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Related papers: Quantitative Diffractometric Biosensing

200 papers

Accurate, label-free quantification of multiple analytes in complex biological media remains a major challenge due to limited multiplexing, signal cross-correlations, and inconsistency across sensor samples and measurement runs. We…

While the mathematical foundations of score-based generative models are increasingly well understood for unconstrained Euclidean spaces, many practical applications involve data restricted to bounded domains. This paper provides a…

Statistics Theory · Mathematics 2026-03-26 Asbjørn Holk , Claudia Strauch , Lukas Trottner

We configure and analyze a nanostructured device that hybridizes grating modes and surface plasmon resonances. The model uses an effective index of refraction that considers the volume fraction of the involved materials, and the propagation…

Our growing ability to tailor healthcare to the needs of individuals has the potential to transform clinical treatment. However, the measurement of multiple biomarkers to inform clinical decisions requires rapid, effective, and affordable…

High-fidelity spectrum cartography is pivotal for spectrum management and wireless situational awareness, yet it remains a challenging ill-posed inverse problem due to the sparsity and irregularity of observations. Furthermore, existing…

Information Theory · Computer Science 2025-12-24 Yuntong Gu , Xiangming meng , Zhiyuan Lin , Sheng Wu , Linling Kuang

Decentralized diagnostic testing that is accurate, portable, quantitative, and capable of making multiple simultaneous measurements of different biomarkers at the point-of-need remains an important unmet need in the post-pandemic world.…

Optical metasurface has brought a revolution in label-free molecular sensing, attracting extensive attention. Currently, such sensing approaches are being designed to respond to peak wavelengths with a higher Q factor in the visible and…

We demonstrate novel instrumentation for spontaneous Raman spectroscopy in biofluids, enabling development of a portable, automated, reliable diagnostics technique requiring minimal operator expertise to quantify disease markers. Label-free…

Biological Physics · Physics 2021-05-27 Emily E. Storey , Duxuan Wu , Amr S. Helmy

Wavefront sensing with a thin diffuser has emerged as a potential low-cost alternative to a lenslet array for aberrometry. Diffuser wavefront sensors (DWS) have previously relied on tracking speckle displacement and consequently require…

Optics · Physics 2019-01-01 Gregory N. McKay , Faisal Mahmood , Nicholas J. Durr

Microwave reflectance probed photoconductivity (or $\mu$-PCD) measurement represents a contactless and non-invasive method to characterize impurity content in semiconductors. Major drawbacks of the method include a difficult separation of…

Applied Physics · Physics 2019-12-18 B. Gyüre-Garami , B. Blum , O. Sági , A. Bojtor , S. Kollarics , G. Csősz , B. G. Márkus , J. Volk , F. Simon

We demonstrate the realization of refractometric measurements relying on the study of the transmission spectrum of filled capillary fibers. In this method, the fiber is filled with a material with a lower refractive index than that of the…

Camouflaged object detection is a challenging task that aims to identify objects that are highly similar to their background. Due to the powerful noise-to-image denoising capability of denoising diffusion models, in this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Zhennan Chen , Rongrong Gao , Tian-Zhu Xiang , Fan Lin

We introduce a novel reflection-mode diffraction tomography technique that enables simultaneous recovery of forward and backward scattering information for high-resolution 3D refractive index reconstruction. Our technique works by imaging a…

Optics · Physics 2025-02-12 Tongyu Li , Jiabei Zhu , Yi Shen , Lei Tian

Coherent Diffractive Imaging is a lensless technique that allows imaging of matter at a spatial resolution not limited by lens aberrations. This technique exploits the measured diffraction pattern of a coherent beam scattered by periodic…

Computational Physics · Physics 2025-08-27 Alessandro Colombo , Davide Emilio Galli , Liberato De Caro , Francesco Scattarella , Elvio Carlino

Bi-CamoDiffusion is introduced, an evolution of the CamoDiffusion framework for camouflaged object detection. It integrates edge priors into early-stage embeddings via a parameter-free injection process, which enhances boundary sharpness…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Patricia L. Suarez , Leo Thomas Ramos , Angel D. Sappa

As a label-free imaging technique, quantitative phase imaging (QPI) provides optical path length information of transparent specimens for various applications in biology, materials science, and engineering. Multispectral QPI measures…

Optics · Physics 2023-08-29 Che-Yung Shen , Jingxi Li , Deniz Mengu , Aydogan Ozcan

We consider refractive index sensing with optical bounds states in the continuum (BICs) in dielectric gratings. Applying a perturbative approach we derived the differential sensitivity and the figure of merit of a sensor operating in the…

We demonstrate aqueous refractive index sensing with 15 to 30 {\mu}m diameter silicon nitride microdisk resonators to detect small concentrations of Li salt. A dimpled-tapered fiber is used to couple 780 nm visible light to the microdisks,…

Mesoscale and Nanoscale Physics · Physics 2015-04-06 C. Doolin , P. Doolin , B. C. Lewis , J. P. Davis

In this work, a refractive index (RI) sensor with an effective integration of colorimetric detection and optical sensing capabilities has been developed. Colorimetric detection relies on the sensitivity of the structural color of photonic…

Optics · Physics 2021-07-09 Cheng Fang , Qingqing Shang , Fen Tang , Songlin Yang , Ran Ye

Significance: Diffuse in-vivo Flow Cytometry (DiFC) is an emerging fluorescence sensing method to non-invasively detect labeled circulating cells in-vivo. However, due to Signal-to-Noise Ratio (SNR) constraints largely attributed to…

Medical Physics · Physics 2023-08-04 Giles Blaney , Fernando Ivich , Angelo Sassaroli , Mark Niedre , Sergio Fantini