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Counterfactual generation offers a principled framework for simulating hypothetical changes in medical imaging, with potential applications in understanding disease mechanisms and generating physiologically plausible data. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Pengwei Sun , Wei Peng , Lun Yu Li , Yixin Wang , Kilian M. Pohl

In this paper, we aim to automatically render aging faces in a personalized way. Basically, a set of age-group specific dictionaries are learned, where the dictionary bases corresponding to the same index yet from different dictionaries…

Computer Vision and Pattern Recognition · Computer Science 2015-10-23 Xiangbo Shu , Jinhui Tang , Hanjiang Lai , Luoqi Liu , Shuicheng Yan

We introduce graph normalizing flows: a new, reversible graph neural network model for prediction and generation. On supervised tasks, graph normalizing flows perform similarly to message passing neural networks, but at a significantly…

Machine Learning · Computer Science 2019-05-31 Jenny Liu , Aviral Kumar , Jimmy Ba , Jamie Kiros , Kevin Swersky

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

Artificial and biological systems may evolve similar computational solutions despite fundamental differences in architecture and learning mechanisms -- a form of convergent evolution. We demonstrate this phenomenon through large-scale…

Neurons and Cognition · Quantitative Biology 2025-07-04 Guobin Shen , Dongcheng Zhao , Yiting Dong , Qian Zhang , Yi Zeng

Although deep learning techniques show promising results for many neuroimaging tasks in research settings, they have not yet found widespread use in clinical scenarios. One of the reasons for this problem is that many machine learning…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Vibujithan Vigneshwaran , Erik Ohara , Matthias Wilms , Nils Forkert

Understanding human fetal neurodevelopment is of great clinical importance as abnormal development is linked to adverse neuropsychiatric outcomes after birth. Recent advances in functional Magnetic Resonance Imaging (fMRI) have provided new…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Xiangrui Li , Jasmine Hect , Moriah Thomason , Dongxiao Zhu

Normative modelling is an increasingly common statistical technique in neuroimaging that estimates population-level benchmarks in brain structure. It enables the quantification of individual deviations from expected distributions whilst…

Neurons and Cognition · Quantitative Biology 2025-10-21 Nida Alyas , Jonathan Horsley , Bethany Little , Peter N. Taylor , Yujiang Wang , Karoline Leiberg

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

Neurons and Cognition · Quantitative Biology 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

Computational facial models that capture properties of facial cues related to aging and kinship increasingly attract the attention of the research community, enabling the development of reliable methods for age progression, age estimation,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Markos Georgopoulos , Yannis Panagakis , Maja Pantic

Data-driven machine learning has made significant strides in medical image analysis. However, most existing methods are tailored to specific modalities and assume a particular resolution (often isotropic). This limits their generalizability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Peirong Liu , Ana Lawry Aguila , Juan E. Iglesias

A core goal of functional neuroimaging is to study how the environment is processed in the brain. The mainstream paradigm involves concurrently measuring a broad spectrum of brain responses to a small set of environmental features…

Neurons and Cognition · Quantitative Biology 2021-06-14 Pedro F. da Costa , Rianne Haartsen , Elena Throm , Luke Mason , Anna Gui , Robert Leech , Emily J. H. Jones

Over the past decade, studies of naturalistic language processing where participants are scanned while listening to continuous text have flourished. Using word embeddings at first, then large language models, researchers have created…

Computation and Language · Computer Science 2024-11-05 Laurent Bonnasse-Gahot , Christophe Pallier

Human brain development is rapid during infancy and early childhood. Many disease processes impair this development. Therefore, brain developmental age estimation (BDAE) is essential for all diseases affecting cognitive development. Brain…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Mahdieh Shabanian , Eugene C. Eckstein , Hao Chen , John P. DeVincenzo

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

Quantitative Methods · Quantitative Biology 2020-03-20 Shikuang Deng , Shi Gu

Recent studies have shown that multi-modeling methods can provide new insights into the analysis of brain components that are not possible when each modality is acquired separately. The joint representations of different modalities is a…

Neurons and Cognition · Quantitative Biology 2022-01-24 Jalal Mirakhorli

Morphological development into evolutionary patterns under structural instability is ubiquitous in living systems and often of vital importance for engineering structures. Here we propose a data-driven approach to understand and predict…

Pattern Formation and Solitons · Physics 2024-07-23 Yingjie Zhao , Zhiping Xu

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

Normalizing flows model complex probability distributions by combining a base distribution with a series of bijective neural networks. State-of-the-art architectures rely on coupling and autoregressive transformations to lift up invertible…

Machine Learning · Computer Science 2021-02-15 Antoine Wehenkel , Gilles Louppe

Naturalistic fMRI characterizes the brain as a dynamic predictive engine driven by continuous sensory streams. However, modeling the causal forward evolution in realistic neural simulation is impeded by the timescale mismatch between…

Neurons and Cognition · Quantitative Biology 2026-02-05 Xuanhua Yin , Runkai Zhao , Lina Yao , Weidong Cai
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