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Related papers: Quantitative Diffractometric Biosensing

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Optical diffraction tomography (ODT) has emerged as a powerful label-free three-dimensional (3D) bioimaging techniques for observing living cells and thin tissue layers. We report a new reflection-mode ODT (rODT) method for imaging thick…

Geometric information in the normalized digital surface models (nDSM) is highly correlated with the semantic class of the land cover. Exploiting two modalities (RGB and nDSM (height)) jointly has great potential to improve the segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Zhitong Xiong , Sining Chen , Yi Wang , Lichao Mou , Xiao Xiang Zhu

Many important phenomena in quantum devices are dynamic, meaning that they cannot be studied using time-averaged measurements alone. Experiments that measure such transient effects are collectively known as fast readout. One of the most…

We numerically design a hybrid plasmonic dielectric refractive index biosensor comprising ametal insulator metal (MIM) bus waveguide evanescently coupled to a silicon core resonator. The geometry is optimized with a genetic algorithm (GA)…

Instrumentation and Detectors · Physics 2025-08-27 Alireza Khalilian , Hima Nikafshan Rad

Diffraction microtomography in coherent light is foreseen as a promising technique to image transparent living samples in three dimensions without staining. Contrary to conventional microscopy with incoherent light, which gives…

Optics · Physics 2009-11-13 Stanislas Vertu , Jean-Jacques Delaunay , Olivier Haeberle

Recent advances in the field of attosecond science hold the promise of tracking electronic processes at the shortest space and time scales. Imaging methods that combine attosecond temporal with nanometer spatial resolution are currently out…

Non-invasive morphological assessment is the cornerstone of oocyte and embryo selection in assisted reproductive technology, yet clinical practice remains limited by two-dimensional, qualitative microscopy. While three-dimensional (3D)…

Imaging techniques such as functional near-infrared spectroscopy (fNIRS) and diffuse optical tomography (DOT) achieve deep, non-invasive sensing in turbid media, but they are constrained by the photon budget. Wavefront shaping (WFS) can…

Optics · Physics 2026-04-21 Pablo Jara , Arthur Goetschy , Hui Cao , Alexey Yamilov

Wavy dielectric grating hosts bound states in the continuum (BICs) at nonzero Bloch wave number. For oblique incident optical field with parameters near to the BICs, the reflectance spectrum exhibits ultra-sharp Fano line shape, and the…

Optics · Physics 2024-05-17 Ma Luo , Feng Wu

Machine learning tasks involving biomedical signals frequently grapple with issues such as limited data availability, imbalanced datasets, labeling complexities, and the interference of measurement noise. These challenges often hinder the…

Signal Processing · Electrical Eng. & Systems 2024-01-30 Xiaomin Li , Mykhailo Sakevych , Gentry Atkinson , Vangelis Metsis

We proposed a novel approach to coherent imaging of dynamic samples. The inter-frame similarity of the sample's local structures is found to be a powerful constraint in phasing a sequence of diffraction patterns. We devised a new image…

Optics · Physics 2024-07-11 Pengju Sheng , Fucai Zhang

We present an algorithm for coherent diffractive imaging with phaseless measurements. It treats the forward model as a combination of coherent and incoherent waves. The algorithm reconstructs absorption and phase contrast that quantifies…

Computational Physics · Physics 2022-08-25 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

Reflection phase imaging provides label-free, high-resolution characterization of biological samples, typically using interferometric-based techniques. Here, we investigate reflection phase microscopy from intensity-only measurements under…

Quantitative Methods · Quantitative Biology 2019-12-18 Alex Matlock , Anne Sentenac , Patrick C. Chaumet , Ji Yi , Lei Tian

The characterization of white blood cells (WBCs) is crucial for blood analyses and disease diagnoses. However, current standard techniques rely on cell labeling, a process which imposes significant limitations. Here we present…

Biological Physics · Physics 2015-05-12 Jonghee Yoon , Kyoohyun Kim , HyunJoo Park , Chulhee Choi , Seongsoo Jang , YongKeun Park

Glass is a prevalent material among solid objects in everyday life, yet segmentation methods struggle to distinguish it from opaque materials due to its transparency and reflection. While it is known that human perception relies on boundary…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Tuan-Anh Vu , Hai Nguyen-Truong , Ziqiang Zheng , Binh-Son Hua , Qing Guo , Ivor Tsang , Sai-Kit Yeung

Image degradation impedes our ability to extract information from astronomical observations. One factor contributing to this degradation is ``dome seeing", the reduction in image quality due to variations in the index of refraction within…

Instrumentation and Methods for Astrophysics · Physics 2023-11-08 Ali Kurmus , Elana Urbach , Christopher W. Stubbs

Studies of biological solutions require high measurement accuracy, the ability to detect low changes in substance concentration, and small amounts of the liquid under test. A microwave complex permittivity measurement technique based on a…

We have designed optical metasurfaces hosting high-quality factor quasi-bound state in the continuum (q-BIC) resonances for optical biosensing in flow. The unit cell of the metasurface contains two rectangular bars. An asymmetry factor is…

In this paper, we present a plasmonic refractometric sensor that works under normal incidence; allowing its integration on a fiber tip. The sensor's material and geometry exploit the large scattering cross-section given by high-contrast of…

Optics · Physics 2019-04-02 Elshorbagy , M. , Cuadrado , A. , Gonzalez , G. , Gonzalez F. J. , Alda , Javier

A modified weak measurement scheme, rotatory biased weak measurement, is proposed to significantly improve the sensitivity and resolution of the refractive index sensor on a total reflection structure. This method introduces an additional…

Quantum Physics · Physics 2022-04-25 Chongqi Zhou , Yang Xu , Xiaonan Zhang , Zhangyan Li , Tian Guan , Yonghong He , Yanhong Ji