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Related papers: Characterizing SARS-CoV-2 mutations in the United …

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The identification of the transmission parameters of a virus is fundamental to identify the optimal public health strategy. These parameters can present significant changes over time caused by genetic mutations or viral recombination,…

Populations and Evolution · Quantitative Biology 2022-07-21 Eugenio Lippiello , Giuseppe Petrillo , Lucilla de Arcangelis

A genome, composed of a precisely ordered sequence of four nucleotides (ATCG), encompasses a multitude of specific genome features like AAA motif. Mutations occurring within a genome disrupt the sequential order and composition of these…

Other Quantitative Biology · Quantitative Biology 2024-03-26 Anyou Wang

The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global medical systems and economies, and rules our daily living life. Controlling the outbreak of SARS-CoV-2 has become one of the most important…

Medical Physics · Physics 2020-10-09 Jing Zhong , Enja Laureen Roesch , Thilo Viereck , Meinhard Schilling , Frank Ludwig

A comprehensive retrospective analysis of public health interventions, such as large scale testing, quarantining, and contact tracing, can help identify mechanisms most effective in mitigating COVID-19. We investigate China based SARS-CoV-2…

Machine Learning · Computer Science 2025-12-30 Zhou Yang , Edward Dougherty , Chen Zhang , Zhenhe Pan , Fang Jin

The outbreak of COVID-19 caused by SARS-CoV-2 has rapidly spread worldwide and has caused over 1,400,000 infections and 80,000 deaths. There are currently no drugs or vaccines with proven efficacy for its prevention and little knowledge was…

Genomics · Quantitative Biology 2020-04-13 Zhi Liu , Jianwei Wang , Yuyu Xu , Mengchen Guo , Kai Mi , Rui Xu , Yang Pei , Qiangkun Zhang , Xiaoting Luan , Zhibin Hu , Xingyin Liu#

In this study, we propose a time-dependent Susceptible-Exposed-Infected-Recovered (SEIR) model for the analysis of the SARS-CoV-2 epidemic outbreak in three different countries, the United States of America, Italy and Iceland using public…

Populations and Evolution · Quantitative Biology 2021-11-08 P. Girardi , C. Gaetan

Despite the availability of effective vaccines, the persistence of SARS-CoV-2 suggests that co-circulation with other pathogens and resulting multi-epidemics may become increasingly frequent. To better forecast and control the risk of such…

We consider the dynamics of a virus spreading through a population that produces a mutant strain with the ability to infect individuals that were infected with the established strain. Temporary cross-immunity is included using a time delay,…

Populations and Evolution · Quantitative Biology 2023-02-16 Bruce Pell , Samantha Brozak , Tin Phan , Fuqing Wu , Yang Kuang

The rapid spread of the new SARS-CoV-2 virus triggered a global health crisis disproportionately impacting people with pre-existing health conditions and particular demographic and socioeconomic characteristics. One of the main concerns of…

There is a near consensus view that SARS-CoV-2 has a natural zoonotic origin; however, several characteristics of SARS-CoV-2 taken together are not easily explained by a natural zoonotic origin hypothesis. These include: a low rate of…

Populations and Evolution · Quantitative Biology 2021-02-10 Rossana Segreto , Yuri Deigin , Kevin McCairn , Alejandro Sousa , Dan Sirotkin , Karl Sirotkin , Jonathan J. Couey , Adrian Jones , Daoyu Zhang

The COVID-19 (coronavirus) is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was first identified in mid-December 2019 in the Hubei province of Wuhan, China and by now has spread…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Aditya Saxena , Shamsheer Pal Singh

The Coronavirus Disease 2019 or the COVID-19 pandemic has swept almost all parts of the world since the first case was found in Wuhan, China, in December 2019. With the increasing number of COVID-19 cases in the world, SARS-CoV-2 has…

Computational Engineering, Finance, and Science · Computer Science 2023-01-31 Akhmad Dimitri Baihaqi , Novanto Yudistira , Edy Santoso

The SARS-CoV-2 outbreak changed the everyday life of almost all the people over the world.Currently, we are facing with the problem of containing the spread of the virus both using the more effective forced lockdown, which has the drawback…

Social and Information Networks · Computer Science 2021-03-23 Alessandro Nuara , Francesco Trovò , Nicola Gatti

This paper presents a federated learning (FL) approach to train an AI model for SARS-Cov-2 variant classification. We analyze the SARS-CoV-2 spike sequences in a distributed way, without data sharing, to detect different variants of this…

Machine Learning · Computer Science 2023-11-10 Prakash Chourasia , Taslim Murad , Zahra Tayebi , Sarwan Ali , Imdad Ullah Khan , Murray Patterson

Background: Global viral threats underscore the need for effective genomic surveillance, but high costs and uneven resource distribution hamper its implementation. Targeting surveillance to international travelers in major travel hubs may…

Populations and Evolution · Quantitative Biology 2025-02-14 Haogao Gu , Jifan Li , Wanying Sun , Mengting Li , Kathy Leung , Joseph T. Wu , Hsiang-Yu Yuan , Maggie H. Wang , Bingyi Yang , Matthew R. McKay , Ning Ning , Leo L. M. Poon

The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly replaced the Delta variant as a dominating SARS-CoV-2 variant because of natural selection, which favors the variant with higher infectivity and…

Populations and Evolution · Quantitative Biology 2022-02-11 Jiahui Chen , Guo-Wei Wei

A new coronavirus disease, called COVID-19, appeared in the Chinese region of Wuhan at the end of last year; since then the virus spread to other countries, including most of Europe. We propose a differential equation governing the…

Populations and Evolution · Quantitative Biology 2020-09-15 Giorgio Sonnino , Pasquale Nardone

Facing a global challenge with over 6.9 million fatalities, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoViD-19, demands novel and comprehensive approaches to understand its complex dynamics. This…

Dynamical Systems · Mathematics 2023-06-05 João Paulo Simões Maurício de Carvalho

SARS-CoV is believed to originate from civets and was thought to have been eliminated as a threat after the 2003 outbreak. Here, we show that human SARS-CoV (huSARS-CoV) originated directly from bats, rather than civets, by a cross-species…

Populations and Evolution · Quantitative Biology 2013-05-15 Ailin Tao , Yuyi Huang , Peilu Li , Jun Liu , Nanshan Zhong , Chiyu Zhang

The novel coronavirus SARS-CoV-2 and resulting COVID-19 disease have had an unprecedented spread and continue to cause an increasing number of fatalities worldwide. While vaccines are still under development, social distancing, extensive…

Populations and Evolution · Quantitative Biology 2020-07-02 Calvin Tsay , Fernando Lejarza , Mark A. Stadtherr , Michael Baldea