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Recently, the Network Representation Learning (NRL) techniques, which represent graph structure via low-dimension vectors to support social-oriented application, have attracted wide attention. Though large efforts have been made, they may…
Large-scale multi-relational embedding refers to the task of learning the latent representations for entities and relations in large knowledge graphs. An effective and scalable solution for this problem is crucial for the true success of…
Multivalued treatment models have typically been studied under restrictive assumptions: ordered choice, and more recently unordered monotonicity. We show how treatment effects can be identified in a more general class of models that allows…
In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…
A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be…
Multilayer networks offer a powerful framework for modeling complex systems across diverse domains, effectively capturing multiple types of connections and interdependent subsystems commonly found in real world scenarios. To analyze these…
Causal inference methods are widely applied in the fields of medicine, policy, and economics. Central to these applications is the estimation of treatment effects to make decisions. Current methods make binary yes-or-no decisions based on…
Key features of mental illnesses are reflected in speech. Our research focuses on designing a multimodal deep learning structure that automatically extracts salient features from recorded speech samples for predicting various mental…
Neurological disorders represent a growing global health burden requiring long-term, interdisciplinary rehabilitation. Computational neurorehabilitation (compNR) - the use of data-driven and model-based approaches to personalize treatment -…
Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…
We propose a new modeling and estimation approach to select the optimal treatment regime from different options through constructing a robust estimating equation. The method is protected against misspecification of the propensity score…
Training a single network with multiple objectives often leads to conflicting gradients that degrade shared representations, forcing them into a compromised state that is suboptimal for any single task--a problem we term latent…
Conventional treatment policies map patient covariates to a single recommended intervention in order to maximize expected clinical outcomes. Although a rich body of causal inference methods has been developed to estimate such policies,…
Machine learning methods for estimating heterogeneous treatment effects (HTE) facilitate large-scale personalized decision-making across various domains such as healthcare, policy making, education, and more. Current machine learning…
Deep neural networks come in many sizes and architectures. The choice of architecture, in conjunction with the dataset and learning algorithm, is commonly understood to affect the learned neural representations. Yet, recent results have…
Differential diagnosis of mental disorders remains a fundamental challenge in real-world clinical practice, where multiple conditions often exhibit overlapping symptoms. However, most existing public datasets are developed under…
In open data sets of functional magnetic resonance imaging (fMRI), the heterogeneity of the data is typically attributed to a combination of factors, including differences in scanning procedures, the presence of confounding effects, and…
Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…
In recent years, representation learning has become the research focus of the machine learning community. Large-scale neural networks are a crucial step toward achieving general intelligence, with their success largely attributed to their…
Data imbalance between common and rare diseases during model training often causes intelligent diagnosis systems to have biased predictions towards common diseases. The state-of-the-art approaches apply a two-stage learning framework to…