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Machine-learned diagnosis models have shown promise as medical aides but are trained under a closed-set assumption, i.e. that models will only encounter conditions on which they have been trained. However, it is practically infeasible to…

Machine Learning · Computer Science 2019-10-08 Viraj Prabhu , Anitha Kannan , Geoffrey J. Tso , Namit Katariya , Manish Chablani , David Sontag , Xavier Amatriain

INTRODUCTION: The pharmacological treatment of Major Depressive Disorder (MDD) relies on a trial-and-error approach. We introduce an artificial intelligence (AI) model aiming to personalize treatment and improve outcomes, which was deployed…

Electronic health records are an increasingly important resource for understanding the interactions between patient health, environment, and clinical decisions. In this paper we report an empirical study of predictive modeling of several…

Computers and Society · Computer Science 2019-03-29 William La Cava , Christopher Bauer , Jason H. Moore , Sarah A Pendergrass

Opioid use disorder (OUD) continuously poses major public health challenges and social implications worldwide with dramatic rise of opioid dependence leading to potential abuse. Despite that a few pharmacological agents have been approved…

Biomolecules · Quantitative Biology 2023-01-13 Hongsong Feng , Rana Elladki , Jian Jiang , Guo-Wei Wei

Clinical trials are conducted to test the effectiveness and safety of potential drugs in humans for regulatory approval. Machine learning (ML) has recently emerged as a new tool to assist in clinical trials. Despite this progress, there…

Artificial Intelligence · Computer Science 2023-10-06 Zifeng Wang , Brandon Theodorou , Tianfan Fu , Cao Xiao , Jimeng Sun

In many medical and business applications, researchers are interested in estimating individualized treatment effects using data from a randomized experiment. For example in medical applications, doctors learn the treatment effects from…

Methodology · Statistics 2022-03-01 Kevin Wu Han , Han Wu

In recent years, machine learning has been proposed as a promising strategy to build accurate scoring functions for computational docking finalized to numerically empowered drug discovery. However, the latest studies have suggested that…

Quantitative Methods · Quantitative Biology 2023-02-17 F. Pellicani , D. Dal Ben , A. Perali , S. Pilati

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

Estimating average human performance has been performed inconsistently in research in diagnostic medicine. This has been particularly apparent in the field of medical artificial intelligence, where humans are often compared against AI…

Methodology · Statistics 2020-09-28 Luke Oakden-Rayner , Lyle Palmer

Recommender systems present a customized list of items based upon user or item characteristics with the objective of reducing a large number of possible choices to a smaller ranked set most likely to appeal to the user. A variety of…

Information Retrieval · Computer Science 2024-07-02 William Noffsinger

Checklists are simple decision aids that are often used to promote safety and reliability in clinical applications. In this paper, we present a method to learn checklists for clinical decision support. We represent predictive checklists as…

Machine Learning · Computer Science 2022-01-19 Haoran Zhang , Quaid Morris , Berk Ustun , Marzyeh Ghassemi

Human decision-making differs due to variation in both incentives and available information. This constitutes a substantial challenge for the evaluation of whether and how machine learning predictions can improve decision outcomes. We…

General Economics · Economics 2020-11-24 Michael Allan Ribers , Hannes Ullrich

Predictions and forecasts of machine learning models should take the form of probability distributions, aiming to increase the quantity of information communicated to end users. Although applications of probabilistic prediction and…

Machine Learning · Statistics 2024-03-19 Hristos Tyralis , Georgia Papacharalampous

To enable personalized cancer treatment, machine learning models have been developed to predict drug response as a function of tumor and drug features. However, most algorithm development efforts have relied on cross validation within a…

Rheumatoid arthritis (RA) is an autoimmune condition caused when patients' immune system mistakenly targets their own tissue. Machine learning (ML) has the potential to identify patterns in patient electronic health records (EHR) to…

Quantitative Methods · Quantitative Biology 2022-10-25 Shengjia Chen , Nikunj Gupta , Woodward B. Galbraith , Valay Shah , Jacopo Cirrone

Millions of unsolicited medical inquiries are received by pharmaceutical companies every year. It has been hypothesized that these inquiries represent a treasure trove of information, potentially giving insight into matters regarding…

While machine learning (ML) methods have received a lot of attention in recent years, these methods are primarily for prediction. Empirical researchers conducting policy evaluations are, on the other hand, pre-occupied with causal problems,…

Machine Learning · Statistics 2019-03-04 Noemi Kreif , Karla DiazOrdaz

Since coronavirus has shown up, inaccessibility of legitimate clinical resources is at its peak, like the shortage of specialists, healthcare workers, lack of proper equipment and medicines. The entire medical fraternity is in distress,…

Information Retrieval · Computer Science 2021-04-06 Satvik Garg

Dental provider classification plays a crucial role in optimizing healthcare resource allocation and policy planning. Effective categorization of providers, such as standard rendering providers and safety net clinic (SNC) providers,…

Machine Learning · Computer Science 2025-06-06 Mohammad Subhi Al-Batah , Muhyeeddin Alqaraleh , Mowafaq Salem Alzboon , Abdullah Alourani

Artificial intelligence may assist healthcare systems in meeting increasing demand for pathology services while maintaining diagnostic quality and reducing turnaround time and costs. We aimed to investigate the performance of an…