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With the rise of artificial intelligence in recent years, Deep Neural Networks (DNNs) have been widely used in many domains. To achieve high performance and energy efficiency, hardware acceleration (especially inference) of DNNs is…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-17 Linghao Song , Jiachen Mao , Youwei Zhuo , Xuehai Qian , Hai Li , Yiran Chen

The widespread integration of embedded systems across various industries has facilitated seamless connectivity among devices and bolstered computational capabilities. Despite their extensive applications, embedded systems encounter…

Cryptography and Security · Computer Science 2024-04-16 Sreenitha Kasarapu , Sathwika Bavikadi , Sai Manoj Pudukotai Dinakarrao

The deployment of large language models (LLMs) presents significant challenges due to their enormous memory footprints, low arithmetic intensity, and stringent latency requirements, particularly during the autoregressive decoding stage.…

Hardware Architecture · Computer Science 2025-11-03 Cenlin Duan , Jianlei Yang , Rubing Yang , Yikun Wang , Yiou Wang , Lingkun Long , Yingjie Qi , Xiaolin He , Ao Zhou , Xueyan Wang , Weisheng Zhao

In recent years, the CNNs have achieved great successes in the image processing tasks, e.g., image recognition and object detection. Unfortunately, traditional CNN's classification is found to be easily misled by increasingly complex image…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-12 Xingyao Zhang , Shuaiwen Leon Song , Chenhao Xie , Jing Wang , Weigong Zhang , Xin Fu

One viable solution for continuous reduction in energy-per-operation is to rethink functionality to cope with uncertainty by adopting computational approaches that are inherently robust to uncertainty. It requires a novel look at data…

Emerging Technologies · Computer Science 2018-11-26 Abbas Rahimi , Tony F. Wu , Haitong Li , Jan M. Rabaey , H. -S. Philip Wong , Max M. Shulaker , Subhasish Mitra

In generating large quantities of DNA data, high-throughput sequencing technologies require advanced bioinformatics infrastructures for efficient data analysis. k-mer counting, the process of quantifying the frequency of fixed-length k DNA…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-11 Yifan Li , Giulia Guidi

The emerging field of DNA storage employs strands of DNA bases (A/T/C/G) as a storage medium for digital information to enable massive density and durability. The DNA storage pipeline includes: (1) encoding the raw data into sequences of…

Genomics · Quantitative Biology 2025-01-28 Hadas Abraham , Barak Gahtan , Adir Kobovich , Orian Leitersdorf , Alex M. Bronstein , Eitan Yaakobi

High-throughput sequencing (HTS) technologies have revolutionized the field of genomics, enabling rapid and cost-effective genome analysis for various applications. However, the increasing volume of genomic data generated by HTS…

Hardware Architecture · Computer Science 2023-06-01 Onur Mutlu , Can Firtina

The emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its analysis. In this…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-12 Nicola Cadenelli , Jorda Polo , David Carrera

Nanopore sequencing is an emerging new technology for sequencing DNA, which can read long fragments of DNA (~50,000 bases) in contrast to most current short-read sequencing technologies which can only read hundreds of bases. While nanopore…

Information Theory · Computer Science 2018-02-20 Wei Mao , Suhas Diggavi , Sreeram Kannan

Non-volatile memory (NVM) crossbars have been identified as a promising technology, for accelerating important machine learning operations, with matrix-vector multiplication being a key example. Binary neural networks (BNNs) are especially…

Emerging Technologies · Computer Science 2023-08-14 Ruirong Huang , Zichao Yue , Caroline Huang , Janarbek Matai , Zhiru Zhang

Applications with low data reuse and frequent irregular memory accesses, such as graph or sparse linear algebra workloads, fail to scale well due to memory bottlenecks and poor core utilization. While prior work with prefetching,…

Hardware Architecture · Computer Science 2023-05-05 Marcelo Orenes-Vera , Esin Tureci , David Wentzlaff , Margaret Martonosi

This work presents HAWX, a hardware-aware scalable exploration framework that employs multi-level sensitivity scoring at different DNN abstraction levels (operator, filter, layer, and model) to guide selective integration of heterogeneous…

Machine Learning · Computer Science 2026-02-24 Samira Nazari , Mohammad Saeed Almasi , Mahdi Taheri , Ali Azarpeyvand , Ali Mokhtari , Ali Mahani , Christian Herglotz

Today's computing systems require moving data back-and-forth between computing resources (e.g., CPUs, GPUs, accelerators) and off-chip main memory so that computation can take place on the data. Unfortunately, this data movement is a major…

Hardware Architecture · Computer Science 2022-05-31 Geraldo F. Oliveira , Amirali Boroumand , Saugata Ghose , Juan Gómez-Luna , Onur Mutlu

This paper aims at integrating three powerful techniques namely Deep Learning, Approximate Computing, and Low Power Design into a strategy to optimize logic at the synthesis level. We utilize advances in deep learning to guide an…

Hardware Architecture · Computer Science 2020-07-06 Ghasem Pasandi , Mackenzie Peterson , Moises Herrera , Shahin Nazarian , Massoud Pedram

High-throughput solid-state nanopore experiments generate continuous MHz-rate data streams in which only a small fraction of data contains informative molecular information. This creates storage and processing bottlenecks that limit…

Recently, analog compute-in-memory (CIM) architectures based on emerging analog non-volatile memory (NVM) technologies have been explored for deep neural networks (DNN) to improve energy efficiency. Such architectures, however, leverage…

Signal Processing · Electrical Eng. & Systems 2020-08-07 Zhe Wan , Tianyi Wang , Yiming Zhou , Subramanian S. Iyer , Vwani P. Roychowdhury

Probabilistic reasoning is an essential tool for robust decision-making systems because of its ability to explicitly handle real-world uncertainty, constraints and causal relations. Consequently, researchers are developing hybrid models by…

Hardware Architecture · Computer Science 2021-03-02 Nimish Shah , Laura I. Galindez Olascoaga , Wannes Meert , Marian Verhelst

High-performance Host processors can integrate Processing-In-Memory (PIM) devices, which can accelerate memory-intensive kernels of Machine Learning (ML) models, including Large Language Models (LLMs), by leveraging the large memory…

In-DRAM Processing-In-Memory (DRAM-PIM) has emerged as a promising approach to accelerate memory-intensive workloads by mitigating data transfer overhead between DRAM and the host processor. Bit-serial DRAM-PIM architectures, further…

Hardware Architecture · Computer Science 2025-12-11 Siyuan Ma , Jiajun Hu , Jeeho Ryoo , Aman Arora , Lizy Kurian John