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Enabling clinicians and researchers to directly interact with global genomic data resources by removing technological barriers is vital for medical genomics. AskBeacon enables Large Language Models to be applied to securely shared cohorts…

Many research groups aspire to make data and code FAIR and reproducible, yet struggle because the data and code life cycles are disconnected, executable environments are often missing from published work, and technical skill requirements…

Extracting meaningful insights from large and complex datasets poses significant challenges, particularly in ensuring the accuracy and relevance of retrieved information. Traditional data retrieval methods such as sequential search and…

Information Retrieval · Computer Science 2024-09-27 Zahra Sepasdar , Sushant Gautam , Cise Midoglu , Michael A. Riegler , Pål Halvorsen

Over the years, genetic programming (GP) has evolved, with many proposed variations, especially in how they represent a solution. Being essentially a program synthesis algorithm, it is capable of tackling multiple problem domains. Current…

Neural and Evolutionary Computing · Computer Science 2025-04-15 Roman Kalkreuth , Fabricio Olivetti de França , Julian Dierkes , Marie Anastacio , Anja Jankovic , Zdenek Vasicek , Holger Hoos

We present a new approach for the analysis of genome-wide expression data. Our method is designed to overcome the limitations of traditional techniques, when applied to large-scale data. Rather than alloting each gene to a single cluster,…

Biological Physics · Physics 2009-11-07 Sven Bergmann , Jan Ihmels , Naama Barkai

Recent advances in Text-to-SQL have largely focused on the SQLite dialect, neglecting the diverse landscape of SQL dialects like BigQuery and PostgreSQL. This limitation is due to the diversity in SQL syntaxes and functions, along with the…

Artificial Intelligence · Computer Science 2024-10-04 Mohammadreza Pourreza , Ruoxi Sun , Hailong Li , Lesly Miculicich , Tomas Pfister , Sercan O. Arik

We present the data model, design choices, and performance of ProvSQL, a general and easy-to-deploy provenance tracking and probabilistic database system implemented as a PostgreSQL extension. ProvSQL's data and query models closely reflect…

Databases · Computer Science 2025-12-18 Aryak Sen , Silviu Maniu , Pierre Senellart

Large-scale distributed graph-parallel computing is challenging. On one hand, due to the irregular computation pattern and lack of locality, it is hard to express parallelism efficiently. On the other hand, due to the scale-free nature,…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-10-22 Jie Yan , Guangming Tan , Ninghui Sun

We introduce Raqlet, a source-to-source compilation framework that addresses the fragmentation of recursive querying engines spanning relational (recursive SQL), graph (Cypher, GQL), and deductive (Datalog) systems. Recent standards such as…

Databases · Computer Science 2025-08-07 Amir Shaikhha , Youning Xia , Meisam Tarabkhah , Jazal Saleem , Anna Herlihy

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by integrating external knowledge, leading to improved accuracy and relevance. However, scaling RAG pipelines remains computationally expensive as retrieval sizes…

Information Retrieval · Computer Science 2026-03-05 Maxime Louis , Thibault Formal , Hervé Dejean , Stéphane Clinchant

This article highlights some of the key operating principles of Grover algorithm. These principles were used to develop a new oracle function, that illustrates the possibility of using Grover algorithm for solving more realistic and…

Quantum Physics · Physics 2021-09-14 Cesar Borisovich Pronin , Andrey Vladimirovich Ostroukh

While the publication of datasets in scientific repositories has become broadly recognised, the repositories tend to have increasing semantic-related problems. For instance, they present various data reuse obstacles for machine-actionable…

Databases · Computer Science 2021-11-19 Matheus Feijoó , Rodrigo Jardim , Sergio Serra , Maria Luiza Campos

To process data more efficiently, big data frameworks provide data abstractions to developers. However, due to the abstraction, there may be many challenges for developers to understand and debug the data processing code. To uncover the…

Software Engineering · Computer Science 2021-03-29 Zehao Wang

Natural language processing is used for solving a wide variety of problems. Some scholars and interest groups working with language resources are not well versed in programming, so there is a need for a good graphical framework that allows…

Computation and Language · Computer Science 2022-06-17 Timotej Knez , Marko Bajec , Slavko Žitnik

Computational analyses of, e.g., genomic, proteomic, or metabolomic data, commonly result in one or more sets of candidate genes, proteins, or enzymes. These sets are often the outcome of clustering algorithms. Subsequently, it has to be…

Genomics · Quantitative Biology 2007-06-26 Robbe Wunschiers , Martin Vellguth

Conversational search (CS) requires a complex software engineering pipeline that integrates query reformulation, ranking, and response generation. CS researchers currently face two barriers: the lack of a unified framework for efficiently…

Information Retrieval · Computer Science 2026-02-17 Shaojie Jiang , Svitlana Vakulenko , Maarten de Rijke

Temporally indexed data are essential in a wide range of fields and of interest to machine learning researchers. Time series data, however, are often scarce or highly sensitive, which precludes the sharing of data between researchers and…

Machine Learning · Computer Science 2024-07-10 Alexander Nikitin , Letizia Iannucci , Samuel Kaski

Graph structures offer a versatile framework for representing diverse patterns in nature and complex systems, applicable across domains like molecular chemistry, social networks, and transportation systems. While diffusion models have…

Machine Learning · Computer Science 2024-06-10 Adrien Carrel

A private data federation is a set of autonomous databases that share a unified query interface offering in-situ evaluation of SQL queries over the union of the sensitive data of its members. Owing to privacy concerns, these systems do not…

Databases · Computer Science 2018-10-04 Johes Bater , Xi He , William Ehrich , Ashwin Machanavajjhala , Jennie Rogers

Even for a conservative estimate, 80% of enterprise data reside in unstructured files, stored in data lakes that accommodate heterogeneous formats. Classical search engines can no longer meet information seeking needs, especially when the…

Computation and Language · Computer Science 2024-06-06 Qiang Sun , Yuanyi Luo , Wenxiao Zhang , Sirui Li , Jichunyang Li , Kai Niu , Xiangrui Kong , Wei Liu