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Reinforcement learning (RL) is a promising approach to generate treatment policies for sepsis patients in intensive care. While retrospective evaluation metrics show decreased mortality when these policies are followed, studies with…

Machine Learning · Computer Science 2024-04-11 Unnseo Park , Venkatesh Sivaraman , Adam Perer

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned…

Our aim is to establish a framework where reinforcement learning (RL) of optimizing interventions retrospectively allows us a regulatory compliant pathway to prospective clinical testing of the learned policies in a clinical deployment. We…

Machine Learning · Computer Science 2020-03-20 Luchen Li , Ignacio Albert-Smet , Aldo A. Faisal

A key barrier to using reinforcement learning (RL) in many real-world applications is the requirement of a large number of system interactions to learn a good control policy. Off-policy and Offline RL methods have been proposed to reduce…

Machine Learning · Computer Science 2022-12-02 Wenqi Cui , Linbin Huang , Weiwei Yang , Baosen Zhang

Many potential applications of reinforcement learning (RL) are stymied by the large numbers of samples required to learn an effective policy. This is especially true when applying RL to real-world control tasks, e.g. in the sciences or…

Machine Learning · Computer Science 2022-10-11 Viraj Mehta , Ian Char , Joseph Abbate , Rory Conlin , Mark D. Boyer , Stefano Ermon , Jeff Schneider , Willie Neiswanger

Offline safe reinforcement learning (RL) has emerged as a promising approach for learning safe behaviors without engaging in risky online interactions with the environment. Most existing methods in offline safe RL rely on cost constraints…

Machine Learning · Computer Science 2025-04-22 Ze Gong , Akshat Kumar , Pradeep Varakantham

Sepsis is a dangerous condition that is a leading cause of patient mortality. Treating sepsis is highly challenging, because individual patients respond very differently to medical interventions and there is no universally agreed-upon…

Machine Learning · Computer Science 2018-11-28 Aniruddh Raghu , Matthieu Komorowski , Sumeetpal Singh

Reinforcement Learning (RL) is a computational approach to reward-driven learning in sequential decision problems. It implements the discovery of optimal actions by learning from an agent interacting with an environment rather than from…

Methodology · Statistics 2022-10-06 Mauricio Tec , Yunshan Duan , Peter Müller

Reinforcement learning (RL) can be formulated as a sequence modeling problem, where models predict future actions based on historical state-action-reward sequences. Current approaches typically require long trajectory sequences to model the…

Machine Learning · Computer Science 2024-12-23 Hemant Kumawat , Saibal Mukhopadhyay

Conventional trajectory planning approaches for autonomous racing are based on the sequential execution of prediction of the opposing vehicles and subsequent trajectory planning for the ego vehicle. If the opposing vehicles do not react to…

Robotics · Computer Science 2024-07-26 Levent Ögretmen , Mo Chen , Phillip Pitschi , Boris Lohmann

As a subfield of machine learning, reinforcement learning (RL) aims at empowering one's capabilities in behavioural decision making by using interaction experience with the world and an evaluative feedback. Unlike traditional supervised…

Machine Learning · Computer Science 2020-04-27 Chao Yu , Jiming Liu , Shamim Nemati

Inverse reinforcement learning (IRL) aims to learn a reward function and a corresponding policy that best fit the demonstrated trajectories of an expert. However, current IRL works cannot learn incrementally from an ongoing trajectory…

Machine Learning · Computer Science 2025-07-24 Shicheng Liu , Minghui Zhu

As Reinforcement Learning (RL) agents are increasingly deployed in real-world applications, ensuring their behavior is transparent and trustworthy is paramount. A key component of trust is explainability, yet much of the work in Explainable…

Machine Learning · Computer Science 2025-12-09 Clifford F , Devika Jay , Abhishek Sarkar , Satheesh K Perepu , Santhosh G S , Kaushik Dey , Balaraman Ravindran

Sequential decision making under uncertainty is central to many Process Systems Engineering (PSE) challenges, where traditional methods often face limitations related to controlling and optimizing complex and stochastic systems.…

Systems and Control · Electrical Eng. & Systems 2025-10-29 Maximilian Bloor , Max Mowbray , Ehecatl Antonio Del Rio Chanona , Calvin Tsay

The deployment of reinforcement learning (RL) in the real world comes with challenges in calibrating user trust and expectations. As a step toward developing RL systems that are able to communicate their competencies, we present a method of…

Machine Learning · Computer Science 2020-11-19 Aastha Acharya , Rebecca Russell , Nisar R. Ahmed

In the rapidly changing healthcare landscape, the implementation of offline reinforcement learning (RL) in dynamic treatment regimes (DTRs) presents a mix of unprecedented opportunities and challenges. This position paper offers a critical…

Machine Learning · Computer Science 2024-06-05 Zhiyao Luo , Yangchen Pan , Peter Watkinson , Tingting Zhu

Reinforcement learning (RL) has increasingly become a pivotal technique in the post-training of large language models (LLMs). The effective exploration of the output space is essential for the success of RL. We observe that for complex…

Machine Learning · Computer Science 2025-07-08 Shihan Dou , Muling Wu , Jingwen Xu , Rui Zheng , Tao Gui , Qi Zhang , Xuanjing Huang

Although deep reinforcement learning has become a promising machine learning approach for sequential decision-making problems, it is still not mature enough for high-stake domains such as autonomous driving or medical applications. In such…

Machine Learning · Computer Science 2022-02-25 Claire Glanois , Paul Weng , Matthieu Zimmer , Dong Li , Tianpei Yang , Jianye Hao , Wulong Liu

This paper demonstrates that continual relearning of control policies using incremental deep reinforcement learning (RL) can improve policy learning for non-stationary processes. We demonstrate this approach for a data-driven 'smart…

Machine Learning · Computer Science 2020-08-06 Avisek Naug , Marcos Quiñones-Grueiro , Gautam Biswas

We study reinforcement learning (RL) problems in which agents observe the reward or transition realizations at their current state before deciding which action to take. Such observations are available in many applications, including…

Machine Learning · Computer Science 2024-10-22 Nadav Merlis
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