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We analyze the effect of using a screening CT-scan for evaluation of potential COVID-19 infections in order to isolate and perform contact tracing based upon a viral pneumonia diagnosis. RT-PCR is then used for continued isolation based…

Populations and Evolution · Quantitative Biology 2020-06-04 Chen Shen , Ron Mark , Nolan J. Kagetsu , Anton S. Becker , Yaneer Bar-Yam

The detection and management of diseases become quite complicated when pathogens contain asymptomatic phenotypes amongst their ranks, as evident during the recent COVID-19 pandemic. Spreading of diseases has been studied extensively under…

Physics and Society · Physics 2021-10-27 Saptarshi Sinha , Deep Nath , Soumen Roy

In this work we consider the large-coalition asymptotics of various fingerprinting and group testing games, and derive explicit expressions for the capacities for each of these models. We do this both for simple decoders (fast but…

Information Theory · Computer Science 2015-10-01 Thijs Laarhoven

The group testing problem is concerned with identifying a small set of infected individuals in a large population. At our disposal is a testing procedure that allows us to test several individuals together. In an idealized setting, a test…

Information Theory · Computer Science 2023-09-19 Oliver Gebhard , Oliver Johnson , Philipp Loick , Maurice Rolvien

During the early months of the current COVID-19 pandemic, social-distancing measures effectively slowed disease transmission in many countries in Europe and Asia, but the same benefits have not been observed in some developing countries…

In this work, we consider the sparsity-constrained community-based group testing problem, where the population follows a community structure. In particular, the community consists of $F$ families, each with $M$ members. A number $k_f$ out…

Information Theory · Computer Science 2024-03-20 Sarthak Jain , Martina Cardone , Soheil Mohajer

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

Populations and Evolution · Quantitative Biology 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

An accurate multiclass classification strategy is crucial to interpreting antibody tests. However, traditional methods based on confidence intervals or receiver operating characteristics lack clear extensions to settings with more than two…

Quantitative Methods · Quantitative Biology 2024-05-07 Rayanne A. Luke , Anthony J. Kearsley , Paul N. Patrone

The usual development cycles are too slow for the development of vaccines, diagnostics and treatments in pandemics such as the ongoing SARS-CoV-2 pandemic. Given the pressure in such a situation, there is a risk that findings of early…

Applications · Statistics 2020-10-12 Sarah Friedrich , Tim Friede

Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause of the pandemic COVID-19. Early symptoms overlap with other common conditions such as common cold and Influenza, making early screening and diagnosis are…

As a reaction to the pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a multitude of clinical trials for the treatment of SARS-CoV-2 or the resulting corona disease (COVID-19) are globally at various stages from…

Applications · Statistics 2020-12-04 Jan Beyersmann , Tim Friede , Claudia Schmoor

Testing is an important part of tackling the COVID-19 pandemic. Availability of testing is a bottleneck due to constrained resources and effective prioritization of individuals is necessary. Here, we discuss the impact of different…

Machine Learning · Computer Science 2020-07-30 Hagit Grushka-Cohen , Raphael Cohen , Bracha Shapira , Jacob Moran-Gilad , Lior Rokach

Feature or variable selection is a problem inherent to large data sets. While many methods have been proposed to deal with this problem, some can scale poorly with the number of predictors in a data set. Screening methods scale linearly…

Methodology · Statistics 2023-01-09 Naveed Merchant , Jeffrey D. Hart

We present several related methods for creating confidence intervals to assess disease prevalence in variety of survey sampling settings. These include simple random samples with imperfect tests, weighted sampling with perfect tests, and…

Methodology · Statistics 2023-03-14 Damon Bayer , Michael Fay , Barry Graubard

Coronavirus case-count data has influenced government policies and drives most epidemiological forecasts. Limited testing is cited as the key driver behind minimal information on the COVID-19 pandemic. While expanded testing is laudable,…

Methodology · Statistics 2022-09-22 Walter Dempsey

In this paper, we provide insights on how much testing and social distancing is required to control COVID-19. To this end, we develop a compartmental model that accounts for key aspects of the disease: 1) incubation time, 2) age-dependent…

Optimization and Control · Mathematics 2020-11-04 Sara Grundel , Stefan Heyder , Thomas Hotz , Tobias K. S. Ritschel , Philipp Sauerteig , Karl Worthmann

We consider a version of the classical group testing problem motivated by PCR testing for COVID-19. In the so-called tropical group testing model, the outcome of a test is the lowest cycle threshold (Ct) level of the individuals pooled…

Information Theory · Computer Science 2024-10-15 Vivekanand Paligadu , Oliver Johnson , Matthew Aldridge

SARS-CoV-2, also known as COVID-19 or Coronavirus, is a viral contagious disease that is infected by a novel coronavirus, and has been rapidly spreading across the globe. It is very important to test and isolate people to reduce spread, and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Prerak Mann , Sahaj Jain , Saurabh Mittal , Aruna Bhat

COVID-19 continues to cause a significant impact on public health. To minimize this impact, policy makers undertake containment measures that however, when carried out disproportionately to the actual threat, as a result if errorneous…

In this worldwide spread of SARS-CoV-2 (COVID-19) infection, it is of utmost importance to detect the disease at an early stage especially in the hot spots of this epidemic. There are more than 110 Million infected cases on the globe,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 Sohail Iqbal , H. Fareed Ahmed , Talha Qaiser , Muhammad Imran Qureshi , Nasir Rajpoot
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