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Designing reward functions for reinforcement learning (RL) in healthcare remains challenging because clinically meaningful outcomes are sparse, delayed, and difficult to explicitly specify. Although structured clinical data capture…

Artificial Intelligence · Computer Science 2026-05-26 Daniel J. Tan , Jayne Hui Zhen Chan , Kai Wen Hwang , Arturo Yong Yao Neo , Kay Choong See , Mengling Feng

Reinforcement learning agents are fundamentally limited by the quality of the reward functions they learn from, yet reward design is often overlooked under the assumption that a well-defined reward is readily available. However, in…

Reinforcement learning (RL) is concerned with how intelligence agents take actions in a given environment to maximize the cumulative reward they receive. In healthcare, applying RL algorithms could assist patients in improving their health…

Machine Learning · Statistics 2025-04-21 Chengchun Shi

As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often…

Machine Learning · Computer Science 2022-06-30 Yuqing Wang , Yun Zhao , Linda Petzold

Modern power systems are experiencing a variety of challenges driven by renewable energy, which calls for developing novel dispatch methods such as reinforcement learning (RL). Evaluation of these methods as well as the RL agents are…

Systems and Control · Electrical Eng. & Systems 2022-09-22 Zekuan Yu , Guangchun Ruan , Xinyue Wang , Guanglun Zhang , Yiliu He , Haiwang Zhong

Prescriptive process monitoring methods seek to optimize the performance of business processes by triggering interventions at runtime, thereby increasing the probability of positive case outcomes. These interventions are triggered according…

Artificial Intelligence · Computer Science 2025-05-20 Mahmoud Shoush , Marlon Dumas

Training agents to operate under strict constraints during deployment, such as limited resource budgets or stringent safety requirements, presents significant challenges, especially when these constraints render the task complex. In this…

Machine Learning · Computer Science 2025-11-05 Georgios Tzannetos , Parameswaran Kamalaruban , Adish Singla

Model-based reinforcement learning (MBRL) has demonstrated superior sample efficiency compared to model-free reinforcement learning (MFRL). However, the presence of inaccurate models can introduce biases during policy learning, resulting in…

Machine Learning · Computer Science 2025-03-27 Yongshuai Liu , Xin Liu

Reinforcement learning (RL) has become a promising approach to developing controllers for quadrupedal robots. Conventionally, an RL design for locomotion follows a position-based paradigm, wherein an RL policy outputs target joint positions…

Robotics · Computer Science 2023-03-14 Shuxiao Chen , Bike Zhang , Mark W. Mueller , Akshara Rai , Koushil Sreenath

Reinforcement learning (RL) agents improve through trial-and-error, but when reward is sparse and the agent cannot discover successful action sequences, learning stagnates. This has been a notable problem in training deep RL agents to…

Artificial Intelligence · Computer Science 2018-02-27 Evan Zheran Liu , Kelvin Guu , Panupong Pasupat , Tianlin Shi , Percy Liang

We present a unified model-based and data-driven approach for quadrupedal planning and control to achieve dynamic locomotion over uneven terrain. We utilize on-board proprioceptive and exteroceptive feedback to map sensory information and…

Robotics · Computer Science 2022-05-13 Siddhant Gangapurwala , Mathieu Geisert , Romeo Orsolino , Maurice Fallon , Ioannis Havoutis

Reinforcement learning (RL) has demonstrated its ability to solve high dimensional tasks by leveraging non-linear function approximators. However, these successes are mostly achieved by 'black-box' policies in simulated domains. When…

Machine Learning · Computer Science 2021-11-19 Riad Akrour , Davide Tateo , Jan Peters

Classical reinforcement learning (RL) techniques are generally concerned with the design of decision-making policies driven by the maximisation of the expected outcome. Nevertheless, this approach does not take into consideration the…

Machine Learning · Computer Science 2023-01-02 Thibaut Théate , Damien Ernst

Reinforcement learning (RL) is a general framework for adaptive control, which has proven to be efficient in many domains, e.g., board games, video games or autonomous vehicles. In such problems, an agent faces a sequential decision-making…

Machine Learning · Computer Science 2020-06-16 Olivier Buffet , Olivier Pietquin , Paul Weng

Randomized controlled trials typically analyze the effectiveness of treatments with the goal of making treatment recommendations for patient subgroups. With the advance of electronic health records, a great variety of data has been…

Machine Learning · Computer Science 2021-03-31 Zhiliang Wu , Yinchong Yang , Yunpu Ma , Yushan Liu , Rui Zhao , Michael Moor , Volker Tresp

In order for humans to confidently decide where to employ RL agents for real-world tasks, a human developer must validate that the agent will perform well at test-time. Some policy interpretability methods facilitate this by capturing the…

Machine Learning · Computer Science 2022-03-22 Julius Frost , Olivia Watkins , Eric Weiner , Pieter Abbeel , Trevor Darrell , Bryan Plummer , Kate Saenko

Self-driving vehicles must be able to act intelligently in diverse and difficult environments, marked by high-dimensional state spaces, a myriad of optimization objectives and complex behaviors. Traditionally, classical optimization and…

Robotics · Computer Science 2020-11-11 Josiah Coad , Zhiqian Qiao , John M. Dolan

Reinforcement learning (RL) in healthcare has had mixed results, with reward sparsity, unreliable off-policy evaluation, and deployment-simulation gap as recurring failure modes. We argue that chronic disease management is structurally a…

Machine Learning · Computer Science 2026-05-12 Prabhjot Singh , Abhishek Gupta , Chris Betz , Abe Flansburg , Brett Ives , Sudeep Lama , Jung Hoon Son

Modern deep architectures often rely on large-scale datasets, but training on these datasets incurs high computational and storage overhead. Real-world datasets often contain substantial redundancies, prompting the need for more…

Machine Learning · Computer Science 2025-06-27 Suorong Yang , Peijia Li , Furao Shen , Jian Zhao

Model-based reinforcement learning (RL) has shown great potential in various control tasks in terms of both sample-efficiency and final performance. However, learning a generalizable dynamics model robust to changes in dynamics remains a…

Machine Learning · Computer Science 2020-10-27 Younggyo Seo , Kimin Lee , Ignasi Clavera , Thanard Kurutach , Jinwoo Shin , Pieter Abbeel
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