Tolstikhin , Bernhard Schölkopf

A plethora of deep learning models have been developed for the task of Alzheimer's disease classification from brain MRI scans. Many of these models report high performance, achieving three-class classification accuracy of up to 95%.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Ziqiang Guan , Ritesh Kumar , Yi Ren Fung , Yeahuay Wu , Madalina Fiterau

In the last decade, computer-aided early diagnostics of Alzheimer's Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research. Some recent studies have shown promising results in the AD…

Computer Vision and Pattern Recognition · Computer Science 2018-09-12 Alexander Khvostikov , Karim Aderghal , Andrey Krylov , Gwenaelle Catheline , Jenny Benois-Pineau