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In the emerging era of big data, larger available clinical datasets and computational advances have sparked a massive interest in machine learning-based approaches. The number of manuscripts related to machine learning or artificial…

Machine Learning · Statistics 2020-06-29 Julius M. Kernbach , Victor E. Staartjes

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Unsupervised anomaly detection (AD) is critical for a wide range of practical applications, from network security to health and medical tools. Due to the diversity of problems, no single algorithm has been found to be superior for all AD…

Machine Learning · Computer Science 2023-05-18 Małgorzata Gutowska , Suzanne Little , Andrew McCarren

Scientific publications about machine learning in healthcare are often about implementing novel methods and boosting the performance - at least from a computer science perspective. However, beyond such often short-lived improvements, much…

Background: Psychedelic drugs facilitate profound changes in consciousness and have potential to provide insights into the nature of human mental processes and their relation to brain physiology. Yet published scientific literature reflects…

Quantitative Methods · Quantitative Biology 2012-06-05 Jeremy R. Coyle , David E. Presti , Matthew J. Baggott

Machine learning systems trained on electronic health records (EHRs) increasingly guide treatment decisions, but their reliability depends on the critical assumption that patients follow the prescribed treatments recorded in EHRs. Using EHR…

Machine Learning · Computer Science 2025-04-22 Zhongyuan Liang , Arvind Suresh , Irene Y. Chen

Clinical dataset labels are rarely certain as annotators disagree and confidence is not uniform across cases. Typical aggregation procedures, such as majority voting, obscure this variability. In simple experiments on medical imaging…

Informed selection of drug candidates for laboratory experimentation provides an efficient means of identifying suitable anti-cancer treatments. The advancement of artificial intelligence has led to the development of computational models…

We use multi-class machine learning classifiers to identify the stocks that outperform or underperform other stocks. The resulting long-short portfolios achieve annual Sharpe ratios of 1.67 (value-weighted) and 3.35 (equal-weighted), with…

General Finance · Quantitative Finance 2025-07-24 Yang Bai , Kuntara Pukthuanthong

We study the problem of detecting adverse drug events in electronic healthcare records. The challenge in this work is to aggregate heterogeneous data types involving diagnosis codes, drug codes, as well as lab measurements. An earlier…

Machine Learning · Computer Science 2019-07-16 Maria Bampa , Panagiotis Papapetrou

Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions…

Methodology · Statistics 2020-06-25 Simon Kocbek , Primoz Kocbek , Leona Cilar , Gregor Stiglic

In clinical practice, decision-making relies heavily on established protocols, often formalised as rules. Concurrently, Machine Learning (ML) models, trained on clinical data, aspire to integrate into medical decision-making processes.…

Artificial Intelligence · Computer Science 2024-11-06 Christel Sirocchi , Muhammad Suffian , Federico Sabbatini , Alessandro Bogliolo , Sara Montagna

We propose machine learning algorithms to automatically detect and predict clopidogrel treatment failure using longitudinal structured electronic health records (EHR). By drawing analogies between natural language and structured EHR, we…

Machine Learning · Computer Science 2023-10-16 Samuel Kim , In Gu Sean Lee , Mijeong Irene Ban , Jane Chiang

Bayesian Personalized Ranking (BPR), a collaborative filtering approach based on matrix factorization, frequently serves as a benchmark for recommender systems research. However, numerous studies often overlook the nuances of BPR…

Information Retrieval · Computer Science 2024-10-21 Aleksandr Milogradskii , Oleg Lashinin , Alexander P , Marina Ananyeva , Sergey Kolesnikov

Purpose: This study evaluates the effectiveness and impact of automated order-based protocol assignment for magnetic resonance imaging (MRI) exams using natural language processing (NLP) and deep learning (DL). Methods: NLP tools were…

Machine Learning · Computer Science 2021-06-17 Andrew S. Nencka , Mohammad Sherafati , Timothy Goebel , Parag Tolat , Kevin M. Koch

We study web and mobile applications that are used to schedule advance service, from medical appointments to restaurant reservations. We model them as online weighted bipartite matching problems with non-stationary arrivals. We propose new…

Optimization and Control · Mathematics 2018-05-29 Xinshang Wang , Van-Anh Truong , David Bank

We discovered secular trend bias in a drug effectiveness study for a recently approved drug. We compared treatment outcomes between patients who received the newly approved drug and patients exposed to the standard treatment. All patients…

Machine Learning · Computer Science 2018-08-21 Sharon Hensley Alford , Piyush Madan , Shilpa Mahatma , Italo Buleje , Yanyan Han , Fang Lu

This thesis explores a number of online machine learning algorithms. From a theoret- ical perspective, it assesses their employability for a particular function approximation problem where the analytical models fall short. Furthermore, it…

Machine Learning · Computer Science 2016-05-04 Ahmet Anil Pala

A myriad of measures to illustrate performance of predictive artificial intelligence (AI) models have been proposed in the literature. Selecting appropriate performance measures is essential for predictive AI models that are developed to be…

The rapid advancement of large language models (LLMs) has accelerated their integration into clinical decision support, particularly in prescription review. To enable systematic and fine-grained evaluation, we developed RxBench, a…

Computation and Language · Computer Science 2025-12-03 Yan Yang , Mouxiao Bian , Peiling Li , Bingjian Wen , Ruiyao Chen , Kangkun Mao , Xiaojun Ye , Tianbin Li , Pengcheng Chen , Bing Han , Jie Xu , Kaifeng Qiu , Junyan Wu