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Current knowledge graph (KG) construction methods are confirmatory, focusing on recovering known relationships rather than identifying novel or context-dependent nodes. This paper proposes a phenotype-driven and evidence-governed framework…

Artificial Intelligence · Computer Science 2026-04-21 Adela Bâra , Simona-Vasilica Oprea

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Graph representation learning methods are highly effective in handling complex non-Euclidean data by capturing intricate relationships and features within graph structures. However, traditional methods face challenges when dealing with…

Machine Learning · Computer Science 2025-02-25 Hang Gao , Chenhao Zhang , Fengge Wu , Junsuo Zhao , Changwen Zheng , Huaping Liu

Knowledge graphs are structured representations of facts in a graph, where nodes represent entities and edges represent relationships between them. Recent research has resulted in the development of several large KGs. However, all of them…

Computation and Language · Computer Science 2020-04-17 Shikhar Vashishth

Accurate identification of disease genes has consistently been one of the keys to decoding a disease's molecular mechanism. Most current approaches focus on constructing biological networks and utilizing machine learning, especially, deep…

Artificial Intelligence · Computer Science 2023-03-17 Xinyan Wang , Ting Jia , Chongyu Wang , Kuan Xu , Zixin Shu , Jian Yu , Kuo Yang , Xuezhong Zhou

Personalized diagnoses have not been possible due to sear amount of data pathologists have to bear during the day-to-day routine. This lead to the current generalized standards that are being continuously updated as new findings are…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Jialun Wu , Zeyu Gao , Haichuan Zhang , Ruonan Zhang , Tieliang Gong , Chunbao Wang , Chen Li

A large-scale knowledge graph enhances reproducibility in biomedical data discovery by providing a standardized, integrated framework that ensures consistent interpretation across diverse datasets. It improves generalizability by connecting…

Methodology · Statistics 2024-10-11 Suqi Liu , Tianxi Cai , Xiaoou Li

In the context of personalized medicine, text mining methods pose an interesting option for identifying disease-gene associations, as they can be used to generate novel links between diseases and genes which may complement knowledge from…

Computation and Language · Computer Science 2017-09-28 Hendrik ter Horst , Matthias Hartung , Roman Klinger , Matthias Zwick , Philipp Cimiano

A dynamic graph (DG) is frequently encountered in numerous real-world scenarios. Consequently, A dynamic graph convolutional network (DGCN) has been successfully applied to perform precise representation learning on a DG. However,…

Machine Learning · Computer Science 2025-04-23 Minglian Han

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose…

Computation and Language · Computer Science 2025-02-18 Alexandru Lecu , Adrian Groza , Lezan Hawizy

This paper proposes a large language model (LLM) approach that integrates graph-structured information for knowledge reasoning in tobacco pest and disease control. Built upon the GraphRAG framework, the proposed method enhances knowledge…

Computation and Language · Computer Science 2025-12-29 Siyu Li , Chenwei Song , Wan Zhou , Xinyi Liu

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Most existing re-identification methods focus on learning robust and discriminative features with deep convolution networks. However, many of them consider content similarity separately and fail to utilize the context information of the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Deyi Ji , Haoran Wang , Hanzhe Hu , Weihao Gan , Wei Wu , Junjie Yan

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Understanding disease-gene associations is essential for unravelling disease mechanisms and advancing diagnostics and therapeutics. Traditional approaches based on manual curation and literature review are labour-intensive and not scalable,…

Machine Learning · Computer Science 2026-02-24 Osman Onur Kuzucu , Tunca Doğan

Emotions are an inherent part of human interactions, and consequently, it is imperative to develop AI systems that understand and recognize human emotions. During a conversation involving various people, a person's emotions are influenced…

Computation and Language · Computer Science 2022-05-06 Abhinav Joshi , Ashwani Bhat , Ayush Jain , Atin Vikram Singh , Ashutosh Modi

As the healthcare sector is facing major challenges, such as aging populations, staff shortages, and common chronic diseases, delivering high-quality care to individuals has become very difficult. Conversational agents have shown to be a…

Computation and Language · Computer Science 2023-03-28 Phillip Schneider , Nils Rehtanz , Kristiina Jokinen , Florian Matthes

Constructing responses in task-oriented dialogue systems typically relies on information sources such the current dialogue state or external databases. This paper presents a novel approach to knowledge-grounded response generation that…

Computation and Language · Computer Science 2023-10-23 Nicholas Thomas Walker , Stefan Ultes , Pierre Lison

Knowledge graphs are often used to represent structured information in a flexible and efficient manner, but their use in situated dialogue remains under-explored. This paper presents a novel conversational model for human--robot interaction…

Robotics · Computer Science 2025-04-02 Nicholas Thomas Walker , Stefan Ultes , Pierre Lison

Biomedical knowledge graphs (KG) are heterogenous networks consisting of biological entities as nodes and relations between them as edges. These entities and relations are extracted from millions of research papers and unified in a single…

Artificial Intelligence · Computer Science 2022-11-11 Dattaraj J. Rao , Shraddha S. Mane , Mukta A. Paliwal