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Consider a two-type Moran population of size $N$ with selection and mutation, where the selective advantage of the fit individuals is amplified at extreme environmental conditions. Assume selection and mutation are weak with respect to $N$,…

Probability · Mathematics 2023-04-26 Fernando Cordero , Grégoire Véchambre

We study the common ancestor type distribution in a $2$-type Moran model with population size $N$, mutation and selection, and in the deterministic limit regime arising in the former when $N$ tends to infinity, without any rescaling of…

Probability · Mathematics 2018-04-05 Fernando Cordero

We consider the Moran model of population genetics with two types, mutation, and selection, and investigate the line of descent of a randomly-sampled individual from a contemporary population. We trace this ancestral line back into the…

Probability · Mathematics 2024-05-22 Ellen Baake , Enrico Di Gaspero , Fernando Cordero

We consider two versions of stochastic population models with mutation and selection. The first approach relies on a multitype branching process; here, individuals reproduce and change type (i.e., mutate) independently of each other,…

Populations and Evolution · Quantitative Biology 2009-02-19 E. Baake , R. Bialowons

We consider the Moran model in continuous time with two types, mutation, and selection. We concentrate on the ancestral line and its stationary type distribution. Building on work by Fearnhead (J. Appl. Prob. 39 (2002), 38-54) and Taylor…

Populations and Evolution · Quantitative Biology 2013-12-09 Sandra Kluth , Thiemo Hustedt , Ellen Baake

Motivated by the question of the impact of selective advantage in populations with skewed reproduction mechanims, we study a Moran model with selection. We assume that there are two types of individuals, where the reproductive success of…

Probability · Mathematics 2024-01-08 Adrián González Casanova , Noemi Kurt , José Luis Pérez

We review recent progress on ancestral processes related to mutation-selection models, both in the deterministic and the stochastic setting. We mainly rely on two concepts, namely, the killed ancestral selection graph and the pruned…

Probability · Mathematics 2020-03-17 Ellen Baake , Anton Wakolbinger

To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population…

Probability · Mathematics 2023-11-30 Alison M. Etheridge , Sophie Lemaire

We reconsider the deterministic haploid mutation-selection equation with two types. This is an ordinary differential equation that describes the type distribution (forward in time) in a population of infinite size. This paper establishes…

Probability · Mathematics 2020-09-25 Ellen Baake , Fernando Cordero , Sebastian Hummel

We consider a population of N individuals, whose dynamics through time is represented by a biparental Moran model with two types: an advantaged type and a disadvantaged type. The advantage is due to a mutation, transmitted in a Mendelian…

Probability · Mathematics 2024-05-15 Camille Coron , Yves Le Jan

We consider a multi-type Moran model (in continuous time) with selection and type-dependent mutation. This paper is concerned with the evolution of genealogical information forward in time. For this purpose we define and analytically…

Probability · Mathematics 2015-11-19 Peter Seidel

Evolutionary models for populations of constant size are frequently studied using the Moran model, the Wright-Fisher model, or their diffusion limits. When evolution is neutral, a random genealogy given through Kingman's coalescent is used…

Populations and Evolution · Quantitative Biology 2012-07-31 Peter Pfaffelhuber , Benedikt Vogt

We study the evolution of the population genealogy in the classic neutral Moran Model of finite size and in discrete time. The stochastic transformations that shape a Moran population can be realized directly on its genealogy and give rise…

Populations and Evolution · Quantitative Biology 2019-02-08 Johannes Wirtz , Thomas Wiehe

$\Lambda$-Wright--Fisher processes provide a robust framework to describe the type-frequency evolution of an infinite neutral population. We add a polynomial drift to the corresponding stochastic differential equation to incorporate…

Probability · Mathematics 2023-04-26 Fernando Cordero , Sebastian Hummel , Emmanuel Schertzer

We consider the mutation--selection differential equation with pairwise interaction (or, equivalently, the diploid mutation--selection equation) and establish the corresponding ancestral process, which is a random tree and a variant of the…

Probability · Mathematics 2023-04-26 Ellen Baake , Fernando Cordero , Sebastian Hummel

The Moran process is a foundational model of genetic drift and mutation in finite populations. In its standard two-allele form with population size $n$, allele counts, and hence allele frequencies, change through stochastic replacement and…

Populations and Evolution · Quantitative Biology 2026-01-16 Dan Braha , Marcus A. M. de Aguiar

We interpret the Moran model of natural selection and drift as an algorithm for learning features of a simplified fitness landscape, specifically genotype superiority. This algorithm's efficiency in extracting these characteristics is…

Populations and Evolution · Quantitative Biology 2023-09-25 Miles Miller-Dickson , Christopher Rose , C. Brandon Ogbunugafor , I. Saira Mian

The Moran model with recombination is considered, which describes the evolution of the genetic composition of a population under recombination and resampling. There are $n$ sites (or loci), a finite number of letters (or alleles) at every…

Probability · Mathematics 2018-11-01 Mareike Esser , Sebastian Probst , Ellen Baake

In population genetics, extant samples are usually used for inference of past population genetic forces. With the Kingman coalescent and the backward diffusion equation, inference of the marginal likelihood proceeds from an extant sample…

Populations and Evolution · Quantitative Biology 2020-04-03 Claus Vogl , Sandra Peer

The Ancestral Selection Graph (ASG) is an important genealogical process which extends the well-known Kingman coalescent to incorporate natural selection. We show that the number of lineages of the ASG with and without mutation is…

Probability · Mathematics 2020-12-23 Philip A. Hanson , Paul A. Jenkins , Jere Koskela , Dario Spanò
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