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Cone-beam CT (CBCT) is installed in the treatment room to facilitate online clinical applications, including image guidance in radiation and surgery. Half-fan and short-can are the commonly used modes in clinical applications to expand the…

Medical Physics · Physics 2022-05-24 Junbo Peng

Current self-supervised denoising methods for paired noisy images typically involve mapping one noisy image through the network to the other noisy image. However, after measuring the spectral bias of such methods using our proposed Image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Wang Zhang , Huaqiu Li , Xiaowan Hu , Tao Jiang , Zikang Chen , Haoqian Wang

The characteristics of an x-ray spectrum can greatly influence imaging and related tasks. In practice, due to the pile-up effect of the detector, it's difficult to directly measure the spectrum of a CT scanner using an energy resolved…

Medical Physics · Physics 2015-03-09 Wei Zhao , Kai Niu , Sebastian Schafer , Kevin Royalty

The potential huge advantage of spectral computed tomography (CT) is its capability to provide accuracy material identification and quantitative tissue information. This can benefit clinical applications, such as brain angiography, early…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Weiwen Wu , Haijun Yu , Peijun Chen , Fulin Luo , Fenglin Liu , Qian Wang , Yining Zhu , Yanbo Zhang , Jian Feng , Hengyong Yu

Spectral imaging is the acquisition of multiple images of an object at different energy spectra. In mammography, dual-energy imaging (spectral imaging with two energy levels) has been investigated for several applications, in particular…

Medical Physics · Physics 2021-02-02 Karl Berggren , Mats Danielsson , Erik Fredenberg

Chemical imaging provides information about the distribution of chemicals within a target. When combined with structural information about the target, in situ chemical imaging opens the door to applications ranging from tissue…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Luke Pfister , Rohit Bhargava , Yoram Bresler , P. Scott Carney

Multi-contrast images are commonly acquired together to maximize complementary diagnostic information, albeit at the expense of longer scan times. A time-efficient strategy to acquire high-quality multi-contrast images is to accelerate…

Low fluence illumination sources can facilitate clinical transition of photoacoustic imaging because they are rugged, portable, affordable, and safe. However, these sources also decrease image quality due to their low fluence. Here, we…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Ali Hariri , Kamran Alipour , Yash Mantri , Jurgen P. Schulze , Jesse V. Jokerst

In Europe the 20% of the CT scans cover the thoracic region. The acquired images contain information about the cardiovascular system that often remains latent due to the lack of contrast in the cardiac area. On the other hand, the contrast…

Computer Vision and Pattern Recognition · Computer Science 2018-07-06 Gianmarco Santini , Lorena M. Zumbo , Nicola Martini , Gabriele Valvano , Andrea Leo , Andrea Ripoli , Francesco Avogliero , Dante Chiappino , Daniele Della Latta

Hybrid spectral CT integrates energy integrating detectors (EID) and photon counting detectors (PCD) into a single system, combining the large field-of-view advantage of EID with the high energy and spatial resolution of PCD. This…

Medical Physics · Physics 2024-10-25 Huiying Pan , Jianing Sun , Xu Jiang , Xing Zhao

Image denoising of low-dose computed tomography (LDCT) is an important problem for clinical diagnosis with reduced radiation exposure. Previous methods are mostly trained with pairs of synthetic or misaligned LDCT and normal-dose CT (NDCT)…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Junhao Long , Fengwei Yang , Juncheng Yan , Baoping Zhang , Chao Jin , Jian Yang , Changliang Zou , Jun Xu

Thermal ablation procedures, such as high intensity focused ultrasound (HIFU) and Radiofrequency Ablation (RFA), are often used to eliminate tumors by minimally invasively heating a focal region. For this task, real-time 3D temperature…

Medical Physics · Physics 2023-01-18 Nathan Wang , Mengzhou Li , Petteri Haverinen

Image reconstruction from computed tomography (CT) measurement is a challenging statistical inverse problem since a high-dimensional conditional distribution needs to be estimated. Based on training data obtained from high-quality…

Image and Video Processing · Electrical Eng. & Systems 2020-06-12 Alexander Denker , Maximilian Schmidt , Johannes Leuschner , Peter Maass , Jens Behrmann

In spectral CT reconstruction, the basis materials decomposition involves solving a large-scale nonlinear system of integral equations, which is highly ill-posed mathematically. This paper proposes a model that parameterizes the attenuation…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Ligen Shi , Ping Yang , Chang Liu , Wei Zhang , Xing Zhao , Jun Qiu

Objective. Dual-energy computed tomography (DECT) has the potential to improve contrast, reduce artifacts and the ability to perform material decomposition in advanced imaging applications. The increased number or measurements results with…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Alessandro Perelli , Suxer Alfonso Garcia , Alexandre Bousse , Jean-Pierre Tasu , Nikolaos Efthimiadis , Dimitris Visvikis

Spectral computed tomography (CT) offers the possibility to reconstruct attenuation images at different energy levels, which can be then used for material decomposition. However, traditional methods reconstruct each energy bin individually…

Deep learning approaches to the segmentation of magnetic resonance images have shown significant promise in automating the quantitative analysis of brain images. However, a continuing challenge has been its sensitivity to the variability of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dzung L. Pham , Yi-Yu Chou , Blake E. Dewey , Daniel S. Reich , John A. Butman , Snehashis Roy

Hyperspectral cameras face harsh trade-offs between spatial, spectral, and temporal resolution in inherently low-photon conditions. Computational imaging systems break through these trade-offs with compressive sensing, but have required…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 M. Kerem Aydin , Yi-Chun Hung , Jaclyn Pytlarz , Qi Guo , Emma Alexander

CT protocol design and quality control would benefit from automated tools to estimate the quality of generated CT images. These tools could be used to identify erroneous CT acquisitions or refine protocols to achieve certain signal to noise…

Computer Vision and Pattern Recognition · Computer Science 2016-10-25 Sohini Roychowdhury , Nathan Hollraft , Adam Alessio

The analysis of multi-modality positron emission tomography and computed tomography (PET-CT) images for computer aided diagnosis applications requires combining the sensitivity of PET to detect abnormal regions with anatomical localization…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim