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Related papers: Characterizing SARS-CoV-2 mutations in the United …

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The increasing spread of COVID-19, caused by the virus SARS-CoV-2, raises concerns about the extent to which mutations have occurred across the viral genome. We present a partial replication of an earlier 2021 study by Wang, R. et al. that…

Genomics · Quantitative Biology 2021-12-28 William Svoboda , Brendan McManamon , Sara Schwartz

The emerging global infectious COVID-19 coronavirus disease by novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and the economy since it was identified in late December…

Genomics · Quantitative Biology 2020-03-25 Changchuan Yin

The transmission and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of paramount importance to the controlling and combating of coronavirus disease 2019 (COVID-19) pandemic. Currently, near 15,000 SARS-CoV-2…

Genomics · Quantitative Biology 2020-08-21 Rui Wang , Yuta Hozumi , Yong-Hui Zheng , Changchuan Yin , Guo-Wei Wei

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity is a major concern in coronavirus disease 2019 (COVID-19) prevention and economic reopening. However, rigorous determination of SARS-COV-2 infectivity is essentially…

Biomolecules · Quantitative Biology 2020-06-01 Jiahui Chen , Rui Wang , Menglun Wang , Guo-Wei Wei

Tremendous effort has been given to the development of diagnostic tests, preventive vaccines, and therapeutic medicines for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much of…

Genomics · Quantitative Biology 2020-04-30 Rui Wang , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

Accurate and reliable forecasting of emerging dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants enables policymakers and vaccine makers to get prepared for future waves of infections. The last three waves of…

Populations and Evolution · Quantitative Biology 2022-10-19 Jiahui Chen , Rui Wang , Yuta Hozumi , Gengzhuo Liu , Yuchi Qiu , Xiaoqi Wei , Guo-Wei Wei

The importance of understanding SARS-CoV-2 evolution cannot be overemphasized. Recent studies confirm that natural selection is the dominating mechanism of SARS-CoV-2 evolution, which favors mutations that strengthen viral infectivity. We…

Populations and Evolution · Quantitative Biology 2021-10-12 Rui Wang , Jiahui Chen , Guo-Wei Wei

The SARS-CoV-2 pandemic has so far unfolded diversely across the fifty United States of America, reflected both in different time progressions of infection "waves" and in magnitudes of local infection rates. Despite a marked diversity of…

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus of beta coronavirus genus originated in Wuhan, China in December 2019, resulted in the pandemic spread of Corona Virus Disease 2019 (COVID-19) worldwide. This genus…

Tissues and Organs · Quantitative Biology 2020-06-17 Mohammed A. El-Magd

Effective, sensitive, and reliable diagnostic reagents are of paramount importance for combating the ongoing coronavirus disease 2019 (COVID-19) pandemic at a time there is no preventive vaccine nor specific drug available for severe acute…

Genomics · Quantitative Biology 2020-05-06 Rui Wang , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

As the year 2020 draws to an end, several new strains have been reported for the SARS-CoV-2 coronavirus, the agent responsible for the COVID-19 pandemic that has afflicted us all this past year. However, it is difficult to comprehend the…

Genomics · Quantitative Biology 2023-06-09 Rene L. Warren , Inanc Birol

SARS-CoV-2 is an upper respiratory system RNA virus that has caused over 3 million deaths and infecting over 150 million worldwide as of May 2021. With thousands of strains sequenced to date, SARS-CoV-2 mutations pose significant challenges…

Quantitative Methods · Quantitative Biology 2021-11-15 Yanyi Ding , Zhiyi Kuang , Yuxin Pei , Jeff Tan , Ziyu Zhang , Joseph Konan

The widespread availability of large amounts of genomic data on the SARS-CoV-2 virus, as a result of the COVID-19 pandemic, has created an opportunity for researchers to analyze the disease at a level of detail unlike any virus before it.…

Machine Learning · Computer Science 2021-10-20 Zahra Tayebi , Sarwan Ali , Murray Patterson

SARS-CoV-2, like any other virus, continues to mutate as it spreads, according to an evolutionary process. Unlike any other virus, the number of currently available sequences of SARS-CoV-2 in public databases such as GISAID is already…

Populations and Evolution · Quantitative Biology 2021-10-13 Sarwan Ali , Tamkanat-E-Ali , Muhammad Asad Khan , Imdadullah Khan , Murray Patterson

During 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission has been increasing amongst the world's population at an alarming rate. Reducing the spread of SARS-CoV-2 and other diseases that are spread in…

Social and Information Networks · Computer Science 2022-03-22 Patrick Urrutia , David Wren , Chrysafis Vogiatzis , Ruriko Yoshida

We compute the allele frequencies of the alpha (B.1.1.7), beta (B.1.351) and delta (B.167.2) variants of SARS-CoV-2 from almost two million genome sequences on the GISAID repository. We find that the frequencies of a majority of the…

Populations and Evolution · Quantitative Biology 2021-09-08 Hong-Li Zeng , Yue Liu , Vito Dichio , Kaisa Thorell , Rickard Nordén , Erik Aurell

The COVID-19 pandemic has profoundly affected global health, driven by the remarkable transmissibility and mutational adaptability of the SARS-CoV-2 virus. Although five variants of concern, Alpha, Beta, Gamma, Delta, and Omicron, have been…

Genomics · Quantitative Biology 2026-05-07 Bo Jing , Kai-Rui Zhang , Hong-Li Zeng , Erik Aurell

The recent global surge in COVID-19 infections has been fueled by new SARS-CoV-2 variants, namely Alpha, Beta, Gamma, Delta, etc. The molecular mechanism underlying such surge is elusive due to 4,653 non-degenerate mutations on the spike…

Biomolecules · Quantitative Biology 2021-09-13 Rui Wang , Jiahui Chen , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and propagated worldwide as a pandemic. In the absence of preventive medicine or a ready to use vaccine, mathematical models can provide useful scientific insights…

Populations and Evolution · Quantitative Biology 2020-06-30 Indrajit Ghosh
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