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As the aging population grows, particularly for the baby boomer generation, the United States is witnessing a significant increase in the elderly population experiencing multifunctional disabilities. These disabilities, stemming from a…

Machine Learning · Computer Science 2024-04-09 Suiyao Chen , Xinyi Liu , Yulei Li , Jing Wu , Handong Yao

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

With the advancement in drug development, multiple treatments are available for a single disease. Patients can often benefit from taking multiple treatments simultaneously. For example, patients in Clinical Practice Research Datalink (CPRD)…

Applications · Statistics 2018-04-17 Muxuan Liang , Ye Ting , Haoda Fu

Perceptual learning enables humans to recognize and represent stimuli invariant to various transformations and build a consistent representation of the self and physical world. Such representations preserve the invariant physical relations…

Neural and Evolutionary Computing · Computer Science 2020-07-02 Du Xiaorui , Yavuzhan Erdem , Immanuel Schweizer , Cristian Axenie

We investigate how to exploit structural similarities of an individual's potential outcomes (POs) under different treatments to obtain better estimates of conditional average treatment effects in finite samples. Especially when it is…

Machine Learning · Statistics 2021-10-26 Alicia Curth , Mihaela van der Schaar

Cell heterogeneity plays an important role in patient responses to drug treatments. In many cancers, it is associated with poor treatment outcomes. Many modern drug combination therapies aim to exploit cell heterogeneity, but determining…

Quantitative Methods · Quantitative Biology 2025-02-18 Simon F. Martina-Perez , Samuel W. S. Johnson , Rebecca M. Crossley , Jennifer C. Kasemeier , Paul M. Kulesa , Ruth E. Baker

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

Hypergraph can capture complex and higher-order dependencies among learners and learning resources in personalized educational recommender systems. Many existing hypergraph-based recommendation approaches underexplored the dynamic…

Information Retrieval · Computer Science 2026-03-17 Tao Xie , Yan Li , Yongpan Sheng , Jian Liao

In medical image processing, accurate diagnosis is of paramount importance. Leveraging machine learning techniques, particularly top-rank learning, shows significant promise by focusing on the most crucial instances. However, challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Xiaotong Ji , Ryoma Bise , Seiichi Uchida

Multistate models offer a powerful framework for studying disease processes and can be used to formulate intensity-based and more descriptive marginal regression models. They also represent a natural foundation for the construction of joint…

Effective modeling of heterogeneous subpopulations presents a significant challenge due to variations in individual characteristics and behaviors. This paper proposes a novel approach to address this issue through multi-task learning (MTL)…

Machine Learning · Computer Science 2025-08-22 Elif Konyar , Mostafa Reisi Gahrooei , Kamran Paynabar

Medical treatments tailored to a patient's baseline characteristics hold the potential of improving patient outcomes while reducing negative side effects. Learning individualized treatment rules (ITRs) often requires aggregation of multiple…

Machine Learning · Statistics 2022-12-15 Jay Jojo Cheng , Jared D. Huling , Guanhua Chen

Evaluating the causal impacts of possible interventions is crucial for informing decision-making, especially towards improving access to opportunity. However, if causal effects are heterogeneous and predictable from covariates, personalized…

Machine Learning · Computer Science 2024-04-30 Ezinne Nwankwo , Michael I. Jordan , Angela Zhou

Recent advances in deep learning have led to the development of models approaching the human level of accuracy. However, healthcare remains an area lacking in widespread adoption. The safety-critical nature of healthcare results in a…

Signal Processing · Electrical Eng. & Systems 2023-02-07 Irfan Al-Hussaini , Cassie S. Mitchell

This work proposes Multi-task Meta Learning (MTML), integrating two learning paradigms Multi-Task Learning (MTL) and meta learning, to bring together the best of both worlds. In particular, it focuses simultaneous learning of multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Richa Upadhyay , Prakash Chandra Chhipa , Ronald Phlypo , Rajkumar Saini , Marcus Liwicki

We consider the general class of time-homogeneous stochastic dynamical systems, both discrete and continuous, and study the problem of learning a representation of the state that faithfully captures its dynamics. This is instrumental to…

Machine Learning · Computer Science 2024-03-15 Vladimir R. Kostic , Pietro Novelli , Riccardo Grazzi , Karim Lounici , Massimiliano Pontil

Due to the complexity of the human body, most diseases present a high inter-personal variability in the way they manifest, i.e. in their phenotype, which has important clinical repercussions - as for instance the difficulty in defining…

Physics and Society · Physics 2018-06-06 Massimiliano Zanin , Juan Manuel Tuñas , Ernestina Menasalvas

Clinical decision support tools rooted in machine learning and optimization can provide significant value to healthcare providers, including through better management of intensive care units. In particular, it is important that the patient…

Machine Learning · Computer Science 2021-12-20 Fernando Lejarza , Jacob Calvert , Misty M Attwood , Daniel Evans , Qingqing Mao

Practical Imitation Learning (IL) systems rely on large human demonstration datasets for successful policy learning. However, challenges lie in maintaining the quality of collected data and addressing the suboptimal nature of some…

Robotics · Computer Science 2025-05-07 Sachit Kuhar , Shuo Cheng , Shivang Chopra , Matthew Bronars , Danfei Xu

Network embedding is an effective technique to learn the low-dimensional representations of nodes in networks. Real-world networks are usually with multiplex or having multi-view representations from different relations. Recently, there has…

Machine Learning · Computer Science 2022-03-08 Qifan Wang , Yi Fang , Anirudh Ravula , Ruining He , Bin Shen , Jingang Wang , Xiaojun Quan , Dongfang Liu
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