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Accurate reconstruction of cardiac anatomy from sparse clinical images remains a major challenge in patient-specific modeling. While neural implicit functions have previously been applied to this task, their application to mapping…

Coronary artery bypass grafts (CABG) surgery is an invasive procedure performed to circumvent partial or complete blood flow blockage in coronary artery disease (CAD). In this work, we apply a numerical optimal flow control model to…

Numerical Analysis · Mathematics 2023-08-08 Zakia Zainib , Francesco Ballarin , Stephen Fremes , Piero Triverio , Laura Jiménez-Juan , Gianluigi Rozza

Interest in the application of engineering methods to problems in congenital heart disease has gained increased popularity over the past decade. The use of computational simulation to examine common clinical problems including single…

Medical Physics · Physics 2011-01-20 Irene Vignon Clementel , Alison L. Marsden , Jeffrey A. Feinstein

Although the heart has complex three-dimensional (3D) anatomy, conventional medical imaging with cardiac ultrasound relies on a series of 2D videos showing individual cardiac structures. 3D echocardiography is a developing modality that now…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Milos Vukadinovic , Hirotaka Ieki , Yuki Sahashi , David Ouyang , Bryan He

This work is dedicated to the simulation of full cycles of the electrical activity of the heart and the corresponding body surface potential. The model is based on a realistic torso and heart anatomy, including ventricles and atria. One of…

Medical Physics · Physics 2015-09-04 Elisa Schenone , Annabelle Collin , Jean-Frédéric Gerbeau

Myocardial infarction (MI) is one of the most prevalent cardiovascular diseases with associated clinical decision-making typically based on single-valued imaging biomarkers. However, such metrics only approximate the complex 3D structure…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Marcel Beetz , Yilong Yang , Abhirup Banerjee , Lei Li , Vicente Grau

Numerical simulations of cardiovascular mass transport pose significant challenges due to the wide range of P\'eclet numbers and backflow at Neumann boundaries. In this paper we present and discuss several numerical tools to address these…

Computational Physics · Physics 2020-06-24 Sabrina R. Lynch , Nitesh Nama , Zelu Xu , Christopher J. Arthurs , Onkar Sahni , C. Alberto Figueroa

Leveraging big data for patient care is promising in many medical fields such as cardiovascular health. For example, hemodynamic biomarkers like wall shear stress could be assessed from patient-specific medical images via machine learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Julian Suk , Jolanda J. Wentzel , Patryk Rygiel , Joost Daemen , Daniel Rueckert , Jelmer M. Wolterink

Accurate assessment of intraventricular blood flow is essential for evaluating hemodynamic conditions in patients supported by Left Ventricular Assist Devices (LVADs). However, clinical imaging is either incompatible with LVADs or yields…

Combining physics-based modeling with data-driven methods is critical to enabling the translation of computational methods to clinical use in cardiology. The use of rigorous differential equations combined with machine learning tools allows…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Elena Martinez , Beatrice Moscoloni , Matteo Salvador , Fanwei Kong , Mathias Peirlinck , Alison Lesley Marsden

3D printing has been widely adopted for clinical decision making and interventional planning of Congenital heart disease (CHD), while whole heart and great vessel segmentation is the most significant but time-consuming step in the model…

Image and Video Processing · Electrical Eng. & Systems 2019-07-15 Xiaowei Xu , Tianchen Wang , Dewen Zeng , Yiyu Shi , Qianjun Jia , Haiyun Yuan , Meiping Huang , Jian Zhuang

Fluid-structure interaction in the developing heart is an active area of research in developmental biology. However, investigation of heart dynamics is mostly limited to computational fluid dynamics simulations using heart wall structure…

Quantitative Methods · Quantitative Biology 2018-03-01 Vytautas Zickus , Jonathan M. Taylor

The bidomain model is widely used in electro-cardiology to simulate spreading of excitation in the myocardium and electrocardiograms. It consists of a system of two parabolic reaction diffusion equations coupled with an ODE system. Its…

Numerical Analysis · Mathematics 2017-12-06 Charles Pierre

4D Flow is an MRI sequence which allows acquisition of 3D images of the heart. The data is typically acquired volumetrically, so it must be reformatted to generate cardiac long axis and short axis views for diagnostic interpretation. These…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Matthieu Le , Jesse Lieman-Sifry , Felix Lau , Sean Sall , Albert Hsiao , Daniel Golden

In this study we present a novel computational model for unprecedented simulations of the whole cardiac electrophysiology. According to the heterogeneous electrophysiologic properties of the heart, the whole cardiac geometry is decomposed…

Medical Physics · Physics 2022-03-14 Giulio Del Corso , Roberto Verzicco , Francesco Viola

Phase-transition models are an important family of non-equilibrium continuum traffic flow models, offering properties like replicating complex traffic phenomena, maintaining anisotropy, and promising potentials for accommodating automated…

Numerical Analysis · Mathematics 2025-07-01 Shaoshuai Chu , Alexander Kurganov , Saeed Mohammadian , Zuduo Zheng

Background: Conventional cardiovascular magnetic resonance (CMR) in paediatric and congenital heart disease uses 2D, breath-hold, balanced steady state free precession (bSSFP) cine imaging for assessment of function and cardiac-gated,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Mark Wrobel , Michele Pascale , Tina Yao , Ruaraidh Campbell , Elena Milano , Michael Quail , Jennifer Steeden , Vivek Muthurangu

The aim of this study is to use image-processing techniques developed in the field of astrophysics as inspiration for a novel approach to the three-dimensional (3D) imaging of periprocedural medical data, with the intention of providing…

Medical Physics · Physics 2019-02-05 I. Brewis , J. A. McLaughlin

Accurate 3D representations of cardiac structures allow quantitative analysis of anatomy and function. In this work, we propose a method for reconstructing complete 3D cardiac shapes from segmentations of sparse planes in CT angiography…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Gino E. Jansen , Carolina Brás , R. Nils Planken , Mark J. Schuuring , Berto J. Bouma , Ivana Išgum

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink