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The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing…

Biological Physics · Physics 2015-05-14 Cesar A. Hidalgo , Nicholas Blumm , Albert-Laszlo Barabasi , Nicholas Christakis

This work considers the problem of heterogeneous graph-level anomaly detection. Heterogeneous graphs are commonly used to represent behaviours between different types of entities in complex industrial systems for capturing as much…

Machine Learning · Computer Science 2023-08-29 Jiaxi Li , Guansong Pang , Ling Chen , Mohammad-Reza Namazi-Rad

Healthcare professionals need effective ways to use, understand, and validate AI-driven clinical decision support systems. Existing systems face two key limitations: complex visualizations and a lack of grounding in scientific evidence. We…

Human-Computer Interaction · Computer Science 2025-07-08 Reza Samimi , Aditya Bhattacharya , Lucija Gosak , Gregor Stiglic , Katrien Verbert

Ontology-based approaches for predicting gene-disease associations include the more classical semantic similarity methods and more recently knowledge graph embeddings. While semantic similarity is typically restricted to hierarchical…

Machine Learning · Computer Science 2021-06-01 Susana Nunes , Rita T. Sousa , Catia Pesquita

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this…

With the advances of data-driven machine learning research, a wide variety of prediction problems have been tackled. It has become critical to explore how machine learning and specifically deep learning methods can be exploited to analyse…

Machine Learning · Computer Science 2021-11-09 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

This paper addresses the problems of missing reasoning chains and insufficient entity-level semantic understanding in large language models when dealing with tasks that require structured knowledge. It proposes a fine-tuning algorithm…

Computation and Language · Computer Science 2025-08-21 Wuyang Zhang , Yexin Tian , Xiandong Meng , Mengjie Wang , Junliang Du

Medical dialogue systems have attracted growing research attention as they have the potential to provide rapid diagnoses, treatment plans, and health consultations. In medical dialogues, a proper diagnosis is crucial as it establishes the…

Computation and Language · Computer Science 2024-01-15 Kaishuai Xu , Wenjun Hou , Yi Cheng , Jian Wang , Wenjie Li

Knowledge graph (KG) embedding has been used to benefit the diagnosis of animal diseases by analyzing electronic medical records (EMRs), such as notes and veterinary records. However, learning representations to capture entities and…

Artificial Intelligence · Computer Science 2023-09-08 Van Thuy Hoang , Sang Thanh Nguyen , Sangmyeong Lee , Jooho Lee , Luong Vuong Nguyen , O-Joun Lee

Adverse drug events (ADEs) are an important aspect of drug safety. Various texts such as biomedical literature, drug reviews, and user posts on social media and medical forums contain a wealth of information about ADEs. Recent studies have…

Computation and Language · Computer Science 2024-05-21 Shaoxiong Ji , Ya Gao , Pekka Marttinen

Generating knowledge grounded responses in both goal and non-goal oriented dialogue systems is an important research challenge. Knowledge Graphs (KG) can be viewed as an abstraction of the real world, which can potentially facilitate a…

Computation and Language · Computer Science 2021-03-31 Debanjan Chaudhuri , Md Rashad Al Hasan Rony , Jens Lehmann

Drug-target interaction (DTI) prediction is a core task in drug development and precision medicine in the biomedical field. However, traditional machine learning methods generally have the black box problem, which makes it difficult to…

Quantitative Methods · Quantitative Biology 2025-04-30 Wenfeng Dai , Yanhong Wang , Shuai Yan , Qingzhi Yu , Xiang Cheng

Medication recommendation is a crucial task for intelligent healthcare systems. Previous studies mainly recommend medications with electronic health records (EHRs). However, some details of interactions between doctors and patients may be…

Computation and Language · Computer Science 2022-09-16 Zhenfeng He , Yuqiang Han , Zhenqiu Ouyang , Wei Gao , Hongxu Chen , Guandong Xu , Jian Wu

Medical question answer (QA) assistants respond to lay users' health-related queries by synthesizing information from multiple sources using natural language processing and related techniques. They can serve as vital tools to alleviate…

Computation and Language · Computer Science 2024-10-01 Prakash Chandra Sukhwal , Vaibhav Rajan , Atreyi Kankanhalli

Knowledge-grounded dialogue systems are intended to convey information that is based on evidence provided in a given source text. We discuss the challenges of training a generative neural dialogue model for such systems that is controlled…

Computation and Language · Computer Science 2021-07-16 Hannah Rashkin , David Reitter , Gaurav Singh Tomar , Dipanjan Das

Answering complex questions about textual narratives requires reasoning over both stated context and the world knowledge that underlies it. However, pretrained language models (LM), the foundation of most modern QA systems, do not robustly…

Computation and Language · Computer Science 2022-01-25 Xikun Zhang , Antoine Bosselut , Michihiro Yasunaga , Hongyu Ren , Percy Liang , Christopher D. Manning , Jure Leskovec

We propose a deep graph approach to address the task of speech emotion recognition. A compact, efficient and scalable way to represent data is in the form of graphs. Following the theory of graph signal processing, we propose to model…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 A. Shirian , T. Guha

Multi-scale biomedical knowledge networks are expanding with emerging experimental technologies that generates multi-scale biomedical big data. Link prediction is increasingly used especially in bipartite biomedical networks to identify…

Social and Information Networks · Computer Science 2022-02-25 Jinjiang Guo , Jie Li , Dawei Leng , Lurong Pan

Language models have achieved impressive performances on dialogue generation tasks. However, when generating responses for a conversation that requires factual knowledge, they are far from perfect, due to an absence of mechanisms to…

Computation and Language · Computer Science 2023-05-31 Minki Kang , Jin Myung Kwak , Jinheon Baek , Sung Ju Hwang
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