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The rapid spread of the new SARS-CoV-2 virus triggered a global health crisis disproportionately impacting people with pre-existing health conditions and particular demographic and socioeconomic characteristics. One of the main concerns of…

In epidemic or pandemic situations, resources for testing the infection status of individuals may be scarce. Although group testing can help to significantly increase testing capabilities, the (repeated) testing of entire populations can…

Populations and Evolution · Quantitative Biology 2021-10-29 Günther Koliander , Georg Pichler

Since the onset of the COVID-19 pandemic in 2020, millions of people have succumbed to this deadly virus. Many attempts have been made to devise an automated method of testing that could detect the virus. Various researchers around the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Samyak Prajapati , Japman Singh Monga , Shaanya Singh , Amrit Raj , Yuvraj Singh Champawat , Chandra Prakash

Group testing is an efficient method for testing a large population to detect infected individuals. In this paper, we consider an efficient adaptive two stage group testing scheme. Using a straightforward analysis, we characterize the…

Methodology · Statistics 2020-08-26 Arjun Kodialam

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in connected communities: each individual participates in one or more communities, and…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Sundara Rajan Srinivasavaradhan , Tao Guo , Christina Fragouli , Suhas Diggavi

We propose a monitoring strategy for efficient and robust estimation of disease prevalence and case numbers within closed and enumerated populations such as schools, workplaces, or retirement communities. The proposed design relies largely…

Methodology · Statistics 2024-04-22 Robert H. Lyles , Yuzi Zhang , Lin Ge , Lance A. Waller

The COVID-19 outbreak is asynchronous in US counties. Mitigating the COVID-19 transmission requires not only the state and federal level order of protective measures such as social distancing and testing, but also public awareness of…

Applications · Statistics 2021-05-03 Hanmo Li , Mengyang Gu

The effect of masking the general population on a COVID-19 epidemic is estimated by computer simulation using two separate state-of-the-art web-based softwares, one of them calibrated for the SARS-CoV-2 virus. The questions addressed are…

Populations and Evolution · Quantitative Biology 2020-06-30 Bjorn Johansson

Monitoring the incidence of new infections during a pandemic is critical for an effective public health response. General population prevalence surveys for SARS-CoV-2 can provide high-quality data to estimate incidence. However, estimation…

According to the current perception, symptomatic, presymptomatic, and asymptomatic infectious persons can infect the healthy population susceptible to the SARS-Cov-2. More importantly, various reports indicate that the number of…

Populations and Evolution · Quantitative Biology 2020-11-24 Saptarshi Chatterjee , Apurba Sarkar , Mintu Karmakar , Swarnajit Chatterjee , Raja Paul

Large-scale testing is crucial in pandemic containment, but resources are often prohibitively constrained. We study the optimal application of pooled testing for populations that are heterogeneous with respect to an individual's infection…

Computer Science and Game Theory · Computer Science 2023-09-22 Simon Finster , Michelle González Amador , Edwin Lock , Francisco Marmolejo-Cossío , Evi Micha , Ariel D. Procaccia

Future SARS-CoV-2 virus outbreak COVID-XX might possibly occur during the next years. However the pathology in humans is so recent that many clinical aspects, like early detection of complications, side effects after recovery or early…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 D. Gil , K. Díaz-Chito , C. Sánchez , A. Hernández-Sabaté

Pooled testing is a common strategy for public health disease screening under limited testing resources, allowing multiple biological samples to be tested together with the resources of a single test, at the cost of reduced individual…

Computer Science and Game Theory · Computer Science 2026-02-02 Nicholas Lopez , Francisco Marmolejo-Cossío , Jose Roberto Tello Ayala , David C. Parkes

How may exposure risks to SARS-CoV-2 be assessed quantitatively? The material metabolism approach of Industrial Ecology can be applied to the mass flows of these virions by their numbers, as a key step in the analysis of the current…

Quantitative Methods · Quantitative Biology 2020-10-30 Gjalt Huppes , Ruben Huele

We present two epidemiological models, which extend the classical SEIR model by accounting for the effect of indiscriminate quarantining, isolation of infected individuals based on testing and the presence of asymptomatic individuals. Given…

Dynamical Systems · Mathematics 2020-11-30 Zuzana Chladná , Jana Kopfová , Dmitrii Rachinskii , Pavel Štepánek

Group testing is a method of identifying infected patients by performing tests on a pool of specimens collected from patients. For the case in which the test returns a false result with finite probability, we propose Bayesian inference and…

Machine Learning · Statistics 2020-07-15 Ayaka Sakata

The original problem of group testing consists in the identification of defective items in a collection, by applying tests on groups of items that detect the presence of at least one defective item in the group. The aim is then to identify…

Applications · Statistics 2021-06-10 Emilien Joly , Bastien Mallein

Governments and public health authorities use seroprevalence studies to guide responses to the COVID-19 pandemic. Seroprevalence surveys estimate the proportion of individuals who have detectable SARS-CoV-2 antibodies. However, serologic…

Applications · Statistics 2022-11-11 Samuel P. Rosin , Bonnie E. Shook-Sa , Stephen R. Cole , Michael G. Hudgens

The sequential multiple testing problem is considered under two generalized error metrics. Under the first one, the probability of at least $k$ mistakes, of any kind, is controlled. Under the second, the probabilities of at least $k_1$…

Statistics Theory · Mathematics 2019-02-18 Yanglei Song , Georgios Fellouris

Count data and recurrent events in clinical trials, such as the number of lesions in magnetic resonance imaging in multiple sclerosis, the number of relapses in multiple sclerosis, the number of hospitalizations in heart failure, and the…

Applications · Statistics 2019-03-07 Tobias Mütze , Ekkehard Glimm , Heinz Schmidli , Tim Friede
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