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Gene expression datasets are usually of high dimensionality and therefore require efficient and effective methods for identifying the relative importance of their attributes. Due to the huge size of the search space of the possible…

Machine Learning · Computer Science 2022-06-10 Fernando Jiménez , Gracia Sánchez , José Palma , Luis Miralles-Pechuán , Juan Botía

We consider the problem of inferring the values of an arbitrary set of variables (e.g., risk of diseases) given other observed variables (e.g., symptoms and diagnosed diseases) and high-dimensional signals (e.g., MRI images or EEG). This is…

Machine Learning · Statistics 2019-02-07 Hao Wang , Chengzhi Mao , Hao He , Mingmin Zhao , Tommi S. Jaakkola , Dina Katabi

After the completion of human genome sequence was anounced, it is evident that interpretation of DNA sequences is an immediate task to work on. For understanding their signals, improvement of present sequence analysis tools and developing…

Computational Complexity · Computer Science 2007-05-23 Gene Kim , MyungHo Kim

Persistence modules that decompose into interval modules are important in topological data analysis because we can interpret such intervals as the lifetime of topological features in the data. We can classify the settings in which…

Algebraic Topology · Mathematics 2025-01-03 Ángel Javier Alonso , Enhao Liu

This study introduces Bidirectional Topic Matching (BTM), a novel method for cross-corpus topic modeling that quantifies thematic overlap and divergence between corpora. BTM is a flexible framework that can incorporate various topic…

Computation and Language · Computer Science 2024-12-25 Raven Adam , Marie Lisa Kogler

Biclustering has gained interest in gene expression data analysis due to its ability to identify groups of samples that exhibit similar behaviour in specific subsets of genes (or vice versa), in contrast to traditional clustering methods…

Applications · Statistics 2024-12-12 Luis A. Vargas-Mieles , Paul D. W. Kirk , Chris Wallace

The standard paradigm for the analysis of genome-wide association studies involves carrying out association tests at both typed and imputed SNPs. These methods will not be optimal for detecting the signal of association at SNPs that are not…

Many bipartite networks exhibit hierarchical community structure, but existing community detection methods are not well-suited for detecting hierarchy. They also do not effectively handle weighted bipartite networks. In this work, we…

Social and Information Networks · Computer Science 2026-04-13 Tania Ghosh , Kevin E. Bassler

Bipartite networks, which encode interactions between two distinct types of entities, arise widely in applications and exhibit inherent asymmetry across node sets. Despite a growing literature on bipartite community detection, estimating…

Methodology · Statistics 2026-05-18 Bokai Yang , Yuanxing Chen , Yuhong Yang

Invariant prediction [Peters et al., 2016] analyzes feature/outcome data from multiple environments to identify invariant features - those with a stable predictive relationship to the outcome. Such features support generalization to new…

Machine Learning · Statistics 2025-07-10 Luhuan Wu , Mingzhang Yin , Yixin Wang , John P. Cunningham , David M. Blei

Recently, bipath persistent homology has been proposed as an extension of standard persistent homology, along with its visualization (bipath persistence diagram) and computational methods. In the setting of standard persistent homology, the…

Algebraic Topology · Mathematics 2025-03-04 Shunsuke Tada

Binary stellar evolution simulations are computationally expensive. Stellar population synthesis relies on these detailed evolution models at a fundamental level. Producing thousands of such models requires hundreds of CPU hours, but…

Many multiple testing procedures make use of the p-values from the individual pairs of hypothesis tests, and are valid if the p-value statistics are independent and uniformly distributed under the null hypotheses. However, it has recently…

Methodology · Statistics 2011-08-25 Joshua D. Habiger , Edsel A. Pena

Micro-panel data are collected and analysed in many research and industry areas. Cluster analysis of micro-panel data is an unsupervised learning exploratory method identifying subgroup clusters in a data set which include homogeneous…

Machine Learning · Statistics 2018-07-17 Lukas Sobisek , Maria Stachova , Jan Fojtik

Research data sets are growing to unprecedented sizes and network modeling is commonly used to extract complex relationships in diverse domains, such as genetic interactions involved in disease, logistics, and social communities. As the…

Social and Information Networks · Computer Science 2024-05-03 Sharlee Climer , Kenneth Smith , Wei Yang , Lisa de las Fuentes , Victor G. Dávila-Román , C. Charles Gu

Motivation: Modules in gene coexpression networks (GCN) can be regarded as gene groups with individual relationships. No studies have optimized module detection methods to extract diverse gene groups from GCN, especially for data from…

Molecular Networks · Quantitative Biology 2021-12-07 Iori Azuma , Tadahaya Mizuno , Hiroyuki Kusuhara

We demonstrate how the collective response of $N$ globally coupled bistable elements can strongly reflect the presence of very few non-identical elements in a large array of otherwise identical elements. Counter-intuitively, when there are…

Adaptation and Self-Organizing Systems · Physics 2012-10-10 Kamal P. Singh , Rajeev Kapri , Sudeshna Sinha

Weakly supervised text-to-person image matching, as a crucial approach to reducing models' reliance on large-scale manually labeled samples, holds significant research value. However, existing methods struggle to predict complex one-to-many…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Yafei Zhang , Yongle Shang , Huafeng Li

Being an unsupervised machine learning and data mining technique, biclustering and its multimodal extensions are becoming popular tools for analysing object-attribute data in different domains. Apart from conventional clustering techniques,…

Artificial Intelligence · Computer Science 2017-02-20 Dmitry I. Ignatov , Bruce W. Watson

In this work, we introduce bidirectional collision detection --- a new algorithmic tool that applies to the collision problems that arise in many isomorphism problems. For the group isomorphism problem, we show that bidirectional collision…

Data Structures and Algorithms · Computer Science 2013-05-17 David J. Rosenbaum
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