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Many cellular organelles are membrane-bound structures with complex membrane composition and shape. Their shapes have been observed to depend on the metabolic state of the organelle, and the mechanisms that couple biochemical pathways and…

Soft Condensed Matter · Physics 2023-07-19 Toni V. Mendes , Jonas Ranft , Hélène Berthoumieux

The assembly of banana-shaped rodlike proteins on membranes, and the associated membrane shape transformations, are investigated by analytical theory and coarse-grained simulations. The membrane-mediated interactions between two…

Soft Condensed Matter · Physics 2017-05-15 Hiroshi Noguchi , Jean-Baptiste Fournier

Patterns in reaction-diffusion systems often contain two spatial scales; a long scale determined by a typical wavelength or domain size, and a short scale pertaining to front structures separating different domains. Such patterns naturally…

patt-sol · Physics 2009-10-22 Aric Hagberg , Ehud Meron

The biological function of membranes is closely related to their softness, which is often studied through the membranes' thermally-driven fluctuations. The analysis commonly assumes that the relaxation rate of a pure bending deformation is…

Soft Condensed Matter · Physics 2024-07-09 Hammad A. Faizi , Rony Granek , Petia M. Vlahovska

We study the effect of membrane proteins on the shape, composition and thermodynamic stability of the surrounding membrane. When the coupling between membrane composition and curvature is strong enough the nearby composition and shape both…

Soft Condensed Matter · Physics 2015-03-11 S. Alex Rautu , George Rowlands , Matthew S. Turner

Understanding how patterns and travelling waves form in chemical and biological reaction-diffusion models is an area which has been widely researched, yet is still experiencing fast development. Surprisingly enough, we still do not have a…

Populations and Evolution · Quantitative Biology 2018-05-24 Andrea Cangiani , Emmanuil H. Georgoulis , Andrew Yu. Morozov , Oliver J. Sutton

Thermal fluctuations strongly modify the large length-scale elastic behavior of crosslinked membranes, giving rise to scale-dependent elastic moduli. While thermal effects in flat membranes are well understood, many natural and artificial…

Soft Condensed Matter · Physics 2013-02-19 Jayson Paulose , Gerard A. Vliegenthart , Gerhard Gompper , David R. Nelson

Simulations show that when a phase-separated binary AB fluid is driven to flow past chemically patterned substrates in a microchannel, the fluid exhibits unique morphological instabilities. For the pattern studied, these instabilities give…

Soft Condensed Matter · Physics 2009-11-10 Olga Kuksenok , David Jasnow , Julia Yeomans , Anna C. Balazs

A transient analysis for vesicle deformation under DC electric fields is developed. The theory extends from a droplet model, with the additional consideration of a lipid membrane separating two fluids of arbitrary properties. For the…

Biological Physics · Physics 2015-06-12 Jia Zhang , Jeffery D. Zahn , Wenchang Tan , Hao Lin

An analytical theory is developed to describe the dynamics of a closed lipid bilayer membrane (vesicle) freely suspended in a general linear flow. Considering a nearly spherical shape, the solution to the creeping-flow equations is obtained…

Biological Physics · Physics 2009-11-13 Petia M. Vlahovska , Ruben Serral Gracia

The present study addresses the reaction zone structure and burning mechanism of unstable detonations. Experiments investigated mainly two-dimensional methane-oxygen cellular detonations in a thin channel geometry. The sufficiently high…

We present a nonequlibrium approach for the study of a flexible bilayer whose two components induce distinct curvatures. In turn, the two components are interconverted by an externally promoted reaction. Phase separation of the two species…

Soft Condensed Matter · Physics 2009-11-11 Ramon Reigada , Javier Buceta , Katja Lindenberg

Cell plasma membranes display a dramatically rich structural complexity characterized by functional sub-wavelength domains with specific lipid and protein composition. Under favorable experimental conditions, patterned morphologies can also…

Soft Condensed Matter · Physics 2018-10-02 Nicolas Destainville , Manoel Manghi , Julie Cornet

The study of pattern emergence together with exploration of the exemplar Turing model is enjoying a renaissance both from theoretical and experimental perspective. Here, we implement a stability analysis of spatially dependent reaction…

Pattern Formation and Solitons · Physics 2019-11-06 Michal Kozák , Eamonn A Gaffney , Václav Klika

The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or…

Soft Condensed Matter · Physics 2009-11-10 Pierre Sens

Autophagy is an intracellular degradation process that is mediated by de novo formation of autophagosomes. Autophagosome formation involves dynamic morphological changes; a disk-shaped membrane cisterna grows, bends to become a cup-shaped…

Biological Physics · Physics 2020-09-04 Yuji Sakai , Ikuko Koyama-Honda , Masashi Tachikawa , Roland L. Knorr , Noboru Mizushima

Turing patterns are stationary, wave-like structures that emerge from the nonequilibrium assembly of reactive and diffusive components. While they are foundational in biophysics, their classical formulation relies on a single characteristic…

Soft Condensed Matter · Physics 2026-01-30 Siamak Mirfendereski , Ankur Gupta

Living cells respond to mechanical changes in the matrix surrounding them by applying contractile forces that are in turn transmitted to distant cells. We calculate the mechanical work that each cell performs in order to deform the matrix,…

Soft Condensed Matter · Physics 2021-08-17 Chaviva Sirote , Yair Shokef

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

Biological Physics · Physics 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

Phase-separated biomolecular condensates with liquid-like properties play a key role in the organization and compartmentalization of the intracellular environment. Condensate-mediated capillary forces acting on membranes drive…