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In this paper, we review recent results of ours concerning branching processes with general lifetimes and neutral mutations, under the infinitely many alleles model, where mutations can occur either at birth of individuals or at a constant…

Probability · Mathematics 2012-11-29 Nicolas Champagnat , Amaury Lambert , Mathieu Richard

The Moran process is a foundational model of genetic drift and mutation in finite populations. In its standard two-allele form with population size $n$, allele counts, and hence allele frequencies, change through stochastic replacement and…

Populations and Evolution · Quantitative Biology 2026-01-16 Dan Braha , Marcus A. M. de Aguiar

We provide a nonasymptotic analysis of convergence to stationarity for a collection of Markov chains on multivariate state spaces, from arbitrary starting points, thereby generalizing results in [Khare and Zhou Ann. Appl. Probab. 19 (2009)…

Probability · Mathematics 2013-02-25 Kshitij Khare , Nabanita Mukherjee

In genetics the Moran model describes the neutral evolution of a bi-allelic gene in a population of haploid individuals subjected to mutations. We show in this paper that this model can be mapped into an influence dynamical process on…

Populations and Evolution · Quantitative Biology 2015-03-17 Marcus A. M. de Aguiar , Yaneer Bar-Yam

The goal of this article is to study the limit of the empirical distribution induced by a mutation-selection multi-allelic Moran model, whose dynamic is given by a continuous-time irreducible Markov chain. The rate matrix driving the…

Probability · Mathematics 2022-09-28 Bertrand Cloez , Josué Corujo

We consider a population model where individuals behave independently from each other and whose genealogy is described by a chronological tree called splitting tree. The individuals have i.i.d. (non-exponential) lifetime durations and give…

Probability · Mathematics 2014-05-20 Mathieu Richard

The mother-dependent neutral mutations model describes the evolution of a population across discrete generations, where neutral mutations occur among a finite set of possible alleles. In this model, each mutant child acquires a type…

Probability · Mathematics 2025-04-29 Airam Blancas , Maria Clara Fittipaldi , Sarai Hernandez-Torres

We provide a sharp nonasymptotic analysis of the rates of convergence for some standard multivariate Markov chains using spectral techniques. All chains under consideration have multivariate orthogonal polynomial as eigenfunctions. Our…

Probability · Mathematics 2009-06-24 Kshitij Khare , Hua Zhou

In this article, a biallelic reversible mutation model with linear and quadratic selection is analyzed. The approach reconnects to one proposed by Kimura ( Possibility of extensive neutral evolution under stabilizing selection with special…

Populations and Evolution · Quantitative Biology 2021-03-30 Claus Vogl , Lynette Caitlin Mikula

This paper gives a new flavor of what Peter Jagers and his co-authors call `the path to extinction'. In a neutral population with constant size $N$, we assume that each individual at time $0$ carries a distinct type, or allele. We consider…

Probability · Mathematics 2026-01-14 Guillaume Achaz , Amaury Lambert , Emmanuel Schertzer

We introduce a continuous-time Markov chain describing dynamic allelic partitions which extends the branching process construction of the Pitman sampling formula in Pitman (2006) and the birth-and-death process with immigration studied in…

Probability · Mathematics 2020-03-17 Matteo Giordano , Pierpaolo De Blasi , Matteo Ruggiero

We consider two versions of stochastic population models with mutation and selection. The first approach relies on a multitype branching process; here, individuals reproduce and change type (i.e., mutate) independently of each other,…

Populations and Evolution · Quantitative Biology 2009-02-19 E. Baake , R. Bialowons

We study the evolution of the population genealogy in the classic neutral Moran Model of finite size and in discrete time. The stochastic transformations that shape a Moran population can be realized directly on its genealogy and give rise…

Populations and Evolution · Quantitative Biology 2019-02-08 Johannes Wirtz , Thomas Wiehe

We consider a multi-type Moran model (in continuous time) with selection and type-dependent mutation. This paper is concerned with the evolution of genealogical information forward in time. For this purpose we define and analytically…

Probability · Mathematics 2015-11-19 Peter Seidel

We introduce a unified operator-theoretic framework for analyzing mixing times of finite-state ergodic Markov chains that applies to both reversible and non-reversible dynamics. The central object in our analysis is the projected transition…

Probability · Mathematics 2025-11-05 Muhammad Abdullah Naeem

We consider a Moran model with two allelic types, mutation and selection. In this work, we study the behaviour of the proportion of fit individuals when the size of the population tends to infinity, without any rescaling of parameters or…

Probability · Mathematics 2018-04-05 Fernando Cordero

We construct an individual-based metapopulation model of population genetics featuring migration, mutation, selection and genetic drift. In the case of a single `island', the model reduces to the Moran model. Using the diffusion…

Populations and Evolution · Quantitative Biology 2015-04-16 George W. A. Constable , Alan J. McKane

We study a general setting of neutral evolution in which the population is of finite, constant size and can have spatial structure. Mutation leads to different genetic types ("traits"), which can be discrete or continuous. Under minimal…

Populations and Evolution · Quantitative Biology 2018-11-02 Alex McAvoy , Ben Adlam , Benjamin Allen , Martin A. Nowak

We study the fixation probability for two versions of the Moran process on the random graph $G_{n,p}$ at the threshold for connectivity. The Moran process models the spread of a mutant population in a network. Throughtout the process there…

Probability · Mathematics 2025-02-17 Alan Frieze , Wesley Pegden

We consider a general class of discrete, two-dimensional Markov chains modeling the dynamics of a population with two types, without mutation or immigration, and neutral in the sense that type has no influence on each individual's birth or…

Probability · Mathematics 2012-02-22 Nicolas Champagnat , Persi Diaconis , Laurent Miclo
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