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We build a simulation platform for Airy beam photoacoustic microscopy based on K-Wave simulation toolbox in MATLAB. The sample was located in the middle of z direction in the environment. The propagation of Airy beam irradiated on the…

Biological Physics · Physics 2020-11-21 Xianlin Song , Ganyu Chen , Lingfang Song , Jianshuang Wei

Photoacoustic microscopy is becoming an important tool for the biomedical research. It has been widely used in biological researches, such as structural imaging of vasculature, brain structural and functional imaging, and tumor detection.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Xianlin Song , Jianshuang Wei , Lingfang Song

Interferometric scattering microscopy is a powerful technique that enables various applications, such as mass photometry and particle tracking. Here we present a numerical toolbox to simulate images obtained in interferometric scattering,…

Photoacoustic microscopy with large depth of focus is significant to the biomedical research. The conventional optical-resolution photoacoustic microscope (OR-PAM) suffers from limited depth of field (DoF) since the employed focused…

Image and Video Processing · Electrical Eng. & Systems 2020-09-07 Xianlin Song , Jianshuang Wei , Lingfang Song

Photoacoustic imaging has emerged in the past decades. Compared with the traditional medical imaging mode, it has better imaging performance and has great development potential in the field of biological imaging. In traditional…

Medical Physics · Physics 2020-09-03 Xianlin Song , Jianshuang Wei , Jianmin Xiong , Lingfang Song

Photoacoustic imaging has shown great promise for medical imaging, where optical energy absorption by blood haemoglobin is used as the contrast mechanism. A numerical method was developed for the in-silico assessment of the photoacoustic…

Medical Physics · Physics 2015-12-22 Kamyar Firouzi , Nader Saffari

Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…

Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

Optics · Physics 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

Speckle patterns are formed by random interferences of mutually coherent beams. While speckles are often considered as an unwanted noise in many areas, they also formed the foundation for the development of numerous speckle-based imaging,…

Optics · Physics 2022-07-26 Vijayakumar Anand

Sample-induced image-degradation remains an intricate wave-optical problem in light-sheet microscopy. Here we present biobeam, an open-source software package that enables to simulate operational light-sheet microscopes by combining data…

Biological Physics · Physics 2018-07-04 Martin Weigert , Eugene W. Myers , Moritz Kreysing

Non-invasive stimulation of small, variably shaped brain sub-regions is crucial for advancing our understanding of brain functions. Current ultrasound neuromodulation faces two significant trade-offs when targeting brain sub-regions:…

Neurons and Cognition · Quantitative Biology 2025-07-09 Yueming Li , Guo Chen , Tiago R. Oliveira , Nick Todd , Yong-Zhi Zhang , Carolyn Marar , Nan Zheng , Lu Lan , Nathan McDannold , Ji-Xin Cheng , Chen Yang

Light sheet fluorescence microscopy (LSFM) has transformed the way we visualize biological tissues in three dimensions, offering high-resolution imaging while minimizing photo-induced damage to the samples. Recent breakthroughs in…

Optics · Physics 2025-05-27 Alireza Tabatabaei Mashayekh , Jeremy Witzens

Photoacoustic imaging develops very fast in recent years due to its superior performance in many preclinical and clinical applications. However, it is still in a developing stage, and a lot of experiments have to be performed in a…

Medical Physics · Physics 2020-12-25 Jiadong Zhang , Tengbo Lyu , Changchun Yang , Yimeng Yang , Shanshan Guo , Feng Gao , Fei Gao

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is an emerging computed biomedical imaging modality that exploits optical contrast and ultrasonic detection principles. Iterative image reconstruction algorithms that…

Medical Physics · Physics 2016-11-17 Kun Wang , Robert W Schoonover , Richard Su , Alexander Oraevsky , Mark A Anastasio

We developed a Bessel light sheet fluorescence microscopy (LSFM) system to enable high-speed, wide-field intra-vital imaging of zebrafish and other thick biological samples. This system uses air objectives for the convenient mounting of…

Optics · Physics 2023-11-07 Chuhui Wang , Jiaju Chen , Cuiyi Peng , Zhenglin Chen , Dongmei Yu , Peiwu Qin

This article presents new numerical simulation tools, respectively developed in Matlab and Blender softwares. Available in open-source under the GPL 3.0 license, it uses a ray-tracing/image-sources hybrid method to calculate the room…

Audio and Speech Processing · Electrical Eng. & Systems 2018-11-15 Matthieu Aussal , Robin Gueguen

We propose and experimentally demonstrate femtosecond direct laser writing with Bessel beams for the fabrication of photonic crystals with spatial filtering functionality. Such filters are mechanically stable, of small (of order of…

Applied Physics · Physics 2019-10-23 Darius Gailevičius , Vytautas Purlys , Kestutis Staliunas

Current optoacoustic microscopy configurations often have narrow focal ranges that limit their use for fast volumetric imaging applications. Here, the focal range of optoacoustic microscopes is extended by matching the elongated optical…

Optics · Physics 2021-04-15 Zakiullah Ali , Christian Zakian , Vasilis Ntziachristos

Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore…

Optics · Physics 2026-01-06 David C. Garrett , Lihong V. Wang

Simulated images are essential in algorithm development and instrument testing for optical telescopes. During real observations, images obtained by optical telescopes are affected by spatially variable point spread functions (PSFs), a…

Instrumentation and Methods for Astrophysics · Physics 2025-02-17 Zeyu Bai , Peng Jia , Jiameng Lv , Xiang Zhang , Wennan Xiang , Lin Nie
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