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A phase field model for dealing with shape instabilities in fluid membrane vesicles is presented. This model takes into account the Canham-Helfrich bending energy with spontaneous curvature. A dynamic equation for the phase-field is also…

Soft Condensed Matter · Physics 2007-07-26 F. Campelo , A. Hernandez-Machado

Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…

Tissues and Organs · Quantitative Biology 2023-03-08 Nen Saito , Shuji Ishihara

Membrane-induced interactions have been predicted to be important for the organization of membrane proteins. Measurements of the interactions between two and three membrane deforming objects have revealed their non-additive nature. They are…

Soft Condensed Matter · Physics 2024-03-11 Ali Azadbakht , Thomas R. Weikl , Daniela J. Kraft

We study the equilibrium shapes of vesicles, with an in-plane nematic order, using a Monte-Carlo scheme and show that highly curved shapes, like tubes and discs, with a striking similarity to the structures engendered by certain curvature…

Biological Physics · Physics 2012-02-16 N. Ramakrishnan , John H. Ipsen , P. B. Sunil Kumar

Membrane proteins are crucial in regulating biomembrane shapes and controlling the dynamic changes in membrane morphology during essential cellular processes. These proteins can localize to regions with their preferred curvatures (curvature…

Soft Condensed Matter · Physics 2025-05-26 Hiroshi Noguchi

The deformation of cellular membranes regulates trafficking processes, such as exocytosis and endocytosis. Classically, the Helfrich continuum model is used to characterize the forces and mechanical parameters that cells tune to accomplish…

Quantitative Methods · Quantitative Biology 2022-06-14 Sage Malingen , Padmini Rangamani

Shear-flow-induced structure formation in surfactant-water mixtures is investigated numerically using a meshless-membrane model in combination with a particle-based hydrodynamics simulation approach for the solvent. At low shear rates,…

Soft Condensed Matter · Physics 2013-07-02 Hayato Shiba , Hiroshi Noguchi , Gerhard Gompper

In the framework of a phase field model of a single cell crawling on a substrate, we investigate how the properties of the cell membrane affect the shape and motility of the cell. Since the membrane influences the cell dynamics on multiple…

Soft Condensed Matter · Physics 2016-03-23 Benjamin Winkler , Igor S. Aranson , Falko Ziebert

We study the pattern formation of chiral charges in the presence of reactions. We show that, in contrast to the original Turing's mechanism of pattern formation in diffusion-reaction systems, the interplay between chiral effects and…

Statistical Mechanics · Physics 2018-08-02 Naoki Yamamoto

We report experimental observations of an undulational instability of myelin figures. Motivated by this, we examine theoretically the deformation and possible instability of concentric, cylindrical, multi-lamellar membrane structures. Under…

Soft Condensed Matter · Physics 2009-11-07 C. -M. Chen , C. F. Schmidt , P. D. Olmsted , F. C. MacKintosh

Living systems are chiral on multiple scales, from constituent biopolymers to large scale morphology, and their active mechanics is both driven by chiral components and serves to generate chiral morphologies. We describe the mechanics of…

Soft Condensed Matter · Physics 2023-07-03 Sami C. Al-Izzi , Gareth P. Alexander

Biological, physical, medical, and numerical applications involving membrane problems on different scales are numerous. We propose an extension of the standard Turing theory to the case of two domains separated by a permeable membrane. To…

Analysis of PDEs · Mathematics 2022-03-04 Giorgia Ciavolella

We present a generic framework for modelling three-dimensional deformable shells of active matter that captures the orientational dynamics of the active particles and hydrodynamic interactions on the shell and with the surrounding…

Soft Condensed Matter · Physics 2019-11-20 Luuk Metselaar , Julia M. Yeomans , Amin Doostmohammadi

We perform the linear stability analysis for a new model for poromechanical processes with inertia (formulated in mixed form using the solid deformation, fluid pressure, and total pressure) interacting with diffusing and reacting solutes…

We study the shape dynamics of a two-component fluid membrane, using a dynamical triangulation monte carlo simulation and a Langevin description. Phase separation induces morphology changes depending on the lateral mobility of the lipids.…

Soft Condensed Matter · Physics 2009-10-30 P. B. Sunil Kumar , Madan Rao

Weakly nonlinear amplitude equations are derived for the onset of spatially extended patterns on a general class of n-component bulk-surface reaction-diffusion systems in a ball, under the assumption of linear kinetics in the bulk and…

Pattern Formation and Solitons · Physics 2025-05-27 Edgardo Villar-Sepúlveda , Alan R. Champneys , Davide Cusseddu , Anotida Madzvamuse

A variety of models for the membrane-mediated interaction of particles in lipid membranes, mostly well-established in theoretical physics, is reviewed from a mathematical perspective. We provide mathematically consistent formulations in a…

Analysis of PDEs · Mathematics 2016-06-29 Charles M. Elliott , Carsten Gräser , Graham Hobbs , Ralf Kornhuber , Maren-Wanda Wolf

This study investigates transient wave dynamics in Turing pattern formation, focusing on waves emerging from localised disturbances. While the traditional focus of diffusion-driven instability has primarily centred on stationary solutions,…

Pattern Formation and Solitons · Physics 2024-03-15 Václav Klika , Eamonn A. Gaffney , Philip K. Maini

The domain formation of curvature-inducing molecules, such as peripheral or transmembrane proteins and conical surfactants, is studied in thermal equilibrium and nonequilibrium steady states using meshless membrane simulations. These…

Soft Condensed Matter · Physics 2023-01-30 Hiroshi Noguchi

We analyze the non-equilibrium shape fluctuations of giant unilamellar vesicles encapsulating motile bacteria. Owing to bacteria--membrane collisions, we experimentally observe a significant increase in the magnitude of membrane…

Soft Condensed Matter · Physics 2020-04-22 Sho C. Takatori , Amaresh Sahu
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