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Antigenic variation is the main immune escape mechanism for RNA viruses like influenza or SARS-CoV-2. While high mutation rates promote antigenic escape, they also induce large mutational loads and reduced fitness. It remains unclear how…

Populations and Evolution · Quantitative Biology 2023-07-24 Victor Chardès , Andrea Mazzolini , Thierry Mora , Aleksandra M. Walczak

The conformation space of a 20-residue antiparallel $\beta$-sheet peptide, sampled by molecular dynamics simulations, is mapped to a network. Conformations are nodes of the network, and the transitions between them are links. The…

Biomolecules · Quantitative Biology 2007-05-23 Francesco Rao , Amedeo Caflisch

Surface plasmon resonance (SPR)-based biosensors are widely used instruments for characterizing molecular interactions. In theory the SPR signal depends only on mass changes for interacting molecules of same chemical nature. Whether…

Biomolecules · Quantitative Biology 2023-04-12 Daniel Dobrovodský , Carmelo Di Primo

A recent theory of the disorder-dependent slope of the upper critical field, $H_{c2}$, at the superconducting transition temperature, $T_{c}$, is extended to multiband superconductors aiming at iron-based superconductors, considering two…

Superconductivity · Physics 2024-11-28 R. Prozorov , V. G. Kogan , M. Konczykowski , M. A. Tanatar

In allosteric proteins, binding a ligand can affect function at a distant location, for example by changing the binding affinity of a substrate at the active site. The induced fit and population shift models, which differ by the assumed…

Biological Physics · Physics 2019-10-28 Riccardo Ravasio , Solange Flatt , Le Yan , Stefano Zamuner , Carolina Brito , Matthieu Wyart

We study two-component Bose gases with Raman induced spin-orbit coupling via a perturbation approach at finite temperature. For weak coupling, free energy is expanded in terms of Raman coupling strength up to the second order, where the…

Quantum Gases · Physics 2016-04-01 Zeng-Qiang Yu

Doping Bi2Sr2Ca1Cu2O8+y with Co causes a superconductor-insulator transition. We study correlations between changes in the electrical resistivity RHOab(T) and the electronic bandstructure using identical single crystalline samples. For…

Condensed Matter · Physics 2009-10-22 C. Quitmann , P. Almeras , Jian Ma , R. J. Kelley , H. Berger , G. Margaritondo , M. Onellion

We study the origin of the cooperative nature of spin crossover (SC) between low spin (LS) and high spin (HS) states from the view point of elastic interactions among molecules. As the size of each molecule changes depending on its spin…

Strongly Correlated Electrons · Physics 2009-11-13 Masamichi Nishino , Kamel Boukheddaden , Yusuké Konishi , Seiji Miyashita

There is increasing evidence that infection with SARS-CoV-2 can cause a spectrum of neurological symptoms. In this paper, we develop a theoretical concept underlying such neurological COVID-19 consequences by employing a non-equilibrium…

Medical Physics · Physics 2021-11-09 Umberto Lucia , Giulia Grisolia , Thomas S. Deisboeck

We have studied the temperature dependence of resistivity, $\rho$, for a two-dimensional electron system in silicon at low electron densities, $n_s\sim10^{11}$ cm$^{-2}$, near the metal/insulator transition. The resistivity was empirically…

Condensed Matter · Physics 2007-05-23 S. V. Kravchenko , Whitney E. Mason , G. E. Bowker , J. E. Furneaux , V. M. Pudalov , M. D'Iorio

The importance of torsion vibration in the transmission of life information is indicated. The localization of quantum torsion state is proved. Following these analyses a formalism on the quantum theory of conformation-electron system is…

Biomolecules · Quantitative Biology 2009-06-16 Liaofu Luo

Background: Network propagation has been widely used for nearly 20 years to predict gene functions and phenotypes. Despite the popularity of this approach, little attention has been paid to the question of provenance tracing in this…

The kagome lattice is very attractive as it can host many novel quantum states, such as the charge density wave, superconductivity, quantum spin liquid, etc. Meanwhile, iridates often exhibit a strong spin-orbit coupling (SOC) effect due to…

Superconductivity · Physics 2024-12-02 Zhengyan Zhu , Yuxiang Wu , Shengtai Fan , Yiliang Fan , Yiwen Li , Yongze Ye , Xiyu Zhu , Haijun Zhang , Hai-Hu Wen

The structure of CO adsorbates on the Rh(110) surface is studied at full coverage using first-principles techniques. The relative energies of different adsorbate geometries are determined by means of accurate structure optimizations. In…

Materials Science · Physics 2009-10-28 Dario Alfe' , Stefano Baroni

Static and dynamical properties of elastic phase transitions under the influence of short--range defects, which locally increase the transition temperature, are investigated. Our approach is based on a Ginzburg--Landau theory for…

Condensed Matter · Physics 2016-08-31 M. Bulenda , F. Schwabl , U. C. Täuber

The COVID-19 pandemic exposed critical gaps in our ability to predict viral emergence and trajectory. Moving beyond sequence-dependent surveillance, we introduce V-Reactor Dynamics, a physics-based framework that models host-virus…

Biological Physics · Physics 2026-02-06 Yong-Shou Chen

The local structures of 122-type paradium arsenides, namely BaPd$_2$As$_2$ and SrPd$_2$As$_2$, are examined by As K-edge extended x-ray absorption fine structure measurements to find a possible correlation between the variation of their…

The susceptible-infectious-recovered (SIR) model describes the evolution of three species of individuals which are subject to an infection and recovery mechanism. A susceptible $S$ can become infectious with an infection rate $\beta$ by an…

Statistical Mechanics · Physics 2008-06-30 Gunter M. Schütz , Marian Brandau , Steffen Trimper

The accurate knowledge of the elastic properties of single-stranded DNA (ssDNA) is key to characterize the thermodynamics of molecular reactions that are studied by force spectroscopy methods where DNA is mechanically unfolded. Examples…

Soft Condensed Matter · Physics 2021-10-19 X. Viader-Godoy , M. Manosas , F. Ritort

The two-dimensional electron gas found at the surface of SrTiO$_3$ and related interfaces has attracted significant attention as a promising basis for oxide electronics. In order to utilize its full potential, the response of this 2DEG to…