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This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

Cryo-electron microscopy (cryo-EM) has become a tool of fundamental importance in structural biology, helping us understand the basic building blocks of life. The algorithmic challenge of cryo-EM is to jointly estimate the unknown 3D poses…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Axel Levy , Frédéric Poitevin , Julien Martel , Youssef Nashed , Ariana Peck , Nina Miolane , Daniel Ratner , Mike Dunne , Gordon Wetzstein

Cardiac Magnetic Resonance (CMR) imaging provides a comprehensive assessment of cardiac structure and function but remains constrained by high acquisition costs and reliance on expert annotations, limiting the availability of large-scale…

Image and Video Processing · Electrical Eng. & Systems 2026-02-11 Xiaocheng Fang , Zhengyao Ding , Guangkun Nie , Jieyi Cai , Yujie Xiao , Bo Liu , Jiarui Jin , Haoyu Wang , Shun Huang , Ting Chen , Hongyan Li , Shenda Hong

The high prevalence of cardiovascular diseases (CVDs) calls for accessible and cost-effective continuous cardiac monitoring tools. Despite Electrocardiography (ECG) being the gold standard, continuous monitoring remains a challenge, leading…

Signal Processing · Electrical Eng. & Systems 2023-12-29 Debaditya Shome , Pritam Sarkar , Ali Etemad

Automatic identification of proper image frames at the end-diastolic (ED) and end-systolic (ES) frames during the review of invasive coronary angiograms (ICA) is important to assess blood flow during a cardiac cycle, reconstruct the 3D…

Image and Video Processing · Electrical Eng. & Systems 2021-10-07 Yinghui Meng , Minghao Dong , Xumin Dai , Haipeng Tang , Chen Zhao , Jingfeng Jiang , Shun Xu , Ying Zhou , Fubao Zhu1 , Zhihui Xu , Weihua Zhou

Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

Accurate assessment of intraventricular blood flow is essential for evaluating hemodynamic conditions in patients supported by Left Ventricular Assist Devices (LVADs). However, clinical imaging is either incompatible with LVADs or yields…

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual…

Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…

Computational Engineering, Finance, and Science · Computer Science 2025-08-04 Haizhou Yang , Jiyang Zhang , Ismael Z. Assi , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

New-generation space missions require satellites to carry substantial amounts of liquid propellant, making it essential to analyse the coupled control-structure-propellant dynamics in detail. While Computational Fluid Dynamics (CFD) offers…

We present ECG-Expert-QA, a comprehensive multimodal dataset for evaluating diagnostic capabilities in electrocardiogram (ECG) interpretation. It combines real-world clinical ECG data with systematically generated synthetic cases, covering…

Signal Processing · Electrical Eng. & Systems 2025-04-08 Xu Wang , Jiaju Kang , Puyu Han , Yubao Zhao , Qian Liu , Liwenfei He , Lingqiong Zhang , Lingyun Dai , Yongcheng Wang , Jie Tao

The human heart is a complex system exhibiting stochastic nature, as reflected in electrocardiogram (ECG) signals. ECG signal is a weak, non-stationary, and nonlinear signal, which indicates the health of a heart in terms of temporal…

Signal Processing · Electrical Eng. & Systems 2020-02-11 Chiranjit Maji , Pratyay Sengupta , Anandi Batabyal , Hirok Chaudhuri

In the process of patient diagnosis, non-invasive measurements are widely used due to their low risks and quick results. Electrocardiogram (ECG), as a non-invasive method to collect heart activities, is used to diagnose cardiac conditions.…

Machine Learning · Computer Science 2025-12-11 Yuhao Xu , Jiaying Lu , Sirui Ding , Defu Cao , Xiao Hu , Carl Yang

Sudden cardiac death and arrhythmia account for a large percentage of all deaths worldwide. Electrocardiography (ECG) is the most widely used screening tool for cardiovascular diseases. Traditionally, ECG signals are classified manually,…

Signal Processing · Electrical Eng. & Systems 2022-06-16 Li Xiaolin , Fang Xiang , Rajesh C. Panicker , Barry Cardiff , Deepu John

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Background The development of a simulation model of full body reaching tasks that can predict endeffector trajectories and joint excursions consistent with experimental data is a non-trivial task. Because of the kinematic redundancy…

Systems and Control · Computer Science 2011-08-10 Daohang Sha , James S Thomas

Cryo-EM is a transformational paradigm in molecular biology where computational methods are used to infer 3D molecular structure at atomic resolution from extremely noisy 2D electron microscope images. At the forefront of research is how to…

Quantitative Methods · Quantitative Biology 2025-06-12 Shayan Shekarforoush , David B. Lindell , Marcus A. Brubaker , David J. Fleet

We propose a machine learning-based method to build a system of differential equations that approximates the dynamics of 3D electromechanical models for the human heart, accounting for the dependence on a set of parameters. Specifically,…

Numerical Analysis · Mathematics 2022-04-06 Francesco Regazzoni , Matteo Salvador , Luca Dedè , Alfio Quarteroni

Simultaneous electrocardiography (ECG) and phonocardiogram (PCG) provide a comprehensive, multimodal perspective on cardiac function by capturing the heart's electrical and mechanical activities, respectively. However, the distinct and…

Machine Learning · Computer Science 2025-06-13 Sajjad Karimi , Amit J. Shah , Gari D. Clifford , Reza Sameni

This study presents AI-HEART, a cloud-based information system for managing and analysing long-duration ambulatory electrocardiogram (ECG) recordings and supporting clinician decision-making. The platform operationalises an end-to-end…