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Group testing is utilized in the case when we want to find a few defectives among large amount of items. Testing n items one by one requires n tests, but if the ratio of defectives is small, group testing is an efficient way to reduce the…

Computation · Statistics 2024-05-16 Hiroyasu Matsushima , Yusuke Tajima , Xiao-Nan Lu , Masakazu Jimbo

Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative rate is projected to be as high as 30% and test results can take some time to obtain. X-ray machines are widely available and provide images for…

Image and Video Processing · Electrical Eng. & Systems 2020-05-22 Lawrence O. Hall , Rahul Paul , Dmitry B. Goldgof , Gregory M. Goldgof

We analyze the effect of using a screening CT-scan for evaluation of potential COVID-19 infections in order to isolate and perform contact tracing based upon a viral pneumonia diagnosis. RT-PCR is then used for continued isolation based…

Populations and Evolution · Quantitative Biology 2020-06-04 Chen Shen , Ron Mark , Nolan J. Kagetsu , Anton S. Becker , Yaneer Bar-Yam

Large-scale testing is considered key to assess the state of the current COVID-19 pandemic. Yet, the link between the reported case numbers and the true state of the pandemic remains elusive. We develop mathematical models based on…

Applications · Statistics 2021-02-04 Michel Besserve , Simon Buchholz , Bernhard Schölkopf

COVID-19 testing, the cornerstone for effective screening and identification of COVID-19 cases, remains paramount as an intervention tool to curb the spread of COVID-19 both at local and national levels. However, the speed at which the…

The Coronavirus disease 2019 (COVID-19) has affected several million people. With the outbreak of the epidemic, many researchers are devoting themselves to the COVID-19 screening system. The standard practices for rapid risk screening of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Yanwei Fu , Feng Li , Wenxuan Wang , Haicheng Tang , Xuelin Qian , Mengwei Gu , Xiangyang Xue

Motivated by the current COVID-19 health-crisis, we examine the task of baseline subtraction for quantitative polymerase chain-reaction (qPCR) measurements. In particular, we present an algorithm that leverages information obtained from…

Quantitative Methods · Quantitative Biology 2020-04-14 Paul N. Patrone , Anthony J. Kearsley , Erica L. Romsos , Peter M. Vallone

Pooled testing is widely used for screening for viral or bacterial infections with low prevalence when individual testing is not cost-efficient. Pooled testing with qualitative assays that give binary results has been well-studied. However,…

Methodology · Statistics 2020-11-03 Tao Liu , Joseph W Hogan , Wanning Su , Yizhen Xu , Michael J Daniels , Kantor Rami

Multiple testing problems are a staple of modern statistical analysis. The fundamental objective of multiple testing procedures is to reject as many false null hypotheses as possible (that is, maximize some notion of power), subject to…

Methodology · Statistics 2020-11-30 Saharon Rosset , Ruth Heller , Amichai Painsky , Ehud Aharoni

This paper is a short extension of our previous paper [arXiv:2004.06033] about the use of the Test-Negative design to study risk factors for COVID-19 [See: PubMed and ArXiv reference below] Reason for the extension is that the conditions…

Populations and Evolution · Quantitative Biology 2021-06-08 Jan P Vandenbroucke , Elizabeth B Brickley , Christina M. J. E. Vandenbroucke-Grauls , Neil Pearce

Physicians taking care of patients with coronavirus disease (COVID-19) have described different changes in routine blood parameters. However, these changes, hinder them from performing COVID-19 diagnosis. We constructed a machine learning…

With the increasing spread of COVID-19, it is important to systematically test more and more people. The current strategy for test-kit allocation is mostly rule-based, focusing on individuals having (a) symptoms for COVID-19, (b) travel…

Artificial Intelligence · Computer Science 2020-04-07 Arpita Biswas , Shruthi Bannur , Prateek Jain , Srujana Merugu

The COVID-19 pandemic has had devastating effects on the well-being of the global population. The pandemic has been so prominent partly due to the high infection rate of the virus and its variants. In response, one of the most effective…

Image and Video Processing · Electrical Eng. & Systems 2021-05-06 Jianxing Zhang , Pengcheng Xi , Ashkan Ebadi , Hilda Azimi , Stephane Tremblay , Alexander Wong

Test-negative designs with added controls have recently been proposed to study COVID-19. An individual is test-positive or test-negative accordingly if they took a test for a disease but tested positive or tested negative. Adding a control…

Methodology · Statistics 2020-05-15 Bikram Karmakar , Dylan Small

Governments and public health authorities use seroprevalence studies to guide responses to the COVID-19 pandemic. Seroprevalence surveys estimate the proportion of individuals who have detectable SARS-CoV-2 antibodies. However, serologic…

Applications · Statistics 2022-11-11 Samuel P. Rosin , Bonnie E. Shook-Sa , Stephen R. Cole , Michael G. Hudgens

In light of the continuous transmission and evolution of SARS-CoV-2 coupled with a significant decline in clinical testing, there is a pressing need for scalable, cost-effective, long-term, passive surveillance tools to effectively monitor…

Computer audition (CA) has been demonstrated to be efficient in healthcare domains for speech-affecting disorders (e.g., autism spectrum, depression, or Parkinson's disease) and body sound-affecting abnormalities (e. g., abnormal bowel…

Sound · Computer Science 2020-12-10 Kun Qian , Bjorn W. Schuller , Yoshiharu Yamamoto

The problem of Group Testing is to identify defective items out of a set of objects by means of pool queries of the form "Does the pool contain at least a defective?". The aim is of course to perform detection with the fewest possible…

Statistical Mechanics · Physics 2009-11-13 M. Mézard , M. Tarzia , C. Toninelli

The coronavirus pandemic has rapidly evolved into an unprecedented crisis. The susceptible-infectious-removed (SIR) model and its variants have been used for modeling the pandemic. However, time-independent parameters in the classical…

Populations and Evolution · Quantitative Biology 2020-09-09 Hyokyoung G. Hong , Yi Li

Large scale disease screening is a complicated process in which high costs must be balanced against pressing public health needs. When the goal is screening for infectious disease, one approach is group testing in which samples are…

Applications · Statistics 2021-03-02 Gregory Haber , Yaakov Malinovsky , Paul S. Albert