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Background: The COVID-19 pandemic clock is ticking and the survival of many of mankind's modern institutions and or survival of many individuals is at stake. There is a need for treatments to significantly reduce the morbidity and mortality…

Genomics · Quantitative Biology 2020-12-08 Ali Ebrahimpour Boroojeny , Hamidreza Chitsaz

In this work, we developed a deep learning model-based approach to forecast the spreading trend of SARS-CoV-2 in the United States. We implemented the designed model using the United States to confirm cases and state demographic data and…

Computers and Society · Computer Science 2020-08-14 Tong Yang , Long Sha , Justin Li , Pengyu Hong

The reason of significantly higher transmissibility of SARS Covid (2019 CoV-2) compared to SARS Covid (2003 CoV) and MERS Covid (2012 MERS) can be attributed to mutations reported in structural proteins, and the role played by…

Biomolecules · Quantitative Biology 2022-02-25 Raju Hazari , P Pal Chaudhuri

Determining who is at risk from a disease is important in order to protect vulnerable subpopulations during an outbreak. We are currently in a SARS-COV-2 (commonly referred to as COVID-19) pandemic which has had a massive impact across the…

Applications · Statistics 2023-03-28 Sarah Good , Anthony O'Hare

In the United States, from the start of the COVID-19 pandemic to December 31, 2020, 341,199 deaths and more than 19,663,976 infections were recorded. Recent literature establishes that communities with poverty-related health problems, such…

Applications · Statistics 2021-02-09 Cesar R. Salas-Guerra

Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the…

COVID-19 is an emergent viral infection which rose in December 2019 in a city in the Chinese province of Hubei, Wuhan; the viral aetiology of this infection is now known as COVID-19 virus, which belongs to the Betacoronavirus genus. This…

Populations and Evolution · Quantitative Biology 2020-03-17 Alfonso Vivanco-Lira

COVID-19 patients show varying severity of the disease ranging from asymptomatic to requiring intensive care. Although a number of SARS-CoV-2 specific monoclonal antibodies have been identified, we still lack an understanding of the overall…

This paper proposes a cluster-based method to analyze the evolution of multivariate time series and applies this to the COVID-19 pandemic. On each day, we partition countries into clusters according to both their case and death counts. The…

Methodology · Statistics 2020-07-07 Nick James , Max Menzies

We propose two stochastic models for the Coronavirus pandemic. The statistical properties of the models, in particular the correlation functions and the probability density function, have duly been computed. Our models, which generalises a…

Medical Physics · Physics 2020-12-04 Giorgio Sonnino , Fernando Mora , Pasquale Nardone

Interactions between SARS-CoV-2 and the immune system during infection are complex. However, understanding the within-host SARS-CoV-2 dynamics is of enormous importance, especially when it comes to assessing treatment options. Mathematical…

Quantitative Methods · Quantitative Biology 2023-12-11 Lea Schuh , Peter V. Markov , Vladimir M. Veliov , Nikolaos I. Stilianakis

Characterising drivers of SARS-CoV-2 circulation is crucial for understanding COVID-19 because of the severity of control measures adopted during the pandemic. Whole genome sequence data augmented with demographic metadata provides the best…

Populations and Evolution · Quantitative Biology 2024-09-17 Anna Gamża , Samantha Lycett , Will Harvey , Joseph Hughes , Sema Nickbakhsh , David L Robertson , Alison Smith Palmer , Anthony Wood , Rowland Kao

With the rapid spread of COVID-19 worldwide, viral genomic data is available in the order of millions of sequences on public databases such as GISAID. This Big Data creates a unique opportunity for analysis towards the research of effective…

Machine Learning · Computer Science 2022-10-14 Sarwan Ali , Babatunde Bello , Zahra Tayebi , Murray Patterson

The recent epidemic of Coronavirus (COVID-19) that started in China has already been "exported" to more than 140 countries in all the continents, evolving in most of them by local spreading. In this contribution we analyze the trends of the…

Populations and Evolution · Quantitative Biology 2020-03-23 Albertine Weber , Flavio Ianelli , Sebastian Goncalves

The rapid evolution and global impact of coronaviruses, notably SARS-CoV-1 and SARS-CoV-2, underscore the importance of understanding their molecular mechanisms in detail. This study focuses on the receptor-binding motif (RBM) within the…

Biological Physics · Physics 2026-03-16 Rafael B. Frigori

The novel coronavirus SARS-CoV-2, commonly referred to as COVID-19, triggered the global pandemic. Although the nature of the international spread of infection is an important issue, extracting diffusion networks from observations is…

Social and Information Networks · Computer Science 2024-01-12 Hiroyasu Inoue , Wataru Souma , Yoshi Fujiwara

The world is currently experiencing an ongoing pandemic of an infectious disease named coronavirus disease 2019 (i.e., COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Computed Tomography (CT)…

Image and Video Processing · Electrical Eng. & Systems 2021-12-10 Qinghao Ye , Yuan Gao , Weiping Ding , Zhangming Niu , Chengjia Wang , Yinghui Jiang , Minhao Wang , Evandro Fei Fang , Wade Menpes-Smith , Jun Xia , Guang Yang

Understanding the viral dynamics and immunizing antibodies of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for devising better therapeutic and prevention strategies for COVID-19. Here, we present a Bayesian…

Applications · Statistics 2023-07-27 Tracy Q. Dong , Elizabeth R. Brown

During the SARS-CoV-2 pandemic, wastewater-based genomic surveillance (WWGS) emerged as an efficient viral surveillance tool that takes into account asymptomatic cases and can identify known and novel mutations and offers the opportunity to…

Researchers across the globe are seeking to rapidly repurpose existing drugs or discover new drugs to counter the the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One promising…

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