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Clinical trials usually target average treatment effects, but treatment decisions are made for individuals. This tension motivates a common criticism of evidence-based medicine: a treatment that is beneficial on average may be inappropriate…

Applications · Statistics 2026-05-29 Zach Shahn , Mats Stensrud

Personalizing drug prescriptions in cancer care based on genomic information requires associating genomic markers with treatment effects. This is an unsolved challenge requiring genomic patient data in yet unavailable volumes as well as…

Machine unlearning (MU) aims to remove the influence of certain data points from a trained model without costly retraining. Most practical MU algorithms are only approximate and their performance can only be assessed empirically. Care must…

Machine Learning · Computer Science 2026-01-01 Jamie Lanyon , Axel Finke , Petros Andreou , Georgina Cosma

The accuracy of machine learning systems is a widely studied research topic. Established techniques such as cross-validation predict the accuracy on unseen data of the classifier produced by applying a given learning method to a given…

Machine Learning · Computer Science 2012-12-06 J. E. Smith , P. Caleb-Solly , M. A. Tahir , D. Sannen , H. van-Brussel

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

Machine Learning · Statistics 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

One of the promising methods for the treatment of complex diseases such as cancer is combinational therapy. Due to the combinatorial complexity, machine learning models can be useful in this field, where significant improvements have…

Machine Learning · Computer Science 2020-01-08 Işıksu Ekşioğlu , Mehmet Tan

The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models…

Purpose: Summarize ICU delirium prediction models published within the past five years. Methods: Electronic searches were conducted in April 2019 using PubMed, Embase, Cochrane Central, Web of Science, and CINAHL to identify peer reviewed…

In the pharmaceutical industry, the use of artificial intelligence (AI) has seen consistent growth over the past decade. This rise is attributed to major advancements in statistical machine learning methodologies, computational capabilities…

Methodology · Statistics 2023-12-01 Yuhan Li , Hongtao Zhang , Keaven Anderson , Songzi Li , Ruoqing Zhu

In many practical tasks it is needed to estimate an effect of treatment on individual level. For example, in medicine it is essential to determine the patients that would benefit from a certain medicament. In marketing, knowing the persons…

Methodology · Statistics 2019-02-28 Aleksey Buzmakov

A growing body of work uses the paradigm of algorithmic fairness to frame the development of techniques to anticipate and proactively mitigate the introduction or exacerbation of health inequities that may follow from the use of…

Machine Learning · Statistics 2022-02-07 Stephen R. Pfohl , Yizhe Xu , Agata Foryciarz , Nikolaos Ignatiadis , Julian Genkins , Nigam H. Shah

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

This transformation of food delivery businesses to online platforms has gained high attention in recent years. This due to the availability of customizing ordering experiences, easy payment methods, fast delivery, and others. The…

Machine Learning · Statistics 2021-10-04 Batool Madani , Hussam Alshraideh

As machine learning (ML) models, trained on real-world datasets, become common practice, it is critical to measure and quantify their potential biases. In this paper, we focus on renal failure and compare a commonly used traditional risk…

Machine Learning · Computer Science 2019-11-19 Josie Williams , Narges Razavian

Background: Clinical prediction models for a health condition are commonly evaluated regarding performance for a population, although decisions are made for individuals. The classic view relates uncertainty in risk estimates for individuals…

Practitioners in medicine, business, political science, and other fields are increasingly aware that decisions should be personalized to each patient, customer, or voter. A given treatment (e.g. a drug or advertisement) should be…

Machine Learning · Statistics 2018-06-15 Alejandro Schuler , Michael Baiocchi , Robert Tibshirani , Nigam Shah

In this paper, we study a novel problem: "automatic prescription recommendation for PD patients." To realize this goal, we first build a dataset by collecting 1) symptoms of PD patients, and 2) their prescription drug provided by…

Machine Learning · Computer Science 2020-08-03 Yinghuan Shi , Wanqi Yang , Kim-Han Thung , Hao Wang , Yang Gao , Yang Pan , Li Zhang , Dinggang Shen

In machine learning, we traditionally evaluate the performance of a single model, averaged over a collection of test inputs. In this work, we propose a new approach: we measure the performance of a collection of models when evaluated on a…

Machine Learning · Computer Science 2022-06-08 Gal Kaplun , Nikhil Ghosh , Saurabh Garg , Boaz Barak , Preetum Nakkiran

Fairness and bias are crucial concepts in artificial intelligence, yet they are relatively ignored in machine learning applications in clinical psychiatry. We computed fairness metrics and present bias mitigation strategies using a model…

Machine Learning · Computer Science 2022-05-25 Pablo Mosteiro , Jesse Kuiper , Judith Masthoff , Floortje Scheepers , Marco Spruit

Mining social media messages such as tweets, articles, and Facebook posts for health and drug related information has received significant interest in pharmacovigilance research. Social media sites (e.g., Twitter), have been used for…

Computation and Language · Computer Science 2018-08-08 Debanjan Mahata , Jasper Friedrichs , Rajiv Ratn Shah , Jing Jiang
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