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Related papers: Bidirectional Modeling and Analysis of Brain Aging…

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Synthetic longitudinal brain MRI simulates brain aging and would enable more efficient research on neurodevelopmental and neurodegenerative conditions. Synthetically generated, age-adjusted brain images could serve as valuable alternatives…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Anna Zapaishchykova , Benjamin H. Kann , Divyanshu Tak , Zezhong Ye , Daphne A. Haas-Kogan , Hugo J. W. L. Aerts

The process of integration of inputs from several sensory modalities in the human brain is referred to as multisensory integration. Age-related cognitive decline leads to a loss in the ability of the brain to conceive multisensory inputs.…

Signal Processing · Electrical Eng. & Systems 2023-05-02 Prerna Singh , Ayush Tripathi , Lalan Kumar , Tapan Kumar Gandhi

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

Neurons and Cognition · Quantitative Biology 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

Brain surface analysis is essential to neuroscience, however, the complex geometry of the brain cortex hinders computational methods for this task. The difficulty arises from a discrepancy between 3D imaging data, which is represented in…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Karthik Gopinath , Christian Desrosiers , Herve Lombaert

Estimating brain age from structural MRI has emerged as a powerful tool for characterizing normative and pathological aging. In this work, we explore contrastive learning as a scalable and robust alternative to L1-supervised approaches for…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Carlo Alberto Barbano , Benoit Dufumier , Edouard Duchesnay , Marco Grangetto , Pietro Gori

While utilizing machine learning models, one of the most crucial aspects is how bias and fairness affect model outcomes for diverse demographics. This becomes especially relevant in the context of machine learning for medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-10-19 Mahsa Dibaji , Neha Gianchandani , Akhil Nair , Mansi Singhal , Roberto Souza , Mariana Bento

Brain morphology is shaped by genetic and mechanical factors and is linked to biological development and diseases. Its fractal-like features, regional anisotropy, and complex curvature distributions hinder quantitative insights in medical…

Neurons and Cognition · Quantitative Biology 2025-09-09 Yingjie Zhao , Yicheng Song , Fan Xu , Zhiping Xu

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Alzheimer's Disease and normal aging are both characterized by brain atrophy. The question of whether AD-related brain atrophy represents accelerated aging or a neurodegeneration process distinct from that in normal aging remains…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Jingru Fu , Daniel Ferreira , Örjan Smedby , Rodrigo Moreno

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

The principled design and discovery of biologically- and physically-informed models of neuronal dynamics has been advancing since the mid-twentieth century. Recent developments in artificial intelligence (AI) have accelerated this progress.…

Neurons and Cognition · Quantitative Biology 2021-12-24 Mahta Ramezanian Panahi , Germán Abrevaya , Jean-Christophe Gagnon-Audet , Vikram Voleti , Irina Rish , Guillaume Dumas

Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…

Neurons and Cognition · Quantitative Biology 2025-02-13 Xinglin Zeng , Yiran Li , Lin Hua , Ruoxi Lu , Lucas Lemos Franco , Peter Kochunov , Shuo Chen , John A Detre , Ze Wang

Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability…

Neurons and Cognition · Quantitative Biology 2024-04-04 James K Ruffle , Robert J Gray , Samia Mohinta , Guilherme Pombo , Chaitanya Kaul , Harpreet Hyare , Geraint Rees , Parashkev Nachev

Brain aging trajectories differ between males and females, yet the genetic factors underlying these differences remain underexplored. Using structural MRI and genotyping data from 40,940 UK Biobank participants (aged 45-83), we computed…

Neurodegeneration, characterized by the progressive loss of neuronal structure or function, is commonly assessed in clinical practice through reductions in cortical thickness or brain volume, as visualized by structural MRI. While…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

In the field of neuroimaging, accurate brain age prediction is pivotal for uncovering the complexities of brain aging and pinpointing early indicators of neurodegenerative conditions. Recent advancements in self-supervised learning,…

We address the problem of single photo age progression and regression-the prediction of how a person might look in the future, or how they looked in the past. Most existing aging methods are limited to changing the texture, overlooking…

Computer Vision and Pattern Recognition · Computer Science 2020-07-27 Roy Or-El , Soumyadip Sengupta , Ohad Fried , Eli Shechtman , Ira Kemelmacher-Shlizerman

Face plays an important role in humans visual perception, and reconstructing perceived faces from brain activities is challenging because of its difficulty in extracting high-level features and maintaining consistency of multiple face…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Zihao Wang , Jing Zhao , Xuetong Ding , Hui Zhang

Aging is a highly complex and heterogeneous process that progresses at different rates across individuals, making biological age (BA) a more accurate indicator of physiological decline than chronological age. While previous studies have…

Genomics · Quantitative Biology 2025-10-24 Huifa Li , Feilong Tang , Haochen Xue , Yulong Li , Xinlin Zhuang , Bin Zhang , Eran Segal , Imran Razzak