Related papers: On the spectrum and ergodicity of a neutral multi-…
In this paper, we review recent results of ours concerning branching processes with general lifetimes and neutral mutations, under the infinitely many alleles model, where mutations can occur either at birth of individuals or at a constant…
The Moran process is a foundational model of genetic drift and mutation in finite populations. In its standard two-allele form with population size $n$, allele counts, and hence allele frequencies, change through stochastic replacement and…
We provide a nonasymptotic analysis of convergence to stationarity for a collection of Markov chains on multivariate state spaces, from arbitrary starting points, thereby generalizing results in [Khare and Zhou Ann. Appl. Probab. 19 (2009)…
In genetics the Moran model describes the neutral evolution of a bi-allelic gene in a population of haploid individuals subjected to mutations. We show in this paper that this model can be mapped into an influence dynamical process on…
The goal of this article is to study the limit of the empirical distribution induced by a mutation-selection multi-allelic Moran model, whose dynamic is given by a continuous-time irreducible Markov chain. The rate matrix driving the…
We consider a population model where individuals behave independently from each other and whose genealogy is described by a chronological tree called splitting tree. The individuals have i.i.d. (non-exponential) lifetime durations and give…
The mother-dependent neutral mutations model describes the evolution of a population across discrete generations, where neutral mutations occur among a finite set of possible alleles. In this model, each mutant child acquires a type…
We provide a sharp nonasymptotic analysis of the rates of convergence for some standard multivariate Markov chains using spectral techniques. All chains under consideration have multivariate orthogonal polynomial as eigenfunctions. Our…
In this article, a biallelic reversible mutation model with linear and quadratic selection is analyzed. The approach reconnects to one proposed by Kimura ( Possibility of extensive neutral evolution under stabilizing selection with special…
This paper gives a new flavor of what Peter Jagers and his co-authors call `the path to extinction'. In a neutral population with constant size $N$, we assume that each individual at time $0$ carries a distinct type, or allele. We consider…
We introduce a continuous-time Markov chain describing dynamic allelic partitions which extends the branching process construction of the Pitman sampling formula in Pitman (2006) and the birth-and-death process with immigration studied in…
We consider two versions of stochastic population models with mutation and selection. The first approach relies on a multitype branching process; here, individuals reproduce and change type (i.e., mutate) independently of each other,…
We study the evolution of the population genealogy in the classic neutral Moran Model of finite size and in discrete time. The stochastic transformations that shape a Moran population can be realized directly on its genealogy and give rise…
We consider a multi-type Moran model (in continuous time) with selection and type-dependent mutation. This paper is concerned with the evolution of genealogical information forward in time. For this purpose we define and analytically…
We introduce a unified operator-theoretic framework for analyzing mixing times of finite-state ergodic Markov chains that applies to both reversible and non-reversible dynamics. The central object in our analysis is the projected transition…
We consider a Moran model with two allelic types, mutation and selection. In this work, we study the behaviour of the proportion of fit individuals when the size of the population tends to infinity, without any rescaling of parameters or…
We construct an individual-based metapopulation model of population genetics featuring migration, mutation, selection and genetic drift. In the case of a single `island', the model reduces to the Moran model. Using the diffusion…
We study a general setting of neutral evolution in which the population is of finite, constant size and can have spatial structure. Mutation leads to different genetic types ("traits"), which can be discrete or continuous. Under minimal…
We study the fixation probability for two versions of the Moran process on the random graph $G_{n,p}$ at the threshold for connectivity. The Moran process models the spread of a mutant population in a network. Throughtout the process there…
We consider a general class of discrete, two-dimensional Markov chains modeling the dynamics of a population with two types, without mutation or immigration, and neutral in the sense that type has no influence on each individual's birth or…