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We describe a system for interrogating the acoustic properties of sub-nanoliter liquid samples within an open microfluidics platform. Sessile droplets were deposited onto integrated optomechanical sensors, which possess…

Applied Physics · Physics 2023-07-17 Kyle G. Scheuer , Franz B. Romero , Graham J. Hornig , Ray G. DeCorby

Large-scale astronomical surveys can capture numerous images of celestial objects, including galaxies and nebulae. Analysing and processing these images can reveal intricate internal structures of these objects, allowing researchers to…

Instrumentation and Methods for Astrophysics · Physics 2023-11-02 Peng Jia , Jiameng Lv , Runyu Ning , Yu Song , Nan Li , Kaifan Ji , Chenzhou Cui , Shanshan Li

Photoacoustic microscopy (PAM) is an emerging imaging method combining light and sound. However, limited by the laser's repetition rate, state-of-the-art high-speed PAM technology often sacrifices spatial sampling density (i.e.,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Tri Vu , Anthony DiSpirito , Daiwei Li , Zixuan Zhang , Xiaoyi Zhu , Maomao Chen , Laiming Jiang , Dong Zhang , Jianwen Luo , Yu Shrike Zhang , Qifa Zhou , Roarke Horstmeyer , Junjie Yao

Construction of in vitro vascular models is of great significance to various biomedical research, such as pharmacokinetics and hemodynamics, thus is an important direction in tissue engineering. In this work, a standing surface acoustic…

Medical Physics · Physics 2023-08-21 Yue Wu , Yuwen Zhao , Khayrul Islam , Yuyuan Zhou , Saeed Omidi , Yevgeny Berdichevsky , Yaling Liu

We propose an orbital angular momentum (OAM) quantum holography scheme based on multi-mode Bessel-Gaussian (MBG) beams. Entangled photon pairs are generated through spontaneous parametric down-conversion (SPDC) process, and the axis prism…

Optics · Physics 2026-04-29 Jinjin Li , Chaoying Zhao

Accurate MR signal simulation, including microvascular structures and water diffusion, is crucial for MRI techniques like fMRI BOLD modeling and MR vascular Fingerprinting (MRF), which use susceptibility effects on MR signals for tissue…

X-ray fluorescence computed tomography based on sheet-beam can save a huge amount of time to obtain a whole set of projections using synchrotron. However, it is clearly unpractical for most biomedical research laboratories. In this paper,…

Medical Physics · Physics 2017-03-07 Shanghai Jiang , Peng He , Luzhen Deng , Mianyi Chen , Biao Wei

Accurately estimating the point spread function (PSF) of an optical system requires solving free-space wave propagation, which entails evaluating a diffraction integral. This integral is traditionally computed numerically using Fast Fourier…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Nicholas Ganino , Qi Guo

We present a minimally-invasive endoscope based on a multimode fiber that combines photoacoustic and fluorescence sensing. From the measurement of a transmission matrix during a prior calibration step, a focused spot is produced and…

This study presents a new computational approach for simulating the microbial decomposition of organic matter, from 3D micro-computed tomography (micro-CT) images of soil. The method employs a valuated graph of connected voxels to simulate…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Mouad Klai , Olivier Monga , Mohamed Soufiane Jouini , Valérie Pot

We have developed an efficacious algorithm for simulation of the beam-beam interaction in synchrotron colliders based on the nonlinear $\delta f$ method, where $\delta f$ is the much smaller deviation of the beam distribution from the…

Accelerator Physics · Physics 2007-05-23 Yunhai Cai , Alexander W. Chao , Stephan I. Tzenov , Toshi Tajima

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Ultrasonic transducer is a sensor that realizes the mutual conversion of ultrasonic and electrical signals, and it is widely used in quality inspection, biomedical imaging and other fields. Commonly used ultrasonic transducers have a small…

Applied Physics · Physics 2020-10-06 Xianlin Song , Jianshuang Wei , Lingfang Song

There has been a longstanding expectation that the optical resolution embodiment of photoacoustic tomography could have a substantial impact on gastrointestinal endoscopy by enabling microscopic visualization of the vasculature based on the…

In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies. Typically blood flows…

Photoacoustic tomography (PAT) is a nonionizing imaging modality capable of acquiring high contrast and resolution images of optical absorption at depths greater than traditional optical imaging techniques. Practical considerations with…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Steven Guan , Amir A. Khan , Siddhartha Sikdar , Parag V. Chitnis

We developed Macular, a simulation platform with a graphical interface, designed to produce in silico experiment scenarios for the retina and the primary visual system. A scenario consists of generating a three-dimensional structure with…

In this paper we implement experimentally the spatial shape modelling of nondiffracting optical beams via computer generated holograms. The results reported here are the experimental confirmation of the so called Frozen Wave method,…

We report on a broader evaluation of statistical bootstrap resampling methods as a tool for pixel-level calibration and imaging fidelity assessment in radio interferometry. Pixel-level imaging fidelity assessment is a challenging problem,…

Instrumentation and Methods for Astrophysics · Physics 2015-05-14 Athol Kemball , Adam Martinsek , Modhurita Mitra , Hsin-Fang Chiang

The imaging depth of deep-tissue optical microscopy is governed by the performance of the gating operation that suppresses the multiply scattered waves obscuring the ballistic waves. Although various gating operations based on confocal,…