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Related papers: EpidemiOptim: A Toolbox for the Optimization of Co…

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Augmentation of disease diagnosis and decision-making in healthcare with machine learning algorithms is gaining much impetus in recent years. In particular, in the current epidemiological situation caused by COVID-19 pandemic, swift and…

Computers and Society · Computer Science 2021-02-23 Leopold Franz , Yash Raj Shrestha , Bibek Paudel

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

Populations and Evolution · Quantitative Biology 2020-05-04 Andrew Lesniewski

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

World models have emerged as a unifying paradigm for learning latent dynamics, simulating counterfactual futures, and supporting planning under uncertainty. In this paper, we argue that computational epidemiology is a natural and…

Machine Learning · Computer Science 2026-04-14 Zeeshan Memon , Yiqi Su , Christo Kurisummoottil Thomas , Walid Saad , Liang Zhao , Naren Ramakrishnan

Mathematical optimization is one of the cornerstones of modern engineering research and practice. Yet, throughout all application domains, mathematical optimization is, for the most part, considered to be a numerical discipline.…

Optimization and Control · Mathematics 2024-01-09 Adrian Hauswirth , Zhiyu He , Saverio Bolognani , Gabriela Hug , Florian Dörfler

As a common strategy of contagious disease containment, lockdowns will inevitably weaken the economy. The ongoing COVID-19 pandemic underscores the trade-off arising from public health and economic cost. An optimal lockdown policy to…

Optimization and Control · Mathematics 2022-01-26 Qianqian Ma , Yang-Yu Liu , Alex Olshevsky

Non-pharmaceutical interventions (NPIs), such as diagnostic testing and quarantine, are crucial for controlling infectious disease outbreaks but are often constrained by limited resources, particularly in early outbreak stages. In…

Machine Learning · Computer Science 2026-05-04 Xueqiao Peng , Andrew Perrault

Dynamic Optimization Problems (DOPs) are challenging to address due to their complex nature, i.e., dynamic environment variation. Evolutionary Computation methods are generally advantaged in solving DOPs since they resemble dynamic…

Neural and Evolutionary Computing · Computer Science 2026-02-02 Zijian Gao , Yuanting Zhong , Zeyuan Ma , Yue-Jiao Gong , Hongshu Guo

Providing accurate and reliable predictions about the future of an epidemic is an important problem for enabling informed public health decisions. Recent works have shown that leveraging data-driven solutions that utilize advances in deep…

Machine Learning · Computer Science 2023-11-21 Harshavardhan Kamarthi , B. Aditya Prakash

In practice, the parameters of control policies are often tuned manually. This is time-consuming and frustrating. Reinforcement learning is a promising alternative that aims to automate this process, yet often requires too many experiments…

Infectious diseases remain among the top contributors to human illness and death worldwide, among which many diseases produce epidemic waves of infection. The unavailability of specific drugs and ready-to-use vaccines to prevent most of…

Machine Learning · Computer Science 2023-07-18 Madhurima Panja , Tanujit Chakraborty , Uttam Kumar , Nan Liu

Evolution sculpts both the body plans and nervous systems of agents together over time. In contrast, in AI and robotics, a robot's body plan is usually designed by hand, and control policies are then optimized for that fixed design. The…

Artificial Intelligence · Computer Science 2017-12-14 Nick Cheney , Josh Bongard , Vytas SunSpiral , Hod Lipson

Clinician scheduling remains a persistent challenge due to limited clinical resources and fluctuating demands. This complexity is especially acute in large academic anesthesiology departments as physicians balance responsibilities across…

Optimization and Control · Mathematics 2025-10-03 Anjali Jha , Wanqing Chen , Maxim Eckmann , Ian Stockwell , Jianwu Wang , Kai Sun

Artificial intelligence (AI) has become a powerful tool for economic research, enabling large-scale simulation and policy optimization. However, applying AI effectively requires simulation platforms for scalable training and evaluation-yet…

General Economics · Economics 2025-06-17 Qirui Mi , Qipeng Yang , Zijun Fan , Wentian Fan , Heyang Ma , Chengdong Ma , Siyu Xia , Bo An , Jun Wang , Haifeng Zhang

Reinforcement learning for control over continuous spaces typically uses high-entropy stochastic policies, such as Gaussian distributions, for local exploration and estimating policy gradient to optimize performance. Many robotic control…

Machine Learning · Computer Science 2024-04-03 Ya-Chien Chang , Sicun Gao

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

This study offers a new paradigm of individual-level modeling to address the grand challenge of incorporating human behavior in epidemic models. Using generative artificial intelligence in an agent-based epidemic model, each agent is…

Artificial Intelligence · Computer Science 2023-07-12 Ross Williams , Niyousha Hosseinichimeh , Aritra Majumdar , Navid Ghaffarzadegan

Aim of this paper is the description of a new tool to support institutions in the implementation of targeted countermeasures, based on quantitative and multi-scale elements, for the fight and prevention of emergencies, such as the current…

Computers and Society · Computer Science 2020-11-12 A. Sebastianelli , F. Mauro , G. Di Cosmo , F. Passarini , M. Carminati , S. L. Ullo

During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…

Populations and Evolution · Quantitative Biology 2021-04-28 Joseph Samuel , Supurna Sinha

Optimization modeling underlies critical decision-making across industries, yet remains difficult to automate: natural-language problem descriptions must be translated into precise mathematical formulations and executable solver code.…