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The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

In late 2019, a novel coronavirus, the SARS-CoV-2 outbreak was identified in Wuhan, China and later spread to every corner of the globe. Whilst the number of infection-induced deaths in Ghana, West Africa are minimal when compared with the…

Populations and Evolution · Quantitative Biology 2021-02-08 Edward Acheampong , Eric Okyere , Samuel Iddi , Joseph H. K. Bonney , Jonathan A. D. Wattis , Rachel L. Gomes

The outbreak of COVID-19 caused by SARS-CoV-2 has rapidly spread worldwide and has caused over 1,400,000 infections and 80,000 deaths. There are currently no drugs or vaccines with proven efficacy for its prevention and little knowledge was…

Genomics · Quantitative Biology 2020-04-13 Zhi Liu , Jianwei Wang , Yuyu Xu , Mengchen Guo , Kai Mi , Rui Xu , Yang Pei , Qiangkun Zhang , Xiaoting Luan , Zhibin Hu , Xingyin Liu#

The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global medical systems and economies, and rules our daily living life. Controlling the outbreak of SARS-CoV-2 has become one of the most important…

Medical Physics · Physics 2020-10-09 Jing Zhong , Enja Laureen Roesch , Thilo Viereck , Meinhard Schilling , Frank Ludwig

The emerging global infectious COVID-19 coronavirus disease by novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and the economy since it was identified in late December…

Genomics · Quantitative Biology 2020-03-25 Changchuan Yin

Infectious diseases are a significant threat to human society which was over sighted before the incidence of COVID-19, although according to the report of the World Health Organisation (WHO) about 4.2 million people die annually due to…

Physics and Society · Physics 2021-02-05 Md Shahzamal , Saeed Khan

During its first two years, the SARS-CoV-2 pandemic manifested as multiple waves shaped by complex interactions between variants of concern, non-pharmaceutical interventions, and the immunological landscape of the population. Understanding…

Physics and Society · Physics 2022-12-29 Otilia Boldea , Amir Alipoor , Sen Pei , Jeffrey Shaman , Ganna Rozhnova

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

Applications · Statistics 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

A molecular and cellular understanding of how SARS-CoV-2 variably infects and causes severe COVID-19 remains a bottleneck in developing interventions to end the pandemic. We sought to use deep learning to study the biology of SARS-CoV-2…

Machine Learning · Computer Science 2020-12-16 Arijit Sehanobish , Neal G. Ravindra , David van Dijk

The outbreak of corona virus disease 2019 (COVID-19), caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already created emergency situations in almost every country of the world. The disease spreads all…

Populations and Evolution · Quantitative Biology 2021-05-24 Abhishek Senapati , Sourav Rana , Tamalendu Das , Joydev Chattopadhyay

The rapid evolution and global impact of coronaviruses, notably SARS-CoV-1 and SARS-CoV-2, underscore the importance of understanding their molecular mechanisms in detail. This study focuses on the receptor-binding motif (RBM) within the…

Biological Physics · Physics 2026-03-16 Rafael B. Frigori

Tremendous effort has been given to the development of diagnostic tests, preventive vaccines, and therapeutic medicines for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much of…

Genomics · Quantitative Biology 2020-04-30 Rui Wang , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

Coronavirus disease (COVID-19) which is caused by SARS-COV2 has become a pandemic. This disease is highly infectious and potentially fatal, causing a global public health concern. To contain the spread of COVID-19, governments are adopting…

Physics and Society · Physics 2020-06-22 Sayantari Ghosh , Saumik Bhattacharya

The SARS-CoV-2 coronavirus, the etiologic agent responsible for COVID-19 coronavirus disease, is a global threat. To better understand viral tropism, we assessed the RNA expression of the coronavirus receptor, ACE2, as well as the viral S…

Cell Behavior · Quantitative Biology 2020-04-27 Waradon Sungnak , Ni Huang , Christophe Bécavin , Marijn Berg , HCA Lung Biological Network

Repeat asymptomatic testing in order to identify and quarantine infectious individuals has become a widely-used intervention to control SARS-CoV-2 transmission. In some workplaces, and in particular health and social care settings with…

Populations and Evolution · Quantitative Biology 2022-10-18 Carl A Whitfield , University of Manchester COVID-19 Modelling Group , Ian Hall

The drivers behind regional differences of SARS-CoV-2 spread on finer spatio-temporal scales are yet to be fully understood. Here we develop a data-driven modelling approach based on an age-structured compartmental model that compares 116…

A new coronavirus identified as SARS-CoV-2 virus has brought the world to a state of crisis, causing a major pandemic, claiming more than 433,000 lives and instigating major financial damage to the global economy. Despite current efforts,…

Biomolecules · Quantitative Biology 2020-06-18 Mohsen Chitsaz

More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies,…

The outbreak of COVID-19 caused by SARS-CoV-2 in Wuhan and other cities in China in 2019 has become a global pandemic as declared by World Health Organization (WHO) in the first quarter of 2020 . The delay in diagnosis, limited hospital…

Populations and Evolution · Quantitative Biology 2020-04-03 Stephen E. Moore , Eric Okyere

Increasing number in global COVID-19 cases demands for mathematical model to analyze the interaction between the virus dynamics and the response of innate and adaptive immunity. Here, based on the assumption of a weak and delayed response…

Populations and Evolution · Quantitative Biology 2021-01-13 Zhengqing Zhou , Zhiheng Zhao , Shuyu Shi , Jianghua Wu , Dianjie Li , Jianwei Li , Jingpeng Zhang , Ke Gui , Yu Zhang , Heng Mei , Yu Hu , Qi Ouyang , Fangting Li
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