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Reversible logic has applications in various research areas including signal processing, cryptography and quantum computation. In this paper, direct NCT-based synthesis of a given $k$-cycle in a cycle-based synthesis scenario is examined.…

Quantum Physics · Physics 2012-09-04 Mehdi Saeedi , Morteza Saheb Zamani , Mehdi Sedighi , Zahra Sasanian

The "crisis of reproducibility" has been a significant source of controversy, heated debate, and calls for reform to institutional science in recent years. As a long-term solution to address both the present crisis and future obstacles, I…

Computers and Society · Computer Science 2018-04-24 Gopal P. Sarma

To address the global health threat of antimicrobial resistance, antimicrobial peptides (AMP) are being explored for their potent and promising ability to fight resistant pathogens. While artificial intelligence (AI) is being employed to…

Artificial Intelligence · Computer Science 2026-02-17 Gen Zhou , Sugitha Janarthanan , Lianghong Chen , Pingzhao Hu

Antibiotic Resistance (AR) is a critical global health challenge that necessitates the development of cost-effective, efficient, and accurate diagnostic tools. Given the genetic basis of AR, techniques such as Polymerase Chain Reaction…

Quantitative Methods · Quantitative Biology 2025-02-24 David Hagerman , Anna Johnning , Roman Naeem , Fredrik Kahl , Erik Kristiansson , Lennart Svensson

"The Price of Robustness" by Bertsimas and Sim represented a breakthrough in the development of a tractable robust counterpart of Linear Programming Problems. However, the central modeling assumption that the deviation band of each…

Optimization and Control · Mathematics 2014-10-24 Christina Büsing , Fabio D'Andreagiovanni

The CRISPR (clustered regularly interspaced short palindromic repeats) mechanism allows bacteria to adaptively defend against phages by acquiring short genomic sequences (spacers) that target specific sequences in the viral genome. We…

Biological Physics · Physics 2019-09-11 Serena Bradde , Marija Vucelja , Tiberiu Tesileanu , Vijay Balasubramanian

A major public health issue is the growing resistance of bacteria to antibiotics. An important part of the needed response is the discovery and development of new antimicrobial strategies. These require the screening of potential new drugs,…

Applications · Statistics 2026-02-19 Byran Smucker , Benjamin Brennan , Emily Rego , Meng Wu , Zhihong Lin , Brian Ahmer , Blake Peterson

When can interventions in markets be designed to increase surplus robustly -- i.e., with high probability -- accounting for uncertainty due to imprecise information about economic primitives? In a setting with many strategic firms, each…

Theoretical Economics · Economics 2025-01-06 Andrea Galeotti , Benjamin Golub , Sanjeev Goyal , Eduard Talamàs , Omer Tamuz

Reverse pricing has been recognized as an effective tool to handle demand uncertainty in the travel industry (e.g., airlines and hotels). To investigate its viability for communication networks, we study the practical limitations of…

Networking and Internet Architecture · Computer Science 2016-03-23 Sang Yeob Jung , Seong-Lyun Kim

In this paper, we study the problem of recovering two unknown signals from their convolution, which is commonly referred to as blind deconvolution. Reformulation of blind deconvolution as a low-rank recovery problem has led to multiple…

Information Theory · Computer Science 2023-03-20 Julia Kostin , Felix Krahmer , Dominik Stöger

The emergence of the phenomenon known as ABR (anti-bacterial resistance), is the result of the gradual decrease in the efficacy of antibiotics and the increase in the cost of producing new antibiotics. Hence, alternative solutions to…

Populations and Evolution · Quantitative Biology 2024-02-08 Nouf Alghamdi , Mal Horsburgh , Bakhtier Vasiev

The reproduction and replication of research results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the challenges closely revolve around…

Software Engineering · Computer Science 2017-07-31 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

This article proposes a method for measuring the latent risks involved in the recovery process of non performing loans in financial institutions and business firms that deal with collection and recovery processes. To that end, we apply the…

Applications · Statistics 2014-08-20 Mauro R. Oliveira , Francisco Louzada

Biological datasets amenable to applied machine learning are more available today than ever before, yet they lack adequate representation in the Data-for-Good community. Here we present a work in progress case study performing analysis on…

Machine Learning · Statistics 2016-07-06 John W. Santerre , James J. Davis , Fangfang Xia , Rick Stevens

Antimicrobial resistance is an important public health concern that has implications in the practice of medicine worldwide. Accurately predicting resistance phenotypes from genome sequences shows great promise in promoting better use of…

Static Random-Access Memory (SRAM) yield analysis is essential for semiconductor innovation, yet research progress faces a critical challenge: the large gap between simplified academic models and the complexities observed in practice. The…

Hardware Architecture · Computer Science 2025-11-18 Shan Shen , Xingyang Li , Zhuohua Liu , Junhao Ma , Yikai Wang , Yiheng Wu , Yuquan Sun , Wei W. Xing

Traditional drug discovery is a long, expensive, and complex process. Advances in Artificial Intelligence (AI) and Machine Learning (ML) are beginning to change this narrative. Here, we provide a comprehensive overview of different AI and…

Artificial Intelligence · Computer Science 2024-11-12 Khartik Uppalapati , Eeshan Dandamudi , S. Nick Ice , Gaurav Chandra , Kirsten Bischof , Christian L. Lorson , Kamal Singh

This paper provides a novel theory of research joint ventures for financially constrained firms. When firms choose R&D portfolios, an RJV can help to coordinate research efforts, reducing investments in duplicate projects. This can free up…

General Economics · Economics 2024-03-01 Philipp Brunner , Igor Letina , Armin Schmutzler

Antimicrobial resistance (AMR) poses a significant public health and economic challenge, increasing treatment costs and reducing antibiotic effectiveness. This study employs machine learning to analyze genomic and epidemiological data from…

Quantitative Methods · Quantitative Biology 2025-09-05 Shubham Mishra , The Anh Han , Bruno Silvester Lopes , Shatha Ghareeb , Zia Ush Shamszaman

In this work the robustness of a feedback optimization scheme is discussed. Previously known results in literature, on the convergence to local optima of the optimization problem of interest, are extended to the case where the sensitivities…

Optimization and Control · Mathematics 2021-04-01 Mirko Pasquini , Kévin Colin , Véronique Chotteau , Håkan Hjalmarsson