Related papers: Technical Note: A fast and monolithic prototype cl…
HollandPTC is an independent outpatient center for proton therapy, scientific research, and education. Patients with different types of cancer are treated with Intensity Modulated Proton Therapy (IMPT). In addition, the HollandPTC R&D…
For dose calculations in ion beam therapy, it is vital to accurately determine the relative stopping power (RSP) distribution within the treated volume. Currently, RSP values are extrapolated from Hounsfield units (HU), measured with x-ray…
Scintillating fibre detectors combine sub-mm resolution particle tracking, precise measurements of the particle stopping power and sub-ns time resolution. Typically, fibres are read out with silicon photomultipliers (SiPM). Hence, if fibres…
Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…
Proton scattering in some water and tissue equivalent phantom materials was measured to evaluate their simulation accuracy of water and respective human biological tissues. The measurements were performed on the medical facility of the ITEP…
FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in conventional RT. For clinical trials to be conducted safely,…
Tomographic imaging techniques using the Coulomb scattering of cosmic-ray muons are increasingly being exploited for the non-destructive assay of shielded containers in a wide range of applications. One such application is the…
Range uncertainties in proton therapy hamper treatment precision. Prompt gamma-rays were suggested 16 years ago for real-time range verification, and have already shown promising results in clinical studies with collimated cameras.…
Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…
Plastic scintillator detectors are used in high energy physics as well as for diagnostic imaging in medicine, beam monitoring on hadron therapy, muon tomography, dosimetry and many security applications. To combine particle tracking and…
We report on the design, construction, and beam test of a pilot three-dimensional projection detector based on opaque water-based liquid scintillator (oWbLS). The detector consists of an $8 \times 8 \times 16$ cm$^3$ acrylic vessel…
We propose a new scintillator-based tracker concept based on a monolithic plastic scintillator plate with embedded scatterers and wavelength-shifting fiber readout. The embedded scatterers localize scintillation light so that channels…
Recent advances in photon detectors have resulted in high-density imaging arrays that offer many performance and cost advantages. In particular, the excellent transit time spread of certain devices show promise to provide tangible benefits…
Proton radiography is a new scatheless diagnostic tool, and which provides a potential development direction for advanced hydrotesting. Recently a low energy proton radiography system has been developed at CAEP. This system has been…
Two detection systems based on optical readout were developed: a. Integrative optical detector A 2nd generation of Time-Resolved Integrative Optical Neutron (TRION) detector was developed. It is based on an integrative optical technique,…
Background and Objective: Recent experimental studies using ultra-high dose rate radiation therapy (FLASH-RT) have shown improved normal tissue sparing and comparable tumor control compared to conventional dose rate RT. Pencil beam scanning…
We have developed a novel tracking detector utilizing a water-based liquid scintillator (WbLS) for the accurate characterization of neutrino interactions on a water target. In this detector, the WbLS is optically segmented into small cells…
This work explores the combination of liquid xenon as a scintillating medium and silicon photomultipliers as a readout in Positron Emission Tomography (PET) for enhanced Time-Of-Flight resolution. We present the results of our first…
We present a prototype for the first tracking detector consisting of 250 micron thin scintillating fibers and silicon photomultiplier (SiPM) arrays. The detector has a modular design, each module consists of a mechanical support structure…
Background: Organic scintillators are widely used for neutron detection in both basic nuclear physics and applications. While the proton light yield of organic scintillators has been extensively studied, measurements of the light yield from…