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Computational models lie at the intersection of basic neuroscience and healthcare applications because they allow researchers to test hypotheses \textit{in silico} and predict the outcome of experiments and interactions that are very hard…

Neurons and Cognition · Quantitative Biology 2020-09-18 Katharina Glomb , Joana Cabral , Anna Cattani , Alberto Mazzoni , Ashish Raj , Benedetta Franceschiello

Deep learning models for pulmonary disease screening from Computed Tomography (CT) scans promise to alleviate the immense workload on radiologists. Still, their high computational cost, stemming from processing entire 3D volumes, remains a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Qian Shao , Bang Du , Yixuan Wu , Zepeng Li , Qiyuan Chen , Qianqian Tang , Jian Wu , Jintai Chen , Hongxia Xu

The introduction of computational models in cardiovascular sciences has been progressively bringing new and unique tools for the investigation of the physiopathology. Together with the dramatic improvement of imaging and measuring devices…

Electrocardiography (ECG) offers critical cardiovascular insights, such as identifying arrhythmias and myocardial ischemia, but enabling automated systems to answer complex clinical questions directly from ECG signals (ECG-QA) remains a…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Hung Manh Pham , Jialu Tang , Aaqib Saeed , Dong Ma

Cryo-electron microscopy (cryo-EM), the subject of the 2017 Nobel Prize in Chemistry, is a technology for determining the 3-D structure of macromolecules from many noisy 2-D projections of instances of these macromolecules, whose…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Roy R. Lederman , Joakim Andén , Amit Singer

In this work we propose to validate the predictive capabilities of one-dimensional (1D) blood flow models with full three-dimensional (3D) models in the context of patient-specific coronary hemodynamics in hyperemic conditions. Such…

Electrocardiogram (ECG) signals play critical roles in the clinical screening and diagnosis of many types of cardiovascular diseases. Despite deep neural networks that have been greatly facilitated computer-aided diagnosis (CAD) in many…

Machine Learning · Computer Science 2021-05-31 Jingyi Liu , Zhongyu Li , Xiayue Fan , Jintao Yan , Bolin Li , Xuemeng Hu , Qing Xia , Yue Wu

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Yundi Zhang , Chen Chen , Suprosanna Shit , Sophie Starck , Daniel Rueckert , Jiazhen Pan

Virtual heart models have been proposed to enhance the safety of implantable cardiac devices through closed loop validation. To communicate with a virtual heart, devices have been driven by cardiac signals at specific sites. As a result,…

Systems and Control · Computer Science 2017-03-06 Weiwei Ai , Nitish Patel , Partha Roop , Avinash Malik , Nathan Allen , Mark L. Trew

Cardiovascular diseases (CVD) are a predominant health concern globally, emphasizing the need for advanced diagnostic techniques. In our research, we present an avant-garde methodology that synergistically integrates ECG readings and…

Physical interactive robotics, ranging from wearable devices to collaborative humanoid robots, require close coordination between mechanical design and control. However, evaluating interactive dynamics is challenging due to complex human…

Robotics · Computer Science 2026-03-11 Chenhui Zuo , Jinhao Xu , Michael Qian Vergnolle , Yanan Sui

Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascular diseases. While 1-D arterial models offer an attractive compromise between…

This paper presents a comprehensive review of cardiorespiratory auscultation sensing devices (i.e., stethoscopes), which is useful for understanding the theoretical aspects and practical design notes. In this paper, we first introduce the…

Signal Processing · Electrical Eng. & Systems 2025-02-17 Yasaman Torabi , Shahram Shirani , James P. Reilly , Gail M Gauvreau

Accurate and efficient modeling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics (CFD)…

Fluid Dynamics · Physics 2025-07-30 Eneko Lazpita , Jesus Garicano-Mena , Soledad Le Clainche

Estimating the shape and motion state of the myocardium is essential in diagnosing cardiovascular diseases.However, cine magnetic resonance (CMR) imaging is dominated by 2D slices, whose large slice spacing challenges inter-slice shape…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Xiaohan Yuan , Cong Liu , Yangang Wang

Cardiac digital twins (CDTs) of human cardiac electrophysiology (EP) are digital replicas of patient hearts that match like-for-like clinical observations. The electrocardiogram (ECG), as the most prevalent non-invasive observation of…

Medical Physics · Physics 2024-07-26 Elena Zappon , Matthias A. F. Gsell , Karli Gillette , Gernot Plank

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Empirical Dynamic Modeling (EDM) is a nonlinear time series causal inference framework. The latest implementation of EDM, cppEDM, has only been used for small datasets due to computational cost. With the growth of data collection…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-24 Wassapon Watanakeesuntorn , Keichi Takahashi , Kohei Ichikawa , Joseph Park , George Sugihara , Ryousei Takano , Jason Haga , Gerald M. Pao

Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling is an important tool to fill this gap. Typical studies often employ detailed…

Tissues and Organs · Quantitative Biology 2022-03-08 R. V. Stenzinger , M. H. R. Tragtenberg
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